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• W2112799238 abstract "Porcine intestinal mucosal heparin induced aggregation of platelets in citrated platelet-rich plasma and enhanced platelet aggregation and serotonin secretion induced by other agents. This action of heparin was blocked by substances that elevate platelet cyclic AMP and by EDTA but not by inhibitors of platelet cyclooxygenase. The effect was not inhibited by apyrase or by N-amylthio-5′-AMP and therefore did not require the action of ADP, nor was there activation of platelet phospholipase. Platelet aggregation by heparin required a plasma cofactor different from the cofactor required for ristocetin." @default.
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• W2112799238 date "1980-01-01" @default.
• W2112799238 modified "2023-10-18" @default.
• W2112799238 title "Effect of Heparin and Heparin Fractions on Platelet Aggregation" @default.
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• W2112799238 doi "https://doi.org/10.1172/jci109661" @default.
• W2112799238 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/371340" @default.
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