FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2112452073> ?p ?o ?g. }

• W2112452073 endingPage "3365" @default.
• W2112452073 startingPage "3359" @default.
• W2112452073 abstract "Cryptococcus neoformans capsule structure modifications after prolonged in vitro growth or in vivo passaging have been reported previously. However, nothing is known about the dynamics of these modifications or about their environmental specificities. In this study, capsule structure modifications after mouse passaging and prolonged in vitro culturing were analyzed by flow cytometry using the glucuronoxylomannan-specific monoclonal antibody E1. The capsule structures of strains recovered after 0, 1, 8, and 35 days were compared by using the level of E1-specific epitope expression and its cell-to-cell heterogeneity within a given cell population. In vitro, according to these parameters, the diversity of the strains was higher on day 35 than it was initially, suggesting the absence of selection during in vitro culturing. In contrast, the diversity of the strains recovered from the brain tended to decrease over time, suggesting that selection of more adapted strains had occurred. The strains recovered on day 35 from the spleen and the lungs had different phenotypes than the strains isolated from the brain of the same mouse on the same day, thus strongly suggesting that there is organ specificity for C. neoformans strain selection. Fingerprinting of the strains recovered in vitro and in vivo over time confirmed that genotypes evolved very differently in vitro and in vivo, depending on the environment. Overall, our results suggest that organ-specific selection can occur during cryptococcosis." @default.
• W2112452073 created "2016-06-24" @default.
• W2112452073 creator A5059831856 @default.
• W2112452073 creator A5069120270 @default.
• W2112452073 creator A5076696329 @default.
• W2112452073 date "2004-06-01" @default.
• W2112452073 modified "2023-10-16" @default.
• W2112452073 title "<i>Cryptococcus neoformans</i> Capsule Structure Evolution In Vitro and during Murine Infection" @default.
• W2112452073 cites W1539606662 @default.
• W2112452073 cites W1552395051 @default.
• W2112452073 cites W1594912029 @default.
• W2112452073 cites W1703812573 @default.
• W2112452073 cites W1824251371 @default.
• W2112452073 cites W1842799431 @default.
• W2112452073 cites W1955295475 @default.
• W2112452073 cites W1982611069 @default.
• W2112452073 cites W2000146338 @default.
• W2112452073 cites W2004641081 @default.
• W2112452073 cites W2055599095 @default.
• W2112452073 cites W2066050762 @default.
• W2112452073 cites W2078907613 @default.
• W2112452073 cites W2095975495 @default.
• W2112452073 cites W2103669668 @default.
• W2112452073 cites W2115408128 @default.
• W2112452073 cites W2120739562 @default.
• W2112452073 cites W2141532974 @default.
• W2112452073 cites W2145682730 @default.
• W2112452073 cites W2151840748 @default.
• W2112452073 cites W2152741877 @default.
• W2112452073 cites W2158262979 @default.
• W2112452073 cites W2159527831 @default.
• W2112452073 cites W2159733879 @default.
• W2112452073 cites W2162172362 @default.
• W2112452073 cites W2162456739 @default.
• W2112452073 cites W2163652419 @default.
• W2112452073 cites W2163791401 @default.
• W2112452073 cites W2163904534 @default.
• W2112452073 cites W2167614997 @default.
• W2112452073 cites W2167618817 @default.
• W2112452073 cites W2168471667 @default.
• W2112452073 cites W2172090846 @default.
• W2112452073 doi "https://doi.org/10.1128/iai.72.6.3359-3365.2004" @default.
• W2112452073 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/415706" @default.
• W2112452073 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15155641" @default.
• W2112452073 hasPublicationYear "2004" @default.
• W2112452073 type Work @default.
• W2112452073 sameAs 2112452073 @default.
• W2112452073 citedByCount "74" @default.
• W2112452073 countsByYear W21124520732012 @default.
• W2112452073 countsByYear W21124520732013 @default.
• W2112452073 countsByYear W21124520732014 @default.
• W2112452073 countsByYear W21124520732015 @default.
• W2112452073 countsByYear W21124520732016 @default.
• W2112452073 countsByYear W21124520732017 @default.
• W2112452073 countsByYear W21124520732018 @default.
• W2112452073 countsByYear W21124520732019 @default.
• W2112452073 countsByYear W21124520732020 @default.
• W2112452073 countsByYear W21124520732021 @default.
• W2112452073 countsByYear W21124520732022 @default.
• W2112452073 countsByYear W21124520732023 @default.
• W2112452073 crossrefType "journal-article" @default.
• W2112452073 hasAuthorship W2112452073A5059831856 @default.
• W2112452073 hasAuthorship W2112452073A5069120270 @default.
• W2112452073 hasAuthorship W2112452073A5076696329 @default.
• W2112452073 hasBestOaLocation W21124520731 @default.
• W2112452073 hasConcept C144024400 @default.
• W2112452073 hasConcept C149923435 @default.
• W2112452073 hasConcept C159654299 @default.
• W2112452073 hasConcept C195616568 @default.
• W2112452073 hasConcept C202751555 @default.
• W2112452073 hasConcept C203014093 @default.
• W2112452073 hasConcept C207001950 @default.
• W2112452073 hasConcept C2777893358 @default.
• W2112452073 hasConcept C2779413141 @default.
• W2112452073 hasConcept C2780931953 @default.
• W2112452073 hasConcept C2908647359 @default.
• W2112452073 hasConcept C542903549 @default.
• W2112452073 hasConcept C54355233 @default.
• W2112452073 hasConcept C86803240 @default.
• W2112452073 hasConcept C89423630 @default.
• W2112452073 hasConceptScore W2112452073C144024400 @default.
• W2112452073 hasConceptScore W2112452073C149923435 @default.
• W2112452073 hasConceptScore W2112452073C159654299 @default.
• W2112452073 hasConceptScore W2112452073C195616568 @default.
• W2112452073 hasConceptScore W2112452073C202751555 @default.
• W2112452073 hasConceptScore W2112452073C203014093 @default.
• W2112452073 hasConceptScore W2112452073C207001950 @default.
• W2112452073 hasConceptScore W2112452073C2777893358 @default.
• W2112452073 hasConceptScore W2112452073C2779413141 @default.
• W2112452073 hasConceptScore W2112452073C2780931953 @default.
• W2112452073 hasConceptScore W2112452073C2908647359 @default.
• W2112452073 hasConceptScore W2112452073C542903549 @default.
• W2112452073 hasConceptScore W2112452073C54355233 @default.
• W2112452073 hasConceptScore W2112452073C86803240 @default.
• W2112452073 hasConceptScore W2112452073C89423630 @default.
• W2112452073 hasIssue "6" @default.
• W2112452073 hasLocation W21124520731 @default.
• W2112452073 hasLocation W21124520732 @default.

• next