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- W2112658045 abstract "Chronic obstructive pulmonary disease (COPD) is characterized by airflow limitation of peripheral airways that is not fully reversible. COPD is associated with airway remodeling, which thickens the airway walls and narrows the air- way as a result. Exposure to cigarette smoke is the major risk factor for this condition. Pathogens including viruses and bacteria may induce COPD exacerbations. Now there is more evidence to suggest a significant relationship between air- way epithelial cells and the pathogenesis of COPD. Airway epithelial cells make up an efficient barrier against pathogens and aggressive molecules. However, after exposure to cigarette smoke and pathogens, epithelial cells are stimulated to re- lease a variety of pro-inflammatory mediators, including chemokines, cytokines, and growth factors through signaling pathways. These mediators recruit or stimulate other types of cells to induce an increased inflammatory response, produc- tion of mucus, and finally result in airway remodeling. After epithelium injury, epithelial cells participate in the process of repair and regeneration to maintain the epithelial integrity. A better understanding of the role of airway epithelial cells in COPD may be valuable to provide a basis for new therapeutic strategies." @default.
- W2112658045 created "2016-06-24" @default.
- W2112658045 creator A5000830943 @default.
- W2112658045 creator A5023185995 @default.
- W2112658045 creator A5052830364 @default.
- W2112658045 date "2009-09-11" @default.
- W2112658045 modified "2023-09-26" @default.
- W2112658045 title "Role of Airway Epithelial Cells in Development of Chronic Obstructive Pulmonary Disease" @default.
- W2112658045 cites W1517798087 @default.
- W2112658045 cites W1589536132 @default.
- W2112658045 cites W1598802044 @default.
- W2112658045 cites W1918510262 @default.
- W2112658045 cites W1974793843 @default.
- W2112658045 cites W1977273234 @default.
- W2112658045 cites W1978078087 @default.
- W2112658045 cites W1979628343 @default.
- W2112658045 cites W1980191732 @default.
- W2112658045 cites W1981681632 @default.
- W2112658045 cites W1991648511 @default.
- W2112658045 cites W2002946463 @default.
- W2112658045 cites W2009851978 @default.
- W2112658045 cites W2010846919 @default.
- W2112658045 cites W2012416135 @default.
- W2112658045 cites W2013483737 @default.
- W2112658045 cites W2019737644 @default.
- W2112658045 cites W2021453566 @default.
- W2112658045 cites W2021583977 @default.
- W2112658045 cites W2022169398 @default.
- W2112658045 cites W2022670940 @default.
- W2112658045 cites W2028433125 @default.
- W2112658045 cites W2030563465 @default.
- W2112658045 cites W2031735271 @default.
- W2112658045 cites W2033815220 @default.
- W2112658045 cites W2038132658 @default.
- W2112658045 cites W2040884453 @default.
- W2112658045 cites W2045616259 @default.
- W2112658045 cites W2050716480 @default.
- W2112658045 cites W2057299941 @default.
- W2112658045 cites W2059879972 @default.
- W2112658045 cites W2071093148 @default.
- W2112658045 cites W2072099958 @default.
- W2112658045 cites W2075729495 @default.
- W2112658045 cites W2075782763 @default.
- W2112658045 cites W2079427948 @default.
- W2112658045 cites W2080011794 @default.
- W2112658045 cites W2084684444 @default.
- W2112658045 cites W2089417149 @default.
- W2112658045 cites W2095800013 @default.
- W2112658045 cites W2098582660 @default.
- W2112658045 cites W2107390586 @default.
- W2112658045 cites W2108020449 @default.
- W2112658045 cites W2110889216 @default.
- W2112658045 cites W2111025555 @default.
- W2112658045 cites W2112692443 @default.
- W2112658045 cites W2115268884 @default.
- W2112658045 cites W2115693059 @default.
- W2112658045 cites W2116522708 @default.
- W2112658045 cites W2117560139 @default.
- W2112658045 cites W2118289954 @default.
- W2112658045 cites W2118749829 @default.
- W2112658045 cites W2118755647 @default.
- W2112658045 cites W2125709882 @default.
- W2112658045 cites W2126029792 @default.
- W2112658045 cites W2127951128 @default.
- W2112658045 cites W2128052381 @default.
- W2112658045 cites W2128343842 @default.
- W2112658045 cites W2128794104 @default.
- W2112658045 cites W2140662865 @default.
- W2112658045 cites W2142555112 @default.
- W2112658045 cites W2143155947 @default.
- W2112658045 cites W2144477621 @default.
- W2112658045 cites W2145621175 @default.
- W2112658045 cites W2145905558 @default.
- W2112658045 cites W2145959603 @default.
- W2112658045 cites W2146032890 @default.
- W2112658045 cites W2148578992 @default.
- W2112658045 cites W2149253818 @default.
- W2112658045 cites W2150311411 @default.
- W2112658045 cites W2153924942 @default.
- W2112658045 cites W2154646748 @default.
- W2112658045 cites W2154846778 @default.
- W2112658045 cites W2156225283 @default.
- W2112658045 cites W2158026075 @default.
- W2112658045 cites W2162186194 @default.
- W2112658045 cites W2162871226 @default.
- W2112658045 cites W2163984817 @default.
- W2112658045 cites W2165757151 @default.
- W2112658045 cites W2168504646 @default.
- W2112658045 cites W2259200932 @default.
- W2112658045 cites W2314522446 @default.
- W2112658045 cites W2515280055 @default.
- W2112658045 doi "https://doi.org/10.2174/1875044300902010044" @default.
- W2112658045 hasPublicationYear "2009" @default.
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