FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2111864152> ?p ?o ?g. }

• W2111864152 endingPage "751" @default.
• W2111864152 startingPage "738" @default.
• W2111864152 abstract "The role of individual H-2I subregion determinants in the activation of H-2I alloantigen-primed mixed leukocyte response suppressor T cells (MLR Ts), as well as their possible expression on stimulator cells required to trigger primed H-2K- or D-specific MLR Ts, was addressed in these studies. Both genetic and serologic studies demonstrated that MLR Ts potentially primed to alloantigens encoded by the entire H-2I region were triggered to MLR Ts factor production only by stimulator cells bearing the priming I-J and/or I-C, but not I-A or I-E alloantigens. The relevant I-J and I-C determinants were demonstrated on a single antigen-presenting cell population that is used in common by independent I-J-specific and I-C-specific MLR Ts. Unexpectedly, the stimulator cell population necessary to trigger MLR Ts primed to class I H-2K or D alloantigens expressed not only the priming class I determinant, but in addition, I-C alloantigens syngeneic with the MLR Ts haplotype. Stimulator populations bearing the appropriate H-2K or D alloantigen but serologically depleted of I-C+ cells or genetically constructed to display MLR Ts-disparate I-C determinants were ineffective stimulators of class I antigen-primed MLR Ts. Thus these data suggest that as allogeneic determinants, I-J- and I-C-encoded molecules are together the major triggering elements for MLR Ts primed to disparate H-2I region determinants. In addition, self-I-C molecule recognition appears to constitute an important feature of the triggering, and by implication, priming process of H-2 class I antigen-specific Ts cells." @default.
• W2111864152 created "2016-06-24" @default.
• W2111864152 creator A5054307423 @default.
• W2111864152 date "1983-09-01" @default.
• W2111864152 modified "2023-10-18" @default.
• W2111864152 title "Regulatory mechanisms in cell-mediated immune responses. Role of I-J and I-C determinants in the activation of H-2I and H-2K/D alloantigen-specific suppressor T cells." @default.
• W2111864152 cites W1511026723 @default.
• W2111864152 cites W1537573377 @default.
• W2111864152 cites W1542049240 @default.
• W2111864152 cites W1550755687 @default.
• W2111864152 cites W1552347252 @default.
• W2111864152 cites W1556608090 @default.
• W2111864152 cites W1565918259 @default.
• W2111864152 cites W1576426340 @default.
• W2111864152 cites W1594898305 @default.
• W2111864152 cites W1604831773 @default.
• W2111864152 cites W1658245484 @default.
• W2111864152 cites W1916729565 @default.
• W2111864152 cites W1977904979 @default.
• W2111864152 cites W1998167311 @default.
• W2111864152 cites W2005770085 @default.
• W2111864152 cites W2013209874 @default.
• W2111864152 cites W2021455174 @default.
• W2111864152 cites W2037038285 @default.
• W2111864152 cites W2040001939 @default.
• W2111864152 cites W2060736493 @default.
• W2111864152 cites W2061429475 @default.
• W2111864152 cites W2071914447 @default.
• W2111864152 cites W2074721833 @default.
• W2111864152 cites W2076600235 @default.
• W2111864152 cites W2092262156 @default.
• W2111864152 cites W2104408228 @default.
• W2111864152 cites W2112999151 @default.
• W2111864152 cites W2113333633 @default.
• W2111864152 cites W2115608169 @default.
• W2111864152 cites W2116891884 @default.
• W2111864152 cites W2117331749 @default.
• W2111864152 cites W2129721227 @default.
• W2111864152 cites W2135349882 @default.
• W2111864152 cites W2144346900 @default.
• W2111864152 cites W2161455453 @default.
• W2111864152 cites W2164136009 @default.
• W2111864152 cites W2167994162 @default.
• W2111864152 cites W2402239796 @default.
• W2111864152 doi "https://doi.org/10.1084/jem.158.3.738" @default.
• W2111864152 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2187109" @default.
• W2111864152 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6193232" @default.
• W2111864152 hasPublicationYear "1983" @default.
• W2111864152 type Work @default.
• W2111864152 sameAs 2111864152 @default.
• W2111864152 citedByCount "8" @default.
• W2111864152 crossrefType "journal-article" @default.
• W2111864152 hasAuthorship W2111864152A5054307423 @default.
• W2111864152 hasBestOaLocation W21118641521 @default.
• W2111864152 hasConcept C100701293 @default.
• W2111864152 hasConcept C104317684 @default.
• W2111864152 hasConcept C147483822 @default.
• W2111864152 hasConcept C153911025 @default.
• W2111864152 hasConcept C179185449 @default.
• W2111864152 hasConcept C203014093 @default.
• W2111864152 hasConcept C2776090121 @default.
• W2111864152 hasConcept C2778740727 @default.
• W2111864152 hasConcept C2908647359 @default.
• W2111864152 hasConcept C54355233 @default.
• W2111864152 hasConcept C59822182 @default.
• W2111864152 hasConcept C71924100 @default.
• W2111864152 hasConcept C81444415 @default.
• W2111864152 hasConcept C86803240 @default.
• W2111864152 hasConcept C8891405 @default.
• W2111864152 hasConcept C99454951 @default.
• W2111864152 hasConceptScore W2111864152C100701293 @default.
• W2111864152 hasConceptScore W2111864152C104317684 @default.
• W2111864152 hasConceptScore W2111864152C147483822 @default.
• W2111864152 hasConceptScore W2111864152C153911025 @default.
• W2111864152 hasConceptScore W2111864152C179185449 @default.
• W2111864152 hasConceptScore W2111864152C203014093 @default.
• W2111864152 hasConceptScore W2111864152C2776090121 @default.
• W2111864152 hasConceptScore W2111864152C2778740727 @default.
• W2111864152 hasConceptScore W2111864152C2908647359 @default.
• W2111864152 hasConceptScore W2111864152C54355233 @default.
• W2111864152 hasConceptScore W2111864152C59822182 @default.
• W2111864152 hasConceptScore W2111864152C71924100 @default.
• W2111864152 hasConceptScore W2111864152C81444415 @default.
• W2111864152 hasConceptScore W2111864152C86803240 @default.
• W2111864152 hasConceptScore W2111864152C8891405 @default.
• W2111864152 hasConceptScore W2111864152C99454951 @default.
• W2111864152 hasIssue "3" @default.
• W2111864152 hasLocation W21118641521 @default.
• W2111864152 hasLocation W21118641522 @default.
• W2111864152 hasLocation W21118641523 @default.
• W2111864152 hasLocation W21118641524 @default.
• W2111864152 hasOpenAccess W2111864152 @default.
• W2111864152 hasPrimaryLocation W21118641521 @default.
• W2111864152 hasRelatedWork W144576309 @default.
• W2111864152 hasRelatedWork W1583487173 @default.
• W2111864152 hasRelatedWork W2022517847 @default.
• W2111864152 hasRelatedWork W2171223656 @default.
• W2111864152 hasRelatedWork W2220102944 @default.

• next