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• W2113167913 abstract "In this study, the authors have generated a tapeworm Taenia solium genomic DNA expression library where foreign peptides/proteins were fused to N-termini of M13 cpVIII and expressed at a high copy number on the phage surface, and they showed that this library may be used in bioselection against antipathogen immune sera, allowing the identification of disease-related antigens recognizing antibodies present in clinical samples. They isolated 2 phage clones expressing T. solium-derived antigens specifically reacting with antibodies present in plasma and cerebrospinal fluid samples of neuroimaging-confirmed neurocysticercosis patients. The described antigen discovery strategy may be used for the direct identification of antigens useful for host-pathogen interaction studies as well as for the development of molecular vaccines and diagnostics." @default.
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• W2113167913 date "2010-12-01" @default.
• W2113167913 modified "2023-10-07" @default.
• W2113167913 title "Isolation of Neurocysticercosis-Related Antigens from a Genomic Phage Display Library of Taenia solium" @default.
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• W2113167913 doi "https://doi.org/10.1177/1087057110385229" @default.
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