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- W2113104493 abstract "The primate T-cell lymphoma/leukemia viruses (PTLV) are a subgroup of retroviruses, including human T-cell lymphoma/leukemia viruses types I and II (HTLV-I and HTLV-II) and simian T-cell leukemia virus (STLV-I). The PTLV are a group of plus-sense and single-stranded RNA-containing viruses. The PTLV and bovine leukemia virus, the etiologic agent of enzootic bovine leukemia, form an unnamed genus of retroviruses. One of the characteristics of these four type C viruses is the presence of a conserved epitope in their core proteins. This epitope is absent from all other retroviruses, including human immunodeficiency virus (HIV-1) and HIV-2. Multiple isolates of each of the members of the PTLV have been characterized. The genomic diversity found among HTLV-I isolates from asymptomatic carriers and patients with adult T-cell leukemia/lymphoma and HTLV-I-associated myelopathy from throughout the world exhibits no correlation with the disease, but rather depends on their geographic origin. Polymerase chain reaction using the primer pair, SK110/SK111, has proven to be a sensitive and specific means to detect PTLV infection." @default.
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- W2113104493 date "1995-01-01" @default.
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- W2113104493 title "[24] Estimation of genetic heterogeneity in primate T-cell lymphoma/leukemia viruses by PCR" @default.
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- W2113104493 doi "https://doi.org/10.1016/s1043-9471(06)80102-3" @default.
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