FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2112154893> ?p ?o ?g. }

• W2112154893 endingPage "981" @default.
• W2112154893 startingPage "972" @default.
• W2112154893 abstract "Background Transfusions are the primary therapy for thalassemia but have significant cumulative risks. In 2004, the Centers for Disease Control and Prevention (CDC) established a national blood safety monitoring program for thalassemia. This report summarizes the population and their previous nonimmune and immune transfusion complications. Study Design and Methods The CDC Thalassemia Blood Safety Network is a consortium of centers longitudinally following patients. Enrollment occurred from 2004 through 2012. Demographics, transfusion history, infectious exposures, and transfusion and nontransfusion complications were summarized. Logistic regression analyses of factors associated with allo- and autoimmunization were employed. Results The race/ethnicity of these 407 thalassemia patients was predominantly Asian or Caucasian. The mean ± SD age was 22.3 ± 13.2 years and patients had received a mean ± SD total number of 149 ± 103.4 units of red blood cells (RBCs). Multiorgan dysfunction was common despite chelation. Twenty-four percent of transfused patients had previous exposure to possible transfusion-associated pathogens including one case of babesia. As 27% were immigrants, the infection source cannot be unequivocally linked to transfusion. Transfusion reactions occurred in 48%, including allergic, febrile, and hemolytic; 19% were alloimmunized. Common antigens were E, Kell, and C. Years of transfusion was the strongest predictor of alloimmunization. Autoantibodies occurred in 6.5% and were associated with alloimmunization (p < 0.0001). Local institutional policies, not patient characteristics, were major determinants of blood preparation and transfusion practices. Conclusion Hemosiderosis, transfusion reactions, and infections continue to be major problems in thalassemia. New pathogens were noted. National guidelines for RBC phenotyping and preparation are needed to decrease transfusion-related morbidity." @default.
• W2112154893 created "2016-06-24" @default.
• W2112154893 creator A5003499192 @default.
• W2112154893 creator A5032872264 @default.
• W2112154893 creator A5038535078 @default.
• W2112154893 creator A5042878817 @default.
• W2112154893 creator A5043948649 @default.
• W2112154893 creator A5047043925 @default.
• W2112154893 creator A5056946591 @default.
• W2112154893 creator A5058608098 @default.
• W2112154893 creator A5071684654 @default.
• W2112154893 creator A5072631536 @default.
• W2112154893 creator A5086688631 @default.
• W2112154893 date "2013-07-25" @default.
• W2112154893 modified "2023-10-01" @default.
• W2112154893 title "Transfusion complications in thalassemia patients: a report from the Centers for Disease Control and Prevention (CME)" @default.
• W2112154893 cites W145680385 @default.
• W2112154893 cites W1503869740 @default.
• W2112154893 cites W1557711811 @default.
• W2112154893 cites W1601004541 @default.
• W2112154893 cites W1751167626 @default.
• W2112154893 cites W1864230249 @default.
• W2112154893 cites W1934344929 @default.
• W2112154893 cites W196336819 @default.
• W2112154893 cites W1966283310 @default.
• W2112154893 cites W1967354181 @default.
• W2112154893 cites W1979478767 @default.
• W2112154893 cites W1984621034 @default.
• W2112154893 cites W1988130512 @default.
• W2112154893 cites W1989502871 @default.
• W2112154893 cites W1989983802 @default.
• W2112154893 cites W1998079233 @default.
• W2112154893 cites W2006564041 @default.
• W2112154893 cites W2008701472 @default.
• W2112154893 cites W2009162031 @default.
• W2112154893 cites W2015578999 @default.
• W2112154893 cites W2020218579 @default.
• W2112154893 cites W2023463494 @default.
• W2112154893 cites W2028022561 @default.
• W2112154893 cites W2028722252 @default.
• W2112154893 cites W2031573639 @default.
• W2112154893 cites W2037113547 @default.
• W2112154893 cites W2038901822 @default.
• W2112154893 cites W2039824013 @default.
• W2112154893 cites W2048176236 @default.
• W2112154893 cites W2058442870 @default.
• W2112154893 cites W2072376288 @default.
• W2112154893 cites W2078255857 @default.
• W2112154893 cites W2081627112 @default.
• W2112154893 cites W2084245939 @default.
• W2112154893 cites W2096581318 @default.
• W2112154893 cites W2100222319 @default.
• W2112154893 cites W2101073547 @default.
• W2112154893 cites W2101430310 @default.
• W2112154893 cites W2107151425 @default.
• W2112154893 cites W2116034909 @default.
• W2112154893 cites W2116486649 @default.
• W2112154893 cites W2117137797 @default.
• W2112154893 cites W2117367522 @default.
• W2112154893 cites W2117829414 @default.
• W2112154893 cites W2124064310 @default.
• W2112154893 cites W2149842796 @default.
• W2112154893 cites W2150415541 @default.
• W2112154893 cites W2150644950 @default.
• W2112154893 cites W2152658642 @default.
• W2112154893 cites W2157369640 @default.
• W2112154893 cites W2157471512 @default.
• W2112154893 cites W2157977969 @default.
• W2112154893 cites W2161200392 @default.
• W2112154893 cites W2163125609 @default.
• W2112154893 cites W2165811661 @default.
• W2112154893 cites W2167575052 @default.
• W2112154893 cites W2170848108 @default.
• W2112154893 cites W2172232073 @default.
• W2112154893 cites W2175362133 @default.
• W2112154893 doi "https://doi.org/10.1111/trf.12348" @default.
• W2112154893 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4410835" @default.
• W2112154893 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23889533" @default.
• W2112154893 hasPublicationYear "2013" @default.
• W2112154893 type Work @default.
• W2112154893 sameAs 2112154893 @default.
• W2112154893 citedByCount "100" @default.
• W2112154893 countsByYear W21121548932014 @default.
• W2112154893 countsByYear W21121548932015 @default.
• W2112154893 countsByYear W21121548932016 @default.
• W2112154893 countsByYear W21121548932017 @default.
• W2112154893 countsByYear W21121548932018 @default.
• W2112154893 countsByYear W21121548932019 @default.
• W2112154893 countsByYear W21121548932020 @default.
• W2112154893 countsByYear W21121548932021 @default.
• W2112154893 countsByYear W21121548932022 @default.
• W2112154893 countsByYear W21121548932023 @default.
• W2112154893 crossrefType "journal-article" @default.
• W2112154893 hasAuthorship W2112154893A5003499192 @default.
• W2112154893 hasAuthorship W2112154893A5032872264 @default.
• W2112154893 hasAuthorship W2112154893A5038535078 @default.
• W2112154893 hasAuthorship W2112154893A5042878817 @default.
• W2112154893 hasAuthorship W2112154893A5043948649 @default.

• next