Matches in SemOpenAlex for { <https://semopenalex.org/work/W2111761016> ?p ?o ?g. }
- W2111761016 endingPage "508" @default.
- W2111761016 startingPage "503" @default.
- W2111761016 abstract "Purpose of review Alterations of the renal microcirculation can promote the development of acute kidney injury through the interlinked occurrence of renal hypoxia and activation of inflammatory pathways. This review focuses on the recent advances in this area, and discusses the possible therapeutic interventions that might be derived from these insights. Recent findings Endothelial injury acts as a primary event leading to renal hypoxia with disturbances in nitric oxide pathways playing a major role. The unbalanced homeostasis between nitric oxide, reactive oxygen species and renal oxygenation forms a major component of the microcirculatory dysfunction. Furthermore, injury leads to leukocyte–endothelial interaction that exacerbates renal hypoxia at a microcirculatory level. Summary Knowledge of the pathophysiological mechanisms of acute kidney injury emphasizes the importance of the role of the microcirculation in its development. Preventive and therapeutic approach should be based on restoring the homeostasis between nitric oxide, reactive oxygen species and renal oxygenation." @default.
- W2111761016 created "2016-06-24" @default.
- W2111761016 creator A5040713731 @default.
- W2111761016 creator A5050936569 @default.
- W2111761016 creator A5057342507 @default.
- W2111761016 creator A5091348002 @default.
- W2111761016 date "2009-12-01" @default.
- W2111761016 modified "2023-10-18" @default.
- W2111761016 title "The role of the microcirculation in acute kidney injury" @default.
- W2111761016 cites W1964536962 @default.
- W2111761016 cites W1975729112 @default.
- W2111761016 cites W1977331927 @default.
- W2111761016 cites W1980228387 @default.
- W2111761016 cites W1980969694 @default.
- W2111761016 cites W1982838274 @default.
- W2111761016 cites W1985428538 @default.
- W2111761016 cites W1986861768 @default.
- W2111761016 cites W1991782173 @default.
- W2111761016 cites W1992920273 @default.
- W2111761016 cites W1995615536 @default.
- W2111761016 cites W1999668340 @default.
- W2111761016 cites W2005593895 @default.
- W2111761016 cites W2015380882 @default.
- W2111761016 cites W2016411338 @default.
- W2111761016 cites W2017518622 @default.
- W2111761016 cites W2019690943 @default.
- W2111761016 cites W2021983732 @default.
- W2111761016 cites W2027151815 @default.
- W2111761016 cites W2027657646 @default.
- W2111761016 cites W2030910315 @default.
- W2111761016 cites W2033169788 @default.
- W2111761016 cites W2038382302 @default.
- W2111761016 cites W2039260613 @default.
- W2111761016 cites W2044821232 @default.
- W2111761016 cites W2052787700 @default.
- W2111761016 cites W2055035166 @default.
- W2111761016 cites W2062229313 @default.
- W2111761016 cites W2063802268 @default.
- W2111761016 cites W2067709564 @default.
- W2111761016 cites W2070098741 @default.
- W2111761016 cites W2078206871 @default.
- W2111761016 cites W2079481850 @default.
- W2111761016 cites W2086723409 @default.
- W2111761016 cites W2087642255 @default.
- W2111761016 cites W2097061517 @default.
- W2111761016 cites W2101015806 @default.
- W2111761016 cites W2106823063 @default.
- W2111761016 cites W2113123117 @default.
- W2111761016 cites W2123698136 @default.
- W2111761016 cites W2123994740 @default.
- W2111761016 cites W2127522069 @default.
- W2111761016 cites W2127525287 @default.
- W2111761016 cites W2131973068 @default.
- W2111761016 cites W2135864113 @default.
- W2111761016 cites W2137742067 @default.
- W2111761016 cites W2139937737 @default.
- W2111761016 cites W2154068227 @default.
- W2111761016 cites W2161481747 @default.
- W2111761016 cites W2165797048 @default.
- W2111761016 cites W2166522915 @default.
- W2111761016 cites W2168194514 @default.
- W2111761016 cites W2171365509 @default.
- W2111761016 cites W2171745766 @default.
- W2111761016 cites W2172000053 @default.
- W2111761016 cites W2322121630 @default.
- W2111761016 cites W4246250719 @default.
- W2111761016 doi "https://doi.org/10.1097/mcc.0b013e328332f6cf" @default.
- W2111761016 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19829106" @default.
- W2111761016 hasPublicationYear "2009" @default.
- W2111761016 type Work @default.
- W2111761016 sameAs 2111761016 @default.
- W2111761016 citedByCount "133" @default.
- W2111761016 countsByYear W21117610162012 @default.
- W2111761016 countsByYear W21117610162013 @default.
- W2111761016 countsByYear W21117610162014 @default.
- W2111761016 countsByYear W21117610162015 @default.
- W2111761016 countsByYear W21117610162016 @default.
- W2111761016 countsByYear W21117610162017 @default.
- W2111761016 countsByYear W21117610162018 @default.
- W2111761016 countsByYear W21117610162019 @default.
- W2111761016 countsByYear W21117610162020 @default.
- W2111761016 countsByYear W21117610162021 @default.
- W2111761016 countsByYear W21117610162022 @default.
- W2111761016 countsByYear W21117610162023 @default.
- W2111761016 crossrefType "journal-article" @default.
- W2111761016 hasAuthorship W2111761016A5040713731 @default.
- W2111761016 hasAuthorship W2111761016A5050936569 @default.
- W2111761016 hasAuthorship W2111761016A5057342507 @default.
- W2111761016 hasAuthorship W2111761016A5091348002 @default.
- W2111761016 hasConcept C126322002 @default.
- W2111761016 hasConcept C12722491 @default.
- W2111761016 hasConcept C178790620 @default.
- W2111761016 hasConcept C185592680 @default.
- W2111761016 hasConcept C2780091579 @default.
- W2111761016 hasConcept C2780472472 @default.
- W2111761016 hasConcept C2780972559 @default.
- W2111761016 hasConcept C519581460 @default.
- W2111761016 hasConcept C540031477 @default.