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• W2111960652 abstract "Based on the well known biological versatility of the imidazoline nucleus, we prepared the novel derivatives 3a–k inspired by 2-BFI scaffold to assess imidazoline molecules as D2-like dopamine receptor ligands. Conservative chemical modifications of the lead structure, such as the introduction of an hydroxy group in the aromatic ring alone or associated with N-benzyl substitution, provided partial (3f) or nearly full (3e and 3h) agonists, all endowed with D2-like potency comparable to that of dopamine." @default.
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• W2111960652 date "2010-10-01" @default.
• W2111960652 modified "2023-10-01" @default.
• W2111960652 title "Novel imidazoline compounds as partial or full agonists of D2-like dopamine receptors inspired by I2-imidazoline binding sites ligand 2-BFI" @default.
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• W2111960652 doi "https://doi.org/10.1016/j.bmc.2010.08.005" @default.
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