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- W2112061265 abstract "A very rare case of a menstruating infertile woman with isolated luteinizing hormone (LH) hypergonadotrophin-aemia is presented. There were no signs indicating the presence of a pituitary microadenoma, and LH had normal bioactivity and normal molecular weight Likewise, no mutation was detected in the coding region of the LH β-chain gene. In a non-stimulated cycle and a clomiphene citrate cycle, the patient developed an unruptured cyst The patient ovulated and conceived twice following the addition of human chorionic gonadotrophin. A partial resistance at the ovarian LH receptor site, perhaps caused by a mutation, is a possible explanation for these findings. Another possibility is a malfunction in the signal transduc-tion system of LH beyond the receptor level." @default.
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- W2112061265 date "1996-01-01" @default.
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- W2112061265 title "A case of hypergonadotrophinaemia associated with very high isolated concentrations of immunologically and biologically active lutemizing hormone" @default.
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- W2112061265 doi "https://doi.org/10.1093/oxfordjournals.humrep.a019036" @default.
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