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• W2113177771 abstract "Nuclei within myotubes do not synthesize DNA for replication. Accordingly, cultures of myotubes display low levels of DNA polymerase activity. The coincidental decline in DNA polymerase activity and increased formation of multinucleated myotubes during culture does not prove that the loss of capacity to synthesize DNA is a consequence of fusion. Tne experiments described demonstrate that myogenic cells prevented from fusing have low levels of DNA polymerase activity. This is consistent with the notion that, in myogenic cultures, there is a population of mononucleated cells, the myoblasts, which have withdrawn from the mitotic cycle before fusion." @default.
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• W2113177771 date "1978-04-01" @default.
• W2113177771 modified "2023-09-23" @default.
• W2113177771 title "DNA polymerase activity in muscle cultures" @default.
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• W2113177771 doi "https://doi.org/10.1083/jcb.77.1.99" @default.
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