Matches in SemOpenAlex for { <https://semopenalex.org/work/W2111796749> ?p ?o ?g. }
- W2111796749 abstract "Cystatins are reversible, tightly binding inhibitors of cysteine proteases. Filarial cystatins have been ascribed immunomodulatory properties and have been implicated in protective immunity. To continue exploration of this potential, here we have determined the sequence, structure and genomic organization of the cystatin gene locus of A. viteae. The gene is composed of 4 exons separated by 3 introns and spans approximately 2 kb of genomic DNA. The upstream genomic sequence contains transcriptional factor binding sites such as AP-1 and NF-Y, an inverted CCAAT sequence, and a TATA box. To investigate sites of cystatin expression, Caenorhabditis elegans worms were transformed by microinjection with the putative promoter region and the first exon of the A. viteae cystatin gene fused to the reporter GFP. In transgenic worms fluorescence was observed in the pharyngeal and rectal gland cells suggesting that cystatin is secreted. Additionally, A. viteae cystatin was expressed in C. elegans to explore its potential as an expression system for filarial genes." @default.
- W2111796749 created "2016-06-24" @default.
- W2111796749 creator A5013424053 @default.
- W2111796749 creator A5041152749 @default.
- W2111796749 creator A5045813441 @default.
- W2111796749 creator A5058922118 @default.
- W2111796749 creator A5063804306 @default.
- W2111796749 creator A5081576727 @default.
- W2111796749 date "2005-08-09" @default.
- W2111796749 modified "2023-09-25" @default.
- W2111796749 title "Studies on Acanthocheilonema viteae cystatin: Genomic organization, promoter studies and expression in Caenorhabditis elegans" @default.
- W2111796749 cites W1505828408 @default.
- W2111796749 cites W1530238672 @default.
- W2111796749 cites W1581412826 @default.
- W2111796749 cites W1944127002 @default.
- W2111796749 cites W1965051773 @default.
- W2111796749 cites W1969709439 @default.
- W2111796749 cites W1973728643 @default.
- W2111796749 cites W1983426701 @default.
- W2111796749 cites W1986117681 @default.
- W2111796749 cites W1993608017 @default.
- W2111796749 cites W1994989080 @default.
- W2111796749 cites W2001693838 @default.
- W2111796749 cites W2004070693 @default.
- W2111796749 cites W2018289835 @default.
- W2111796749 cites W2021509498 @default.
- W2111796749 cites W2027872459 @default.
- W2111796749 cites W2033130744 @default.
- W2111796749 cites W2037795676 @default.
- W2111796749 cites W2038776199 @default.
- W2111796749 cites W2046658013 @default.
- W2111796749 cites W2056553319 @default.
- W2111796749 cites W2068691406 @default.
- W2111796749 cites W2070953302 @default.
- W2111796749 cites W2071689338 @default.
- W2111796749 cites W2101108802 @default.
- W2111796749 cites W2101977076 @default.
- W2111796749 cites W2106742994 @default.
- W2111796749 cites W2109160513 @default.
- W2111796749 cites W2131700621 @default.
- W2111796749 cites W2135449563 @default.
- W2111796749 cites W2139112371 @default.
- W2111796749 cites W2157772863 @default.
- W2111796749 cites W2159033700 @default.
- W2111796749 cites W2169983473 @default.
- W2111796749 cites W2186585598 @default.
- W2111796749 cites W2394860713 @default.
- W2111796749 cites W4212767648 @default.
- W2111796749 cites W4301119686 @default.
- W2111796749 doi "https://doi.org/10.1186/1475-2883-4-9" @default.
- W2111796749 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1187909" @default.
- W2111796749 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16091144" @default.
- W2111796749 hasPublicationYear "2005" @default.
- W2111796749 type Work @default.
- W2111796749 sameAs 2111796749 @default.
- W2111796749 citedByCount "4" @default.
- W2111796749 countsByYear W21117967492014 @default.
- W2111796749 crossrefType "journal-article" @default.
- W2111796749 hasAuthorship W2111796749A5013424053 @default.
- W2111796749 hasAuthorship W2111796749A5041152749 @default.
- W2111796749 hasAuthorship W2111796749A5045813441 @default.
- W2111796749 hasAuthorship W2111796749A5058922118 @default.
- W2111796749 hasAuthorship W2111796749A5063804306 @default.
- W2111796749 hasAuthorship W2111796749A5081576727 @default.
- W2111796749 hasBestOaLocation W21117967491 @default.
- W2111796749 hasConcept C104317684 @default.
- W2111796749 hasConcept C141231307 @default.
- W2111796749 hasConcept C153911025 @default.
- W2111796749 hasConcept C159641895 @default.
- W2111796749 hasConcept C17757408 @default.
- W2111796749 hasConcept C2778873838 @default.
- W2111796749 hasConcept C2778944004 @default.
- W2111796749 hasConcept C2779548226 @default.
- W2111796749 hasConcept C2780412452 @default.
- W2111796749 hasConcept C36823959 @default.
- W2111796749 hasConcept C54355233 @default.
- W2111796749 hasConcept C55493867 @default.
- W2111796749 hasConcept C86803240 @default.
- W2111796749 hasConceptScore W2111796749C104317684 @default.
- W2111796749 hasConceptScore W2111796749C141231307 @default.
- W2111796749 hasConceptScore W2111796749C153911025 @default.
- W2111796749 hasConceptScore W2111796749C159641895 @default.
- W2111796749 hasConceptScore W2111796749C17757408 @default.
- W2111796749 hasConceptScore W2111796749C2778873838 @default.
- W2111796749 hasConceptScore W2111796749C2778944004 @default.
- W2111796749 hasConceptScore W2111796749C2779548226 @default.
- W2111796749 hasConceptScore W2111796749C2780412452 @default.
- W2111796749 hasConceptScore W2111796749C36823959 @default.
- W2111796749 hasConceptScore W2111796749C54355233 @default.
- W2111796749 hasConceptScore W2111796749C55493867 @default.
- W2111796749 hasConceptScore W2111796749C86803240 @default.
- W2111796749 hasIssue "1" @default.
- W2111796749 hasLocation W21117967491 @default.
- W2111796749 hasLocation W21117967492 @default.
- W2111796749 hasLocation W21117967493 @default.
- W2111796749 hasLocation W21117967494 @default.
- W2111796749 hasOpenAccess W2111796749 @default.
- W2111796749 hasPrimaryLocation W21117967491 @default.
- W2111796749 hasRelatedWork W1977245762 @default.
- W2111796749 hasRelatedWork W2035919360 @default.