FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2112907971> ?p ?o ?g. }

• W2112907971 endingPage "18" @default.
• W2112907971 startingPage "1" @default.
• W2112907971 abstract "The APOBEC family of proteins comprises deaminase enzymes that edit DNA and/or RNA sequences. The APOBEC3 subgroup plays an important role on the innate immune system, acting on host defense against exogenous viruses and endogenous retroelements. The role of APOBEC3 proteins in the inhibition of viral infection was firstly described for HIV-1. However, in the past few years many studies have also shown evidence of APOBEC3 action on other viruses associated with human diseases, including HTLV, HCV, HBV, HPV, HSV-1, and EBV. APOBEC3 inhibits these viruses through a series of editing-dependent and independent mechanisms. Many viruses have evolved mechanisms to counteract APOBEC effects, and strategies that enhance APOBEC3 activity constitute a new approach for antiviral drug development. On the other hand, novel evidence that editing by APOBEC3 constitutes a source for viral genetic diversification and evolution has emerged. Furthermore, a possible role in cancer development has been shown for these host enzymes. Therefore, understanding the role of deaminases on the immune response against infectious agents, as well as their role in human disease, has become pivotal. This review summarizes the state-of-the-art knowledge of the impact of APOBEC enzymes on human viruses of distinct families and harboring disparate replication strategies." @default.
• W2112907971 created "2016-06-24" @default.
• W2112907971 creator A5000173153 @default.
• W2112907971 creator A5010403234 @default.
• W2112907971 date "2013-01-01" @default.
• W2112907971 modified "2023-10-16" @default.
• W2112907971 title "The Role of Cytidine Deaminases on Innate Immune Responses against Human Viral Infections" @default.
• W2112907971 cites W1503953082 @default.
• W2112907971 cites W1586205537 @default.
• W2112907971 cites W1930479567 @default.
• W2112907971 cites W1950704965 @default.
• W2112907971 cites W1966909891 @default.
• W2112907971 cites W1967005118 @default.
• W2112907971 cites W1967224500 @default.
• W2112907971 cites W1973464920 @default.
• W2112907971 cites W1973598278 @default.
• W2112907971 cites W1973732415 @default.
• W2112907971 cites W1973867356 @default.
• W2112907971 cites W1975250898 @default.
• W2112907971 cites W1975784563 @default.
• W2112907971 cites W1976965112 @default.
• W2112907971 cites W1977239712 @default.
• W2112907971 cites W1977998658 @default.
• W2112907971 cites W1978325079 @default.
• W2112907971 cites W1978624231 @default.
• W2112907971 cites W1978896670 @default.
• W2112907971 cites W1978920270 @default.
• W2112907971 cites W1980834036 @default.
• W2112907971 cites W1984236815 @default.
• W2112907971 cites W1985912950 @default.
• W2112907971 cites W1987064224 @default.
• W2112907971 cites W1987468364 @default.
• W2112907971 cites W1987787764 @default.
• W2112907971 cites W1988960099 @default.
• W2112907971 cites W1990248095 @default.
• W2112907971 cites W1990993204 @default.
• W2112907971 cites W1991069890 @default.
• W2112907971 cites W1992325700 @default.
• W2112907971 cites W1992648952 @default.
• W2112907971 cites W1992984336 @default.
• W2112907971 cites W1994780482 @default.
• W2112907971 cites W1995598331 @default.
• W2112907971 cites W1995911285 @default.
• W2112907971 cites W1996145257 @default.
• W2112907971 cites W1996737758 @default.
• W2112907971 cites W1996964330 @default.
• W2112907971 cites W1997480476 @default.
• W2112907971 cites W1997746246 @default.
• W2112907971 cites W1998238844 @default.
• W2112907971 cites W1999207703 @default.
• W2112907971 cites W2000620255 @default.
• W2112907971 cites W2003245266 @default.
• W2112907971 cites W2004640739 @default.
• W2112907971 cites W2005094593 @default.
• W2112907971 cites W2006699168 @default.
• W2112907971 cites W2007856011 @default.
• W2112907971 cites W2007978409 @default.
• W2112907971 cites W2008684414 @default.
• W2112907971 cites W2009378735 @default.
• W2112907971 cites W2010290700 @default.
• W2112907971 cites W2010466904 @default.
• W2112907971 cites W2011063897 @default.
• W2112907971 cites W2012564250 @default.
• W2112907971 cites W2015820342 @default.
• W2112907971 cites W2016732725 @default.
• W2112907971 cites W2019420347 @default.
• W2112907971 cites W2020246476 @default.
• W2112907971 cites W2021199098 @default.
• W2112907971 cites W2021738918 @default.
• W2112907971 cites W2022502045 @default.
• W2112907971 cites W2024302505 @default.
• W2112907971 cites W2024463180 @default.
• W2112907971 cites W2027613370 @default.
• W2112907971 cites W2030205508 @default.
• W2112907971 cites W2032882684 @default.
• W2112907971 cites W2033218403 @default.
• W2112907971 cites W2033464993 @default.
• W2112907971 cites W2033631070 @default.
• W2112907971 cites W2034487221 @default.
• W2112907971 cites W2035171502 @default.
• W2112907971 cites W2035939622 @default.
• W2112907971 cites W2036806870 @default.
• W2112907971 cites W2036886202 @default.
• W2112907971 cites W2037003935 @default.
• W2112907971 cites W2040222685 @default.
• W2112907971 cites W2040313539 @default.
• W2112907971 cites W2040466820 @default.
• W2112907971 cites W2040502797 @default.
• W2112907971 cites W2041082946 @default.
• W2112907971 cites W2042304504 @default.
• W2112907971 cites W2042486230 @default.
• W2112907971 cites W2042797749 @default.
• W2112907971 cites W2042851494 @default.
• W2112907971 cites W2043236653 @default.
• W2112907971 cites W2043434716 @default.
• W2112907971 cites W2048959161 @default.
• W2112907971 cites W2049725192 @default.
• W2112907971 cites W2049843327 @default.

• next