Matches in SemOpenAlex for { <https://semopenalex.org/work/W2112046386> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2112046386 endingPage "825" @default.
- W2112046386 startingPage "818" @default.
- W2112046386 abstract "Two cloned derivatives of the Kc cell line of Drosophila were shown to produce DOPA decarboxylase following administration of the steroid moulting hormone 20-hydroxyecdysone. In the continuous presence of the hormone at a concentration of 2 X 10(-7) M, DOPA decarboxylase activity first appeared between 48 and 72 h. Because of this lag, the tissue culture system promises to serve as a useful model for those in vivo situations where increases in the hormone titre precede increases in DOPA decarboxylase activity. In clone 7C4, after maximal enzyme activity was achieved at 144 h, the enzyme activity per cell decreased as the cells resumed division following the hormone-induced division arrest. In clone 7E10, cell division never resumed in the presence of 20-hydroxyecdysone and DOPA decarboxylase activity per cell increased continuously from the time it first appeared. When line 7E10 was exposed to a 6-h pulse of the steroid, enzyme activity appeared about 18 h earlier than in the presence of continuous hormone and, further, the cells were released from division arrest. Enzyme activity per cell then declined from an early 96-h maximum. The enzyme produced by the cell lines was immunologically distinct from the enzyme produced in vivo and ion-exchange column chromatography resolved the enzyme from cells and intact organisms into two species.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
- W2112046386 created "2016-06-24" @default.
- W2112046386 creator A5012280368 @default.
- W2112046386 creator A5034836695 @default.
- W2112046386 creator A5066422597 @default.
- W2112046386 creator A5067029467 @default.
- W2112046386 date "1983-07-01" @default.
- W2112046386 modified "2023-09-26" @default.
- W2112046386 title "A novel form of DOPA decarboxylase produced in Drosophila cells in response to 20-hydroxyecdysone" @default.
- W2112046386 doi "https://doi.org/10.1139/o83-104" @default.
- W2112046386 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6194869" @default.
- W2112046386 hasPublicationYear "1983" @default.
- W2112046386 type Work @default.
- W2112046386 sameAs 2112046386 @default.
- W2112046386 citedByCount "18" @default.
- W2112046386 countsByYear W21120463862018 @default.
- W2112046386 crossrefType "journal-article" @default.
- W2112046386 hasAuthorship W2112046386A5012280368 @default.
- W2112046386 hasAuthorship W2112046386A5034836695 @default.
- W2112046386 hasAuthorship W2112046386A5066422597 @default.
- W2112046386 hasAuthorship W2112046386A5067029467 @default.
- W2112046386 hasConcept C126322002 @default.
- W2112046386 hasConcept C134018914 @default.
- W2112046386 hasConcept C1491633281 @default.
- W2112046386 hasConcept C181199279 @default.
- W2112046386 hasConcept C207001950 @default.
- W2112046386 hasConcept C2776888042 @default.
- W2112046386 hasConcept C2779324052 @default.
- W2112046386 hasConcept C2780484280 @default.
- W2112046386 hasConcept C28212737 @default.
- W2112046386 hasConcept C54355233 @default.
- W2112046386 hasConcept C552990157 @default.
- W2112046386 hasConcept C55493867 @default.
- W2112046386 hasConcept C58824617 @default.
- W2112046386 hasConcept C71315377 @default.
- W2112046386 hasConcept C71924100 @default.
- W2112046386 hasConcept C81089528 @default.
- W2112046386 hasConcept C81885089 @default.
- W2112046386 hasConcept C85813293 @default.
- W2112046386 hasConcept C86803240 @default.
- W2112046386 hasConceptScore W2112046386C126322002 @default.
- W2112046386 hasConceptScore W2112046386C134018914 @default.
- W2112046386 hasConceptScore W2112046386C1491633281 @default.
- W2112046386 hasConceptScore W2112046386C181199279 @default.
- W2112046386 hasConceptScore W2112046386C207001950 @default.
- W2112046386 hasConceptScore W2112046386C2776888042 @default.
- W2112046386 hasConceptScore W2112046386C2779324052 @default.
- W2112046386 hasConceptScore W2112046386C2780484280 @default.
- W2112046386 hasConceptScore W2112046386C28212737 @default.
- W2112046386 hasConceptScore W2112046386C54355233 @default.
- W2112046386 hasConceptScore W2112046386C552990157 @default.
- W2112046386 hasConceptScore W2112046386C55493867 @default.
- W2112046386 hasConceptScore W2112046386C58824617 @default.
- W2112046386 hasConceptScore W2112046386C71315377 @default.
- W2112046386 hasConceptScore W2112046386C71924100 @default.
- W2112046386 hasConceptScore W2112046386C81089528 @default.
- W2112046386 hasConceptScore W2112046386C81885089 @default.
- W2112046386 hasConceptScore W2112046386C85813293 @default.
- W2112046386 hasConceptScore W2112046386C86803240 @default.
- W2112046386 hasIssue "7" @default.
- W2112046386 hasLocation W21120463861 @default.
- W2112046386 hasLocation W21120463862 @default.
- W2112046386 hasOpenAccess W2112046386 @default.
- W2112046386 hasPrimaryLocation W21120463861 @default.
- W2112046386 hasRelatedWork W1981953352 @default.
- W2112046386 hasRelatedWork W1992423160 @default.
- W2112046386 hasRelatedWork W2031303660 @default.
- W2112046386 hasRelatedWork W2053073845 @default.
- W2112046386 hasRelatedWork W2105129031 @default.
- W2112046386 hasRelatedWork W2108839789 @default.
- W2112046386 hasRelatedWork W2111456652 @default.
- W2112046386 hasRelatedWork W2112046386 @default.
- W2112046386 hasRelatedWork W2126669650 @default.
- W2112046386 hasRelatedWork W2380989154 @default.
- W2112046386 hasVolume "61" @default.
- W2112046386 isParatext "false" @default.
- W2112046386 isRetracted "false" @default.
- W2112046386 magId "2112046386" @default.
- W2112046386 workType "article" @default.