FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2112865723> ?p ?o ?g. }

• W2112865723 endingPage "e0118676" @default.
• W2112865723 startingPage "e0118676" @default.
• W2112865723 abstract "Background Chronic kidney disease (CKD) diagnosis relies on glomerular filtration rate (eGFR) estimation, traditionally using the creatinine-based Modification of Diet in Renal Disease (MDRD) equation. The Chronic Kidney Disease Epidemiology Collaboration (CKDEPI) equation performs better in estimating eGFR and predicting mortality and CKD progression risk. Cystatin C is an alternative glomerular filtration marker less influenced by muscle mass. CKD risk stratification is improved by combining creatinine eGFR with cystatin C and urinary albumin to creatinine ratio (uACR). We aimed to identify the impact of introducing CKDEPI and cystatin C on the estimated prevalence and risk stratification of CKD in England and to describe prevalence and associations of cystatin C. Methods and Findings Cross sectional study of 5799 people in the nationally representative 2009 and 2010 Health Surveys for England. Primary outcome measures: prevalence of MDRD, CKDEPI and cystatin C-defined eGFR<60ml/min/1.73m2; prevalence of CKD biomarker combinations (creatinine, cystatin C, uACR). Using CKDEPI instead of MDRD reduced the prevalence of eGFR<60ml/min/1.73m2 from 6.0% (95% CI 5.4–6.6%) to 5.2% (4.7–5.8%) equivalent to around 340,000 fewer individuals in England. Those reclassified as not having CKD evidenced a lower risk profile. Prevalence of cystatin C eGFR<60ml/min/1.73m2 was 7.7% and independently associated with age, lack of qualifications, being an ex-smoker, BMI, hypertension, and albuminuria. Measuring cystatin C in the 3.9% people with CKDEPI-defined eGFR<60ml/min/1.73m2 without albuminuria (CKD Category G3a A1) reclassified about a third into a lower risk group with one of three biomarkers and two thirds into a group with two of three. Measuring cystatin C in the 6.7% people with CKDEPI eGFR >60ml/min/1.73m2 with albuminuria (CKD Category G1-2) reclassified almost a tenth into a higher risk group. Limitations Cross sectional study, single eGFR measure, no measured (‘true’) GFR. Conclusions Introducing the CKDEPI equation and targeted cystatin C measurement reduces estimated CKD prevalence and improves risk stratification." @default.
• W2112865723 created "2016-06-24" @default.
• W2112865723 creator A5005312226 @default.
• W2112865723 creator A5005373304 @default.
• W2112865723 creator A5016092863 @default.
• W2112865723 creator A5035403844 @default.
• W2112865723 creator A5050071734 @default.
• W2112865723 creator A5055789818 @default.
• W2112865723 creator A5091132477 @default.
• W2112865723 creator A5091004834 @default.
• W2112865723 date "2015-02-20" @default.
• W2112865723 modified "2023-09-26" @default.
• W2112865723 title "Exploration of Chronic Kidney Disease Prevalence Estimates Using New Measures of Kidney Function in the Health Survey for England" @default.
• W2112865723 cites W1570583414 @default.
• W2112865723 cites W2003056396 @default.
• W2112865723 cites W2010710496 @default.
• W2112865723 cites W2012817319 @default.
• W2112865723 cites W2031214846 @default.
• W2112865723 cites W2046655678 @default.
• W2112865723 cites W2047008219 @default.
• W2112865723 cites W2049382000 @default.
• W2112865723 cites W2049837938 @default.
• W2112865723 cites W2063007022 @default.
• W2112865723 cites W2071554031 @default.
• W2112865723 cites W2073742622 @default.
• W2112865723 cites W2077093911 @default.
• W2112865723 cites W2081231656 @default.
• W2112865723 cites W2098204192 @default.
• W2112865723 cites W2099628040 @default.
• W2112865723 cites W2100510417 @default.
• W2112865723 cites W2107030820 @default.
