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• W2113016186 abstract "The Hermes transposable element has been used to genetically transform a wide range of insect species, including the mosquito, Aedes aegypti, a vector of several important human pathogens. Hermes integrations into the mosquito germline are characterized by the non-canonical integration of the transposon and flanking plasmid and, once integrated, Hermes is stable in the presence of its transposase. In an effort to improve the post-integration mobility of Hermes in the germline of Ae. aegypti, a transgenic helper Mos1 construct expressing Hermes transposase under the control of a testis-specific promoter was crossed to a separate transgenic strain containing a target Hermes transposon. In less than 1% of the approximately 1,500 progeny from jumpstarter lines analyzed, evidence of putative Hermes germline remobilizations were detected. These recovered transposition events occur through an aberrant mechanism and provide insight into the non-canonical cut-and-paste transposition of Hermes in the germ line of Ae. aegypti." @default.
• W2113016186 created "2016-06-24" @default.
• W2113016186 creator A5062733069 @default.
• W2113016186 creator A5080704107 @default.
• W2113016186 date "2010-07-03" @default.
• W2113016186 modified "2023-09-26" @default.
• W2113016186 title "Mobility properties of the Hermes transposable element in transgenic lines of Aedes aegypti" @default.
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• W2113016186 doi "https://doi.org/10.1007/s10709-010-9459-7" @default.
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