FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2112282209> ?p ?o ?g. }

• W2112282209 endingPage "10" @default.
• W2112282209 startingPage "1" @default.
• W2112282209 abstract "This study aims to investigate the anti-inflammatory responses and mechanisms of Siegesbeckia orientalis ethanol extract (SOE). In cell culture experiments, RAW264.7 cells were pretreated with SOE and stimulated with lipopolysaccharide (LPS) for inflammatory mediators assay. In animal experiments, mice were tube-fed with SOE for 1 week, and s.c. injected with λ -carrageenan or i.p. injected with LPS to simulate inflammation. The degree of paw edema was assessed, and cytokine profile in sera and mouse survival were recorded. Data showed that SOE significantly reduced NO, IL-6, and TNF-α production in LPS-stimulated RAW264.7 cells. In vivo studies demonstrated that mice supplemented with 32 mg SOE/kg BW/day significantly lowered sera IL-6 level and resulted a higher survival rate compared to the control group (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M1><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>0.019</mml:mn></mml:math>). Furthermore, SOE inhibited LPS-induced NF- κ B activation by blocking the degradation of I κ B-α. The SOE also reduced significantly the phosphorylation of ERK1/2, p38, and JNK in a dose-dependent manner. In summary, the in vitro and in vivo evidence indicate that SOE can attenuate acute inflammation by inhibiting inflammatory mediators via suppression of MAPKs- and NF- κ B-dependent pathways." @default.
• W2112282209 created "2016-06-24" @default.
• W2112282209 creator A5010509625 @default.
• W2112282209 creator A5026631102 @default.
• W2112282209 creator A5043944014 @default.
• W2112282209 creator A5078948133 @default.
• W2112282209 creator A5080747101 @default.
• W2112282209 creator A5084906244 @default.
• W2112282209 creator A5091525210 @default.
• W2112282209 date "2014-01-01" @default.
• W2112282209 modified "2023-10-18" @default.
• W2112282209 title "Anti-Inflammatory Effects of<i>Siegesbeckia orientalis</i>Ethanol Extract in<i>In Vitro</i>and<i>In Vivo</i>Models" @default.
• W2112282209 cites W1480232597 @default.
• W2112282209 cites W1499902555 @default.
• W2112282209 cites W1969237487 @default.
• W2112282209 cites W1975537939 @default.
• W2112282209 cites W1985049657 @default.
• W2112282209 cites W1990418324 @default.
• W2112282209 cites W1991819571 @default.
• W2112282209 cites W2000427727 @default.
• W2112282209 cites W2002831954 @default.
• W2112282209 cites W2011615366 @default.
• W2112282209 cites W2016992422 @default.
• W2112282209 cites W2025322791 @default.
• W2112282209 cites W2028600482 @default.
• W2112282209 cites W2044325823 @default.
• W2112282209 cites W2046428971 @default.
• W2112282209 cites W2052887838 @default.
• W2112282209 cites W2056512813 @default.
• W2112282209 cites W2063053022 @default.
• W2112282209 cites W2088243214 @default.
• W2112282209 cites W2096055070 @default.
• W2112282209 cites W2096667163 @default.
• W2112282209 cites W2098257287 @default.
• W2112282209 cites W2133439754 @default.
• W2112282209 cites W2140287009 @default.
• W2112282209 cites W2144610142 @default.
• W2112282209 cites W2163625494 @default.
• W2112282209 cites W4313335068 @default.
• W2112282209 doi "https://doi.org/10.1155/2014/329712" @default.
• W2112282209 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4160630" @default.
• W2112282209 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25328884" @default.
• W2112282209 hasPublicationYear "2014" @default.
• W2112282209 type Work @default.
• W2112282209 sameAs 2112282209 @default.
• W2112282209 citedByCount "23" @default.
• W2112282209 countsByYear W21122822092016 @default.
• W2112282209 countsByYear W21122822092017 @default.
• W2112282209 countsByYear W21122822092018 @default.
• W2112282209 countsByYear W21122822092019 @default.
• W2112282209 countsByYear W21122822092020 @default.
• W2112282209 countsByYear W21122822092021 @default.
• W2112282209 countsByYear W21122822092022 @default.
• W2112282209 countsByYear W21122822092023 @default.
• W2112282209 crossrefType "journal-article" @default.
• W2112282209 hasAuthorship W2112282209A5010509625 @default.
• W2112282209 hasAuthorship W2112282209A5026631102 @default.
• W2112282209 hasAuthorship W2112282209A5043944014 @default.
• W2112282209 hasAuthorship W2112282209A5078948133 @default.
• W2112282209 hasAuthorship W2112282209A5080747101 @default.
• W2112282209 hasAuthorship W2112282209A5084906244 @default.
• W2112282209 hasAuthorship W2112282209A5091525210 @default.
• W2112282209 hasBestOaLocation W21122822091 @default.
• W2112282209 hasConcept C11960822 @default.
• W2112282209 hasConcept C150903083 @default.
• W2112282209 hasConcept C17991360 @default.
• W2112282209 hasConcept C185592680 @default.
• W2112282209 hasConcept C202751555 @default.
• W2112282209 hasConcept C203014093 @default.
• W2112282209 hasConcept C207001950 @default.
• W2112282209 hasConcept C2776914184 @default.
• W2112282209 hasConcept C2777730290 @default.
• W2112282209 hasConcept C2778690821 @default.
• W2112282209 hasConcept C2778754761 @default.
• W2112282209 hasConcept C2780161600 @default.
• W2112282209 hasConcept C2781227287 @default.
• W2112282209 hasConcept C55493867 @default.
• W2112282209 hasConcept C71924100 @default.
• W2112282209 hasConcept C86803240 @default.
• W2112282209 hasConcept C98274493 @default.
• W2112282209 hasConceptScore W2112282209C11960822 @default.
• W2112282209 hasConceptScore W2112282209C150903083 @default.
• W2112282209 hasConceptScore W2112282209C17991360 @default.
• W2112282209 hasConceptScore W2112282209C185592680 @default.
• W2112282209 hasConceptScore W2112282209C202751555 @default.
• W2112282209 hasConceptScore W2112282209C203014093 @default.
• W2112282209 hasConceptScore W2112282209C207001950 @default.
• W2112282209 hasConceptScore W2112282209C2776914184 @default.
• W2112282209 hasConceptScore W2112282209C2777730290 @default.
• W2112282209 hasConceptScore W2112282209C2778690821 @default.
• W2112282209 hasConceptScore W2112282209C2778754761 @default.
• W2112282209 hasConceptScore W2112282209C2780161600 @default.
• W2112282209 hasConceptScore W2112282209C2781227287 @default.
• W2112282209 hasConceptScore W2112282209C55493867 @default.
• W2112282209 hasConceptScore W2112282209C71924100 @default.
• W2112282209 hasConceptScore W2112282209C86803240 @default.
• W2112282209 hasConceptScore W2112282209C98274493 @default.
• W2112282209 hasFunder F4320321040 @default.

• next