• W2112865723 cites W2108558582 @default.
• W2112865723 cites W2109355833 @default.
• W2112865723 cites W2114019720 @default.
• W2112865723 cites W2114142344 @default.
• W2112865723 cites W2118625269 @default.
• W2112865723 cites W2118625608 @default.
• W2112865723 cites W2123221059 @default.
• W2112865723 cites W2123775770 @default.
• W2112865723 cites W2126426840 @default.
• W2112865723 cites W2136066105 @default.
• W2112865723 cites W2136377175 @default.
• W2112865723 cites W2137354420 @default.
• W2112865723 cites W2155965977 @default.
• W2112865723 cites W2158148811 @default.
• W2112865723 cites W2329949330 @default.
• W2112865723 cites W2475261460 @default.
• W2112865723 cites W2582602949 @default.
• W2112865723 cites W2607031541 @default.
• W2112865723 doi "https://doi.org/10.1371/journal.pone.0118676" @default.
• W2112865723 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4336286" @default.
• W2112865723 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25700182" @default.
• W2112865723 hasPublicationYear "2015" @default.
• W2112865723 type Work @default.
• W2112865723 sameAs 2112865723 @default.
• W2112865723 citedByCount "25" @default.
• W2112865723 countsByYear W21128657232015 @default.
• W2112865723 countsByYear W21128657232016 @default.
• W2112865723 countsByYear W21128657232017 @default.
• W2112865723 countsByYear W21128657232018 @default.
• W2112865723 countsByYear W21128657232019 @default.
• W2112865723 countsByYear W21128657232020 @default.
• W2112865723 countsByYear W21128657232021 @default.
• W2112865723 countsByYear W21128657232022 @default.
• W2112865723 crossrefType "journal-article" @default.
• W2112865723 hasAuthorship W2112865723A5005312226 @default.
• W2112865723 hasAuthorship W2112865723A5005373304 @default.
• W2112865723 hasAuthorship W2112865723A5016092863 @default.
• W2112865723 hasAuthorship W2112865723A5035403844 @default.
• W2112865723 hasAuthorship W2112865723A5050071734 @default.
• W2112865723 hasAuthorship W2112865723A5055789818 @default.
• W2112865723 hasAuthorship W2112865723A5091004834 @default.
• W2112865723 hasAuthorship W2112865723A5091132477 @default.
• W2112865723 hasBestOaLocation W21128657231 @default.
• W2112865723 hasConcept C107130276 @default.
• W2112865723 hasConcept C126322002 @default.
• W2112865723 hasConcept C126894567 @default.
• W2112865723 hasConcept C134018914 @default.
• W2112865723 hasConcept C159641895 @default.
• W2112865723 hasConcept C2776174234 @default.
• W2112865723 hasConcept C2778653478 @default.
• W2112865723 hasConcept C2779548226 @default.
• W2112865723 hasConcept C2780306776 @default.
• W2112865723 hasConcept C2780412452 @default.
• W2112865723 hasConcept C71924100 @default.
• W2112865723 hasConceptScore W2112865723C107130276 @default.
• W2112865723 hasConceptScore W2112865723C126322002 @default.
• W2112865723 hasConceptScore W2112865723C126894567 @default.
• W2112865723 hasConceptScore W2112865723C134018914 @default.
• W2112865723 hasConceptScore W2112865723C159641895 @default.
• W2112865723 hasConceptScore W2112865723C2776174234 @default.
• W2112865723 hasConceptScore W2112865723C2778653478 @default.
• W2112865723 hasConceptScore W2112865723C2779548226 @default.
• W2112865723 hasConceptScore W2112865723C2780306776 @default.
• W2112865723 hasConceptScore W2112865723C2780412452 @default.
• W2112865723 hasConceptScore W2112865723C71924100 @default.
• W2112865723 hasIssue "2" @default.
• W2112865723 hasLocation W21128657231 @default.

• next