FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2111980811> ?p ?o ?g. }

• W2111980811 endingPage "150" @default.
• W2111980811 startingPage "145" @default.
• W2111980811 abstract "EMR2 is a human myeloid-restricted member of the EGF-TM7 receptor family that contains a highly conserved G protein-coupled receptor proteolysis site (GPS) in the membrane-proximal region. Here the post-translational proteolytic cleavage of EMR2 at GPS was investigated. We show the cleavage occurs at Leu517-Ser518 and is independent of the transmembrane domains. The non-covalent association of the resulting extracellular alpha-subunit and transmembrane beta-subunit requires a minimum of eight amino acids in the beta-subunit. The GPS motif is necessary, but not sufficient for receptor cleavage, which requires the entire extracellular stalk. Thus, an alternatively spliced EMR2 isoform with a truncated stalk fails to undergo proteolytic cleavage. Alternative splicing therefore provides a means to regulate GPS cleavage, producing receptors with two distinct structures." @default.
• W2111980811 created "2016-06-24" @default.
• W2111980811 creator A5003712288 @default.
• W2111980811 creator A5034426271 @default.
• W2111980811 creator A5059582877 @default.
• W2111980811 creator A5060136306 @default.
• W2111980811 creator A5060388462 @default.
• W2111980811 creator A5061586072 @default.
• W2111980811 date "2003-06-21" @default.
• W2111980811 modified "2023-10-16" @default.
• W2111980811 title "Proteolytic cleavage of the EMR2 receptor requires both the extracellular stalk and the GPS motif" @default.
• W2111980811 cites W1966354110 @default.
• W2111980811 cites W1983026762 @default.
• W2111980811 cites W1984615286 @default.
• W2111980811 cites W1987157213 @default.
• W2111980811 cites W1990249568 @default.
• W2111980811 cites W2001406742 @default.
• W2111980811 cites W2042965761 @default.
• W2111980811 cites W2045268402 @default.
• W2111980811 cites W2053901337 @default.
• W2111980811 cites W2066633592 @default.
• W2111980811 cites W2070488197 @default.
• W2111980811 cites W2071290544 @default.
• W2111980811 cites W2080560131 @default.
• W2111980811 cites W2108743747 @default.
• W2111980811 cites W2112124618 @default.
• W2111980811 cites W2116194397 @default.
• W2111980811 cites W2139780190 @default.
• W2111980811 cites W2140148673 @default.
• W2111980811 cites W2140858431 @default.
• W2111980811 cites W2141181488 @default.
• W2111980811 cites W2147210417 @default.
• W2111980811 cites W2154643490 @default.
• W2111980811 doi "https://doi.org/10.1016/s0014-5793(03)00695-1" @default.
• W2111980811 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12860403" @default.
• W2111980811 hasPublicationYear "2003" @default.
• W2111980811 type Work @default.
• W2111980811 sameAs 2111980811 @default.
• W2111980811 citedByCount "60" @default.
• W2111980811 countsByYear W21119808112012 @default.
• W2111980811 countsByYear W21119808112013 @default.
• W2111980811 countsByYear W21119808112014 @default.
• W2111980811 countsByYear W21119808112015 @default.
• W2111980811 countsByYear W21119808112016 @default.
• W2111980811 countsByYear W21119808112017 @default.
• W2111980811 countsByYear W21119808112018 @default.
• W2111980811 countsByYear W21119808112019 @default.
• W2111980811 countsByYear W21119808112020 @default.
• W2111980811 countsByYear W21119808112021 @default.
• W2111980811 countsByYear W21119808112022 @default.
• W2111980811 countsByYear W21119808112023 @default.
• W2111980811 crossrefType "journal-article" @default.
• W2111980811 hasAuthorship W2111980811A5003712288 @default.
• W2111980811 hasAuthorship W2111980811A5034426271 @default.
• W2111980811 hasAuthorship W2111980811A5059582877 @default.
• W2111980811 hasAuthorship W2111980811A5060136306 @default.
• W2111980811 hasAuthorship W2111980811A5060388462 @default.
• W2111980811 hasAuthorship W2111980811A5061586072 @default.
• W2111980811 hasConcept C104292427 @default.
• W2111980811 hasConcept C104317684 @default.
• W2111980811 hasConcept C105580179 @default.
• W2111980811 hasConcept C118892022 @default.
• W2111980811 hasConcept C133672593 @default.
• W2111980811 hasConcept C151730666 @default.
• W2111980811 hasConcept C170493617 @default.
• W2111980811 hasConcept C175156509 @default.
• W2111980811 hasConcept C181199279 @default.
• W2111980811 hasConcept C185592680 @default.
• W2111980811 hasConcept C24530287 @default.
• W2111980811 hasConcept C2781307694 @default.
• W2111980811 hasConcept C28406088 @default.
• W2111980811 hasConcept C43369102 @default.
• W2111980811 hasConcept C55493867 @default.
• W2111980811 hasConcept C86803240 @default.
• W2111980811 hasConcept C95444343 @default.
• W2111980811 hasConceptScore W2111980811C104292427 @default.
• W2111980811 hasConceptScore W2111980811C104317684 @default.
• W2111980811 hasConceptScore W2111980811C105580179 @default.
• W2111980811 hasConceptScore W2111980811C118892022 @default.
• W2111980811 hasConceptScore W2111980811C133672593 @default.
• W2111980811 hasConceptScore W2111980811C151730666 @default.
• W2111980811 hasConceptScore W2111980811C170493617 @default.
• W2111980811 hasConceptScore W2111980811C175156509 @default.
• W2111980811 hasConceptScore W2111980811C181199279 @default.
• W2111980811 hasConceptScore W2111980811C185592680 @default.
• W2111980811 hasConceptScore W2111980811C24530287 @default.
• W2111980811 hasConceptScore W2111980811C2781307694 @default.
• W2111980811 hasConceptScore W2111980811C28406088 @default.
• W2111980811 hasConceptScore W2111980811C43369102 @default.
• W2111980811 hasConceptScore W2111980811C55493867 @default.
• W2111980811 hasConceptScore W2111980811C86803240 @default.
• W2111980811 hasConceptScore W2111980811C95444343 @default.
• W2111980811 hasIssue "1-3" @default.
• W2111980811 hasLocation W21119808111 @default.
• W2111980811 hasLocation W21119808112 @default.
• W2111980811 hasOpenAccess W2111980811 @default.
• W2111980811 hasPrimaryLocation W21119808111 @default.
• W2111980811 hasRelatedWork W111980633 @default.

• next