FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2112597372> ?p ?o ?g. }

• W2112597372 endingPage "35" @default.
• W2112597372 startingPage "32" @default.
• W2112597372 abstract "Obesity, measured as body mass index (BMI), has been identified as a possible risk factor for several solid tumors as well as for chronic myeloid leukemia (CML). To date, no correlations have been reported in this latter disease between BMI at baseline and response to targeted therapies. We refer here on the impact of BMI on clinical response in 339 chronic phase (CP) CML patients treated with imatinib and 35 CP-CML patients treated frontline with nilotinib. If compared to patients with low BMI (<18.5-25), patients with increased BMI (>25-40) at diagnosis who received imatinib showed a significantly longer median time to achieve complete cytogenetic response (6.8 months vs 3.3 months, p=0.001), a reduced rate of major molecular response (77% vs 58%, p=0.01) which was also achieved in a longer median time (29 months compared to 14 months, p=0.01). Conversely, no differences were revealed with respect to BMI in patients treated frontline with nilotinib and also patients with increased BMI obtained rapidly CCyR and MMR with an incidence similar to that of underweight/normal weight patients. These results suggest that CML patients with increased weight at baseline should be followed and carefully monitored if treated with standard dose imatinib frontline for a possible early switch." @default.
• W2112597372 created "2016-06-24" @default.
• W2112597372 creator A5006023644 @default.
• W2112597372 creator A5006030842 @default.
• W2112597372 creator A5008958861 @default.
• W2112597372 creator A5014873864 @default.
• W2112597372 creator A5034677841 @default.
• W2112597372 creator A5035666231 @default.
• W2112597372 creator A5085402984 @default.
• W2112597372 creator A5089760320 @default.
• W2112597372 date "2013-06-01" @default.
• W2112597372 modified "2023-09-23" @default.
• W2112597372 title "Delayed cytogenetic and major molecular responses associated to increased BMI at baseline in chronic myeloid leukemia patients treated with imatinib" @default.
• W2112597372 cites W1970203534 @default.
• W2112597372 cites W1994361908 @default.
• W2112597372 cites W2005106433 @default.
• W2112597372 cites W2009746825 @default.
• W2112597372 cites W2014171165 @default.
• W2112597372 cites W2020937563 @default.
• W2112597372 cites W2028669471 @default.
• W2112597372 cites W2029759511 @default.
• W2112597372 cites W2041028326 @default.
• W2112597372 cites W2049605227 @default.
• W2112597372 cites W2096112294 @default.
• W2112597372 cites W2108460105 @default.
• W2112597372 cites W2121845219 @default.
• W2112597372 cites W2126589441 @default.
• W2112597372 cites W2141662760 @default.
• W2112597372 cites W2164282978 @default.
• W2112597372 cites W2166312294 @default.
• W2112597372 cites W2166426001 @default.
• W2112597372 cites W2166654361 @default.
• W2112597372 cites W2168747539 @default.
• W2112597372 cites W2560926689 @default.
• W2112597372 cites W2564723484 @default.
• W2112597372 cites W2587781815 @default.
• W2112597372 doi "https://doi.org/10.1016/j.canlet.2012.12.018" @default.
• W2112597372 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23291359" @default.
• W2112597372 hasPublicationYear "2013" @default.
• W2112597372 type Work @default.
• W2112597372 sameAs 2112597372 @default.
• W2112597372 citedByCount "17" @default.
• W2112597372 countsByYear W21125973722013 @default.
• W2112597372 countsByYear W21125973722015 @default.
• W2112597372 countsByYear W21125973722016 @default.
• W2112597372 countsByYear W21125973722017 @default.
• W2112597372 countsByYear W21125973722018 @default.
• W2112597372 countsByYear W21125973722021 @default.
• W2112597372 countsByYear W21125973722022 @default.
• W2112597372 countsByYear W21125973722023 @default.
• W2112597372 crossrefType "journal-article" @default.
• W2112597372 hasAuthorship W2112597372A5006023644 @default.
• W2112597372 hasAuthorship W2112597372A5006030842 @default.
• W2112597372 hasAuthorship W2112597372A5008958861 @default.
• W2112597372 hasAuthorship W2112597372A5014873864 @default.
• W2112597372 hasAuthorship W2112597372A5034677841 @default.
• W2112597372 hasAuthorship W2112597372A5035666231 @default.
• W2112597372 hasAuthorship W2112597372A5085402984 @default.
• W2112597372 hasAuthorship W2112597372A5089760320 @default.
• W2112597372 hasConcept C126322002 @default.
• W2112597372 hasConcept C141071460 @default.
• W2112597372 hasConcept C143998085 @default.
• W2112597372 hasConcept C2777413986 @default.
• W2112597372 hasConcept C2777583451 @default.
• W2112597372 hasConcept C2778729363 @default.
• W2112597372 hasConcept C2780221984 @default.
• W2112597372 hasConcept C2780586474 @default.
• W2112597372 hasConcept C2781121325 @default.
• W2112597372 hasConcept C3019892230 @default.
• W2112597372 hasConcept C71924100 @default.
• W2112597372 hasConcept C90924648 @default.
• W2112597372 hasConceptScore W2112597372C126322002 @default.
• W2112597372 hasConceptScore W2112597372C141071460 @default.
• W2112597372 hasConceptScore W2112597372C143998085 @default.
• W2112597372 hasConceptScore W2112597372C2777413986 @default.
• W2112597372 hasConceptScore W2112597372C2777583451 @default.
• W2112597372 hasConceptScore W2112597372C2778729363 @default.
• W2112597372 hasConceptScore W2112597372C2780221984 @default.
• W2112597372 hasConceptScore W2112597372C2780586474 @default.
• W2112597372 hasConceptScore W2112597372C2781121325 @default.
• W2112597372 hasConceptScore W2112597372C3019892230 @default.
• W2112597372 hasConceptScore W2112597372C71924100 @default.
• W2112597372 hasConceptScore W2112597372C90924648 @default.
• W2112597372 hasIssue "1" @default.
• W2112597372 hasLocation W21125973721 @default.
• W2112597372 hasLocation W21125973722 @default.
• W2112597372 hasOpenAccess W2112597372 @default.
• W2112597372 hasPrimaryLocation W21125973721 @default.
• W2112597372 hasRelatedWork W1510497893 @default.
• W2112597372 hasRelatedWork W2001289393 @default.
• W2112597372 hasRelatedWork W2051726599 @default.
• W2112597372 hasRelatedWork W2073935113 @default.
• W2112597372 hasRelatedWork W2112597372 @default.
• W2112597372 hasRelatedWork W2120868842 @default.
• W2112597372 hasRelatedWork W2134832378 @default.
• W2112597372 hasRelatedWork W4230849756 @default.
• W2112597372 hasRelatedWork W4245675997 @default.
• W2112597372 hasRelatedWork W54919303 @default.

• next