FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2113166942> ?p ?o ?g. }

• W2113166942 endingPage "2208" @default.
• W2113166942 startingPage "2203" @default.
• W2113166942 abstract "Insulin has opposing influences on blood pressure by simultaneously increasing adrenergic activity and vasodilatating peripheral blood vessels. In this study, we sought to determine whether hyperinsulinemia affects tilt table responses in older adults with type 2 diabetes not complicated by orthostatic hypotension.Twenty-two older adults (mean age 71.7 +/- 1.1) with diet-controlled or oral hypoglycemic drug-controlled type 2 diabetes were recruited. All subjects with orthostatic hypotension, diabetic nephropathy, and sensory neuropathy were excluded. Subjects underwent euglycemic-hyperinsulinemic clamp and placebo sham clamp sessions. Sequential euglycemic-hyperinsulinemic clamps were performed for 2 h at 40 mU x m(-2) x min(-1) (low dose) and 2 h at 80 mU x m(-2) x min(-1) (high dose), and each was followed by a head-up tilt table test at 70 degrees C for 10 min.There were no incidents of presyncope during the sham clamp, whereas there were four presyncopal events during both the low-dose and high-dose tilts. Although the low-dose clamp showed no difference in the response between sessions (two-way ANOVA), subjects demonstrated a significantly larger decrease in mean arterial pressure (P = 0.005) and diastolic blood pressure (P = 0.08) during the high-dose tilt. Doppler measures of middle cerebral artery velocity were no different between the two sessions at either dose.The vasodilatory response to insulin can unmask orthostatic intolerance in older adults with type 2 diabetes, resulting in presyncopal symptoms. This could contribute to orthostatic hypotension in combination with other factors such as hyperthermia, hypovolemia, and adverse effects from medications." @default.
• W2113166942 created "2016-06-24" @default.
• W2113166942 creator A5030272062 @default.
• W2113166942 creator A5041713927 @default.
• W2113166942 creator A5046238445 @default.
• W2113166942 creator A5049179752 @default.
• W2113166942 date "2008-08-20" @default.
• W2113166942 modified "2023-09-26" @default.
• W2113166942 title "Euglycemic Hyperinsulinemia Alters the Response to Orthostatic Stress in Older Adults With Type 2 Diabetes" @default.
• W2113166942 cites W1966124808 @default.
• W2113166942 cites W1989330920 @default.
• W2113166942 cites W1997623350 @default.
• W2113166942 cites W2017122536 @default.
• W2113166942 cites W2022065142 @default.
• W2113166942 cites W2023007390 @default.
• W2113166942 cites W2031897978 @default.
• W2113166942 cites W2032974172 @default.
• W2113166942 cites W2065531338 @default.
• W2113166942 cites W2075790801 @default.
• W2113166942 cites W2093011968 @default.
• W2113166942 cites W2095497214 @default.
• W2113166942 cites W2096774244 @default.
• W2113166942 cites W2122879720 @default.
• W2113166942 cites W2139155639 @default.
• W2113166942 cites W2147476476 @default.
• W2113166942 cites W2148395632 @default.
• W2113166942 cites W2164691092 @default.
• W2113166942 cites W2165801681 @default.
• W2113166942 cites W2168588540 @default.
• W2113166942 cites W2204253699 @default.
• W2113166942 cites W2215175225 @default.
• W2113166942 cites W2419135572 @default.
• W2113166942 doi "https://doi.org/10.2337/dc08-1058" @default.
• W2113166942 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2571046" @default.
• W2113166942 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18716048" @default.
• W2113166942 hasPublicationYear "2008" @default.
• W2113166942 type Work @default.
• W2113166942 sameAs 2113166942 @default.
• W2113166942 citedByCount "5" @default.
• W2113166942 countsByYear W21131669422012 @default.
• W2113166942 countsByYear W21131669422015 @default.
• W2113166942 countsByYear W21131669422020 @default.
• W2113166942 crossrefType "journal-article" @default.
• W2113166942 hasAuthorship W2113166942A5030272062 @default.
• W2113166942 hasAuthorship W2113166942A5041713927 @default.
• W2113166942 hasAuthorship W2113166942A5046238445 @default.
• W2113166942 hasAuthorship W2113166942A5049179752 @default.
• W2113166942 hasBestOaLocation W21131669421 @default.
• W2113166942 hasConcept C126322002 @default.
• W2113166942 hasConcept C134018914 @default.
• W2113166942 hasConcept C142724271 @default.
• W2113166942 hasConcept C164705383 @default.
• W2113166942 hasConcept C204787440 @default.
• W2113166942 hasConcept C27081682 @default.
• W2113166942 hasConcept C2777180221 @default.
• W2113166942 hasConcept C2777391703 @default.
• W2113166942 hasConcept C2777953023 @default.
• W2113166942 hasConcept C2778122182 @default.
• W2113166942 hasConcept C2779306644 @default.
• W2113166942 hasConcept C2780988686 @default.
• W2113166942 hasConcept C555293320 @default.
• W2113166942 hasConcept C71924100 @default.
• W2113166942 hasConcept C73787029 @default.
• W2113166942 hasConcept C84393581 @default.
• W2113166942 hasConceptScore W2113166942C126322002 @default.
• W2113166942 hasConceptScore W2113166942C134018914 @default.
• W2113166942 hasConceptScore W2113166942C142724271 @default.
• W2113166942 hasConceptScore W2113166942C164705383 @default.
• W2113166942 hasConceptScore W2113166942C204787440 @default.
• W2113166942 hasConceptScore W2113166942C27081682 @default.
• W2113166942 hasConceptScore W2113166942C2777180221 @default.
• W2113166942 hasConceptScore W2113166942C2777391703 @default.
• W2113166942 hasConceptScore W2113166942C2777953023 @default.
• W2113166942 hasConceptScore W2113166942C2778122182 @default.
• W2113166942 hasConceptScore W2113166942C2779306644 @default.
• W2113166942 hasConceptScore W2113166942C2780988686 @default.
• W2113166942 hasConceptScore W2113166942C555293320 @default.
• W2113166942 hasConceptScore W2113166942C71924100 @default.
• W2113166942 hasConceptScore W2113166942C73787029 @default.
• W2113166942 hasConceptScore W2113166942C84393581 @default.
• W2113166942 hasIssue "11" @default.
• W2113166942 hasLocation W21131669421 @default.
• W2113166942 hasLocation W21131669422 @default.
• W2113166942 hasLocation W21131669423 @default.
• W2113166942 hasLocation W21131669424 @default.
• W2113166942 hasOpenAccess W2113166942 @default.
• W2113166942 hasPrimaryLocation W21131669421 @default.
• W2113166942 hasRelatedWork W1989449228 @default.
• W2113166942 hasRelatedWork W2030111077 @default.
• W2113166942 hasRelatedWork W2033840628 @default.
• W2113166942 hasRelatedWork W2056849036 @default.
• W2113166942 hasRelatedWork W2057434408 @default.
• W2113166942 hasRelatedWork W2070046754 @default.
• W2113166942 hasRelatedWork W2076270866 @default.
• W2113166942 hasRelatedWork W2086423568 @default.
• W2113166942 hasRelatedWork W2145726711 @default.
• W2113166942 hasRelatedWork W2410167096 @default.
• W2113166942 hasVolume "31" @default.

• next