FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2111923310> ?p ?o ?g. }

• W2111923310 endingPage "e97399" @default.
• W2111923310 startingPage "e97399" @default.
• W2111923310 abstract "Myostatin is essential for proper regulation of myogenesis, and inactivation of Myostatin results in muscle hypertrophy. Here, we identified an unexpected mutation in the myostatin gene which is almost fixed in Blonde d'Aquitaine cattle. In skeletal muscle, the mutant allele was highly expressed leading to an abnormal transcript consisting of a 41-bp inclusion and premature termination codons and to residual levels of a correctly spliced transcript. This expression pattern, caused by a leaky intronic mutation with regard to spliceosome activity and its apparent stability with regard to surveillance mechanisms, could contribute to the moderate muscle hypertrophy in this cattle breed. This finding is of importance for genetic counseling for meat quantity and quality in livestock production and possibly to manipulate myostatin pre-mRNA in human muscle diseases." @default.
• W2111923310 created "2016-06-24" @default.
• W2111923310 creator A5014622245 @default.
• W2111923310 creator A5034400121 @default.
• W2111923310 creator A5062156051 @default.
• W2111923310 creator A5065393354 @default.
• W2111923310 date "2014-05-14" @default.
• W2111923310 modified "2023-10-12" @default.
• W2111923310 title "Deep Intronic Mutation and Pseudo Exon Activation as a Novel Muscular Hypertrophy Modifier in Cattle" @default.
• W2111923310 cites W1793391779 @default.
• W2111923310 cites W1971189666 @default.
• W2111923310 cites W1986469118 @default.
• W2111923310 cites W2025463260 @default.
• W2111923310 cites W2034074403 @default.
• W2111923310 cites W2041487644 @default.
• W2111923310 cites W2053079324 @default.
• W2111923310 cites W2055789788 @default.
• W2111923310 cites W2061645846 @default.
• W2111923310 cites W2087034573 @default.
• W2111923310 cites W2099927467 @default.
• W2111923310 cites W2102638170 @default.
• W2111923310 cites W2105608476 @default.
• W2111923310 cites W2120461242 @default.
• W2111923310 cites W2122594291 @default.
• W2111923310 cites W2130122556 @default.
• W2111923310 cites W2134406094 @default.
• W2111923310 cites W2138089538 @default.
• W2111923310 cites W2145274091 @default.
• W2111923310 cites W2149993139 @default.
• W2111923310 cites W2152128819 @default.
• W2111923310 cites W2165868509 @default.
• W2111923310 cites W2166877291 @default.
• W2111923310 cites W2166947475 @default.
• W2111923310 cites W2312522445 @default.
• W2111923310 doi "https://doi.org/10.1371/journal.pone.0097399" @default.
• W2111923310 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4020855" @default.
• W2111923310 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24827585" @default.
• W2111923310 hasPublicationYear "2014" @default.
• W2111923310 type Work @default.
• W2111923310 sameAs 2111923310 @default.
• W2111923310 citedByCount "12" @default.
• W2111923310 countsByYear W21119233102015 @default.
• W2111923310 countsByYear W21119233102016 @default.
• W2111923310 countsByYear W21119233102017 @default.
• W2111923310 countsByYear W21119233102018 @default.
• W2111923310 countsByYear W21119233102020 @default.
• W2111923310 countsByYear W21119233102021 @default.
• W2111923310 countsByYear W21119233102022 @default.
• W2111923310 countsByYear W21119233102023 @default.
• W2111923310 crossrefType "journal-article" @default.
• W2111923310 hasAuthorship W2111923310A5014622245 @default.
• W2111923310 hasAuthorship W2111923310A5034400121 @default.
• W2111923310 hasAuthorship W2111923310A5062156051 @default.
• W2111923310 hasAuthorship W2111923310A5065393354 @default.
• W2111923310 hasBestOaLocation W21119233101 @default.
• W2111923310 hasConcept C104317684 @default.
• W2111923310 hasConcept C134018914 @default.
• W2111923310 hasConcept C167414201 @default.
• W2111923310 hasConcept C194583182 @default.
• W2111923310 hasConcept C2777488582 @default.
• W2111923310 hasConcept C2778776201 @default.
• W2111923310 hasConcept C36823959 @default.
• W2111923310 hasConcept C3763915 @default.
• W2111923310 hasConcept C501734568 @default.
• W2111923310 hasConcept C54355233 @default.
• W2111923310 hasConcept C86803240 @default.
• W2111923310 hasConceptScore W2111923310C104317684 @default.
• W2111923310 hasConceptScore W2111923310C134018914 @default.
• W2111923310 hasConceptScore W2111923310C167414201 @default.
• W2111923310 hasConceptScore W2111923310C194583182 @default.
• W2111923310 hasConceptScore W2111923310C2777488582 @default.
• W2111923310 hasConceptScore W2111923310C2778776201 @default.
• W2111923310 hasConceptScore W2111923310C36823959 @default.
• W2111923310 hasConceptScore W2111923310C3763915 @default.
• W2111923310 hasConceptScore W2111923310C501734568 @default.
• W2111923310 hasConceptScore W2111923310C54355233 @default.
• W2111923310 hasConceptScore W2111923310C86803240 @default.
• W2111923310 hasIssue "5" @default.
• W2111923310 hasLocation W21119233101 @default.
• W2111923310 hasLocation W21119233102 @default.
• W2111923310 hasLocation W21119233103 @default.
• W2111923310 hasLocation W21119233104 @default.
• W2111923310 hasLocation W21119233105 @default.
• W2111923310 hasLocation W21119233106 @default.
• W2111923310 hasLocation W21119233107 @default.
• W2111923310 hasLocation W21119233108 @default.
• W2111923310 hasOpenAccess W2111923310 @default.
• W2111923310 hasPrimaryLocation W21119233101 @default.
• W2111923310 hasRelatedWork W1689318462 @default.
• W2111923310 hasRelatedWork W1973536277 @default.
• W2111923310 hasRelatedWork W1978278774 @default.
• W2111923310 hasRelatedWork W1982422465 @default.
• W2111923310 hasRelatedWork W1991499991 @default.
• W2111923310 hasRelatedWork W2018683003 @default.
• W2111923310 hasRelatedWork W2153881525 @default.
• W2111923310 hasRelatedWork W2166665499 @default.
• W2111923310 hasRelatedWork W2169876318 @default.
• W2111923310 hasRelatedWork W857489826 @default.

• next