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- W2113201670 abstract "Colon-specific drug delivery has gained increased importance for the delivery of drugs forthe treatment of local diseases associated with the colon. To deliver the compounds in a nondegradedform to the lower part of the gastrointestinal tract, they must first of all pass throughthe stomach, the upper part of the intestine and must use the characteristics of the colon tospecifically release the drugs in this part of the digestive tract. The use of biodegradable polymersholds great promise to achieve targeted drug release to the colon. The family of natural polymershas great appeal to drug delivery as it comprises polymers with a large number of derivatizablegroups, a wide range of molecular weights, varying chemical compositions, low toxicity, andbiodegradability yet high stability. Polysaccharidases are bacterial enzymes that are availablein sufficient quantity to degrade these natural polysaccharides. This article also discusses fewdelivery systems designed to target a drug to the colon." @default.
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- W2113201670 date "2010-01-01" @default.
- W2113201670 modified "2023-09-23" @default.
- W2113201670 title "Role of natural polymers in the development of multiparticulate systems for colon drug targeting" @default.
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- W2113201670 doi "https://doi.org/10.4103/0975-8453.59516" @default.
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