Matches in SemOpenAlex for { <https://semopenalex.org/work/W2113203952> ?p ?o ?g. }
- W2113203952 endingPage "195" @default.
- W2113203952 startingPage "176" @default.
- W2113203952 abstract "Probiotics are known to have a long history of safe use and can be formulated into many different types of products, including foods, drugs, and dietary supplements. Several probiotic microorganisms like genus Lactococcus, Lactobacillus, Streptococcus, Enterococcus, Bifidobacterium, Pediococcus and Propionibacteria spp. are these days used in fermented dairy products and drug formulations. Due to their human consumption, safety of these organisms is of primary importance as their resistance towards antibiotics can be one of the possible threat. The gravity of this issue is further compounded by the possibility of bacteria to transfer resistance determinants horizontally to pathogens and commensal gut microbiota. Antibiotic resistance in these beneficial microbes, either intrinsic or due to any mutation does not manifest a safety concern in itself. Some probiotic strains with intrinsic antibiotic resistance per se could be useful for restoring the gut microbiota after antibiotic treatment. However, specific antibiotic resistance determinants carried on mobile genetic elements, such as tetracycline resistance genes, have often been detected in the typical probiotic genera, and hence constitute a reservoir of resistance for potential food or gut pathogens, thus representing a serious safety issue. Plasmid-associated antibiotic resistance, which occasionally occurs, is a matter of concern as it can be detrimental to use of probiotics owing the possibility of the resistance spreading to harmful microorganisms inhabiting the same niche. Further, the presence of transferable antibiotic resistance genes even to a less innocuous member of the gut microbial community poses a safety hazard and needs to be taken into account. Probiotic safety is beleaguered with the scarcity of well designed and targeted studies and needs to be dealt in right perspective. This review aims to deliberate on the presence of antibiotic resistance in commercially used probiotic organisms and their potential transfer to pathogens and other commensal microbiota present in the gut." @default.
- W2113203952 created "2016-06-24" @default.
- W2113203952 creator A5036314934 @default.
- W2113203952 creator A5071151195 @default.
- W2113203952 creator A5076910935 @default.
- W2113203952 creator A5082540519 @default.
- W2113203952 creator A5091428793 @default.
- W2113203952 date "2014-03-01" @default.
- W2113203952 modified "2023-10-03" @default.
- W2113203952 title "Antibiotic resistance among commercially available probiotics" @default.
- W2113203952 cites W113516409 @default.
- W2113203952 cites W120479784 @default.
- W2113203952 cites W12847493 @default.
- W2113203952 cites W132317415 @default.
- W2113203952 cites W1498136334 @default.
- W2113203952 cites W1571121398 @default.
- W2113203952 cites W1604581007 @default.
- W2113203952 cites W160497574 @default.
- W2113203952 cites W1608674456 @default.
- W2113203952 cites W1610942834 @default.
- W2113203952 cites W161668969 @default.
- W2113203952 cites W1634705979 @default.
- W2113203952 cites W175898283 @default.
- W2113203952 cites W1770841622 @default.
- W2113203952 cites W1829239725 @default.
- W2113203952 cites W1873067796 @default.
- W2113203952 cites W1913824506 @default.
- W2113203952 cites W1960057433 @default.
- W2113203952 cites W1962320437 @default.
- W2113203952 cites W1964168847 @default.
- W2113203952 cites W1965065927 @default.
- W2113203952 cites W1965434356 @default.
- W2113203952 cites W1966108386 @default.
- W2113203952 cites W1966179285 @default.
- W2113203952 cites W1966541668 @default.
- W2113203952 cites W1967748563 @default.
- W2113203952 cites W1969826910 @default.
- W2113203952 cites W1971345505 @default.
- W2113203952 cites W1971737706 @default.
- W2113203952 cites W1975038056 @default.
- W2113203952 cites W1975297222 @default.
- W2113203952 cites W1977539889 @default.
- W2113203952 cites W1978025635 @default.
- W2113203952 cites W1979649609 @default.
- W2113203952 cites W1979781775 @default.
- W2113203952 cites W1980354615 @default.
- W2113203952 cites W1981259465 @default.
- W2113203952 cites W1981342405 @default.
- W2113203952 cites W1982757328 @default.
- W2113203952 cites W1985424114 @default.
- W2113203952 cites W1986695296 @default.
- W2113203952 cites W1987083970 @default.
- W2113203952 cites W1989543959 @default.
- W2113203952 cites W1989820086 @default.
- W2113203952 cites W1990681722 @default.
- W2113203952 cites W1991909139 @default.
- W2113203952 cites W1992579563 @default.
- W2113203952 cites W1992963889 @default.
- W2113203952 cites W1995178144 @default.
- W2113203952 cites W1995810839 @default.
- W2113203952 cites W1997043141 @default.
- W2113203952 cites W1997925619 @default.
- W2113203952 cites W1997989258 @default.
- W2113203952 cites W1999267716 @default.
- W2113203952 cites W1999850374 @default.
- W2113203952 cites W2000152285 @default.
- W2113203952 cites W2000434235 @default.
- W2113203952 cites W2000804003 @default.
- W2113203952 cites W2001808472 @default.
- W2113203952 cites W2001852290 @default.
- W2113203952 cites W2002446883 @default.
- W2113203952 cites W2003768916 @default.
- W2113203952 cites W2004457452 @default.
- W2113203952 cites W2006340521 @default.
- W2113203952 cites W2007299159 @default.
- W2113203952 cites W2007628934 @default.
- W2113203952 cites W2007838481 @default.
- W2113203952 cites W2008443243 @default.
- W2113203952 cites W2009301118 @default.
- W2113203952 cites W2010360751 @default.
- W2113203952 cites W2011683757 @default.
- W2113203952 cites W2013785326 @default.
- W2113203952 cites W2013875825 @default.
- W2113203952 cites W2014088902 @default.
- W2113203952 cites W2016928058 @default.
- W2113203952 cites W2021055155 @default.
- W2113203952 cites W2021155703 @default.
- W2113203952 cites W2022080631 @default.
- W2113203952 cites W2025382728 @default.
- W2113203952 cites W2026221526 @default.
- W2113203952 cites W2026720129 @default.
- W2113203952 cites W2030537885 @default.
- W2113203952 cites W2031232438 @default.
- W2113203952 cites W2031886686 @default.
- W2113203952 cites W2032605132 @default.
- W2113203952 cites W2032658734 @default.
- W2113203952 cites W2033853013 @default.
- W2113203952 cites W2035639398 @default.