FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2112665890> ?p ?o ?g. }

• W2112665890 endingPage "908" @default.
• W2112665890 startingPage "902" @default.
• W2112665890 abstract "In cirrhotic patients under pharmacologic treatment for portal hypertension, a reduction in hepatic venous pressure gradient (HVPG) of >or=20% of baseline or to <or=12 mm Hg markedly reduces the risk of variceal rebleeding. This study was aimed at evaluating whether these hemodynamic targets also prevent other complications of portal hypertension and improve long-term survival. One hundred five cirrhotic patients included in prospective trials for the prevention of variceal rebleeding were studied. Seventy-three of the patients had 2 separate HVPG measurements, at baseline and under pharmacologic therapy with propranolol +/- isosorbide mononitrate. Patients were followed for up to 8 years. Survival and risk of developing portal hypertension-related complications were compared between responders and nonresponders. Twenty-eight patients showed a reduction of HVPG >or=20% of baseline or to <or=12 mm Hg (responders), and 45 patients were nonresponders. Nonresponders had a significantly greater risk of developing variceal rebleeding (P =.013), ascites (P =.025), spontaneous bacterial peritonitis (P =.003), hepatorenal syndrome (P =.026), and hepatic encephalopathy (P =.024) than responders. Eight-year cumulative probability of survival was significantly lower in nonresponders than in responders (52% vs. 95%, respectively, P =.003). At multivariate analysis, being a nonresponder was independently associated with the risk of developing rebleeding, ascites, spontaneous bacterial peritonitis, and lower survival. In conclusion, in cirrhotic patients receiving pharmacologic treatment for prevention of variceal rebleeding, a decrease in HVPG >or=20% or to <or=12 mm Hg is associated with a marked reduction in the long-term risk of developing complications of portal hypertension and with improved survival." @default.
• W2112665890 created "2016-06-24" @default.
• W2112665890 creator A5012387403 @default.
• W2112665890 creator A5022846808 @default.
• W2112665890 creator A5027268186 @default.
• W2112665890 creator A5068341379 @default.
• W2112665890 creator A5072599627 @default.
• W2112665890 creator A5085194045 @default.
• W2112665890 date "2003-04-01" @default.
• W2112665890 modified "2023-10-09" @default.
• W2112665890 title "Hemodynamic response to pharmacological treatment of portal hypertension and long-term prognosis of cirrhosis" @default.
• W2112665890 cites W1490907837 @default.
• W2112665890 cites W1963673927 @default.
• W2112665890 cites W1970072092 @default.
• W2112665890 cites W1973164007 @default.
• W2112665890 cites W1976142493 @default.
• W2112665890 cites W1980938177 @default.
• W2112665890 cites W1988005853 @default.
• W2112665890 cites W1994698457 @default.
• W2112665890 cites W1997131223 @default.
• W2112665890 cites W2003458286 @default.
• W2112665890 cites W2007677328 @default.
• W2112665890 cites W2010918676 @default.
• W2112665890 cites W2024642291 @default.
• W2112665890 cites W2025606754 @default.
• W2112665890 cites W2042414030 @default.
• W2112665890 cites W2043121221 @default.
• W2112665890 cites W2044402850 @default.
• W2112665890 cites W2044457468 @default.
• W2112665890 cites W2052113409 @default.
• W2112665890 cites W2067864626 @default.
• W2112665890 cites W2069243984 @default.
• W2112665890 cites W2089482666 @default.
• W2112665890 cites W2091806278 @default.
• W2112665890 cites W2119790378 @default.
• W2112665890 cites W2120179295 @default.
• W2112665890 cites W2131206408 @default.
• W2112665890 cites W2140962120 @default.
• W2112665890 cites W2141632000 @default.
• W2112665890 cites W2153951446 @default.
• W2112665890 cites W2171943778 @default.
• W2112665890 doi "https://doi.org/10.1053/jhep.2003.50133" @default.
• W2112665890 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12668985" @default.
• W2112665890 hasPublicationYear "2003" @default.
• W2112665890 type Work @default.
• W2112665890 sameAs 2112665890 @default.
• W2112665890 citedByCount "473" @default.
• W2112665890 countsByYear W21126658902012 @default.
• W2112665890 countsByYear W21126658902013 @default.
• W2112665890 countsByYear W21126658902014 @default.
• W2112665890 countsByYear W21126658902015 @default.
• W2112665890 countsByYear W21126658902016 @default.
• W2112665890 countsByYear W21126658902017 @default.
• W2112665890 countsByYear W21126658902018 @default.
• W2112665890 countsByYear W21126658902019 @default.
• W2112665890 countsByYear W21126658902020 @default.
• W2112665890 countsByYear W21126658902021 @default.
• W2112665890 countsByYear W21126658902022 @default.
• W2112665890 countsByYear W21126658902023 @default.
• W2112665890 crossrefType "journal-article" @default.
• W2112665890 hasAuthorship W2112665890A5012387403 @default.
• W2112665890 hasAuthorship W2112665890A5022846808 @default.
• W2112665890 hasAuthorship W2112665890A5027268186 @default.
• W2112665890 hasAuthorship W2112665890A5068341379 @default.
• W2112665890 hasAuthorship W2112665890A5072599627 @default.
• W2112665890 hasAuthorship W2112665890A5085194045 @default.
• W2112665890 hasConcept C126322002 @default.
• W2112665890 hasConcept C178853913 @default.
• W2112665890 hasConcept C2776988256 @default.
• W2112665890 hasConcept C2777214474 @default.
• W2112665890 hasConcept C2777364826 @default.
• W2112665890 hasConcept C2778492647 @default.
• W2112665890 hasConcept C2778808290 @default.
• W2112665890 hasConcept C2780325230 @default.
• W2112665890 hasConcept C2780496750 @default.
• W2112665890 hasConcept C56900294 @default.
• W2112665890 hasConcept C71924100 @default.
• W2112665890 hasConcept C90924648 @default.
• W2112665890 hasConceptScore W2112665890C126322002 @default.
• W2112665890 hasConceptScore W2112665890C178853913 @default.
• W2112665890 hasConceptScore W2112665890C2776988256 @default.
• W2112665890 hasConceptScore W2112665890C2777214474 @default.
• W2112665890 hasConceptScore W2112665890C2777364826 @default.
• W2112665890 hasConceptScore W2112665890C2778492647 @default.
• W2112665890 hasConceptScore W2112665890C2778808290 @default.
• W2112665890 hasConceptScore W2112665890C2780325230 @default.
• W2112665890 hasConceptScore W2112665890C2780496750 @default.
• W2112665890 hasConceptScore W2112665890C56900294 @default.
• W2112665890 hasConceptScore W2112665890C71924100 @default.
• W2112665890 hasConceptScore W2112665890C90924648 @default.
• W2112665890 hasIssue "4" @default.
• W2112665890 hasLocation W21126658901 @default.
• W2112665890 hasLocation W21126658902 @default.
• W2112665890 hasOpenAccess W2112665890 @default.
• W2112665890 hasPrimaryLocation W21126658901 @default.
• W2112665890 hasRelatedWork W156267672 @default.
• W2112665890 hasRelatedWork W157618018 @default.
• W2112665890 hasRelatedWork W2112665890 @default.

• next