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• W2113113337 abstract "ABSTRACT We investigated the molecular basis of the activity of 4-phenoxyphenoxyethyl thiocyanate (WC-9) against Trypanosoma cruzi , the etiological agent of Chagas’ disease. We found that growth inhibition of T. cruzi epimastigotes induced by this compound was associated with a reduction in the content of the parasite's endogenous sterols due to a specific blockade of their de novo synthesis at the level of squalene synthase." @default.
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• W2113113337 date "2003-06-01" @default.
• W2113113337 modified "2023-10-17" @default.
• W2113113337 title "Mechanism of Action of 4-Phenoxyphenoxyethyl Thiocyanate (WC-9) against <i>Trypanosoma cruzi</i> , the Causative Agent of Chagas’ Disease" @default.
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• W2113113337 doi "https://doi.org/10.1128/aac.47.6.2047-2050.2003" @default.
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