FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2113257084> ?p ?o ?g. }

• W2113257084 endingPage "3628" @default.
• W2113257084 startingPage "3617" @default.
• W2113257084 abstract "In the rat neocortex, a subset of GABAergic interneurons express the neuropeptide vasoactive intestinal peptide (VIP). Previously, we demonstrated that a population of VIPergic interneurons could be accurately identified by their irregular spiking (IS) pattern and their bipolar morphology. IS interneurons were studied in neocortical slices from 16-22-day-old rats using whole-cell recordings, intracellular labelling and single-cell RT-PCR. In response to a depolarizing pulse, IS interneurons typically discharged a burst of action potentials followed by spikes emitted at an irregular frequency. Several seconds of depolarization, micromolar concentrations of 4-aminopyridine, and nanomolar concentrations of either dendrotoxin I or K converted this irregular pattern to a sustained discharge, suggesting the involvement of an ID-like K+ current. The main glutamate receptor subunits detected in IS cells were GluR1 flop and GluR2 flop, GluR5 and GluR6, and NR2B and NR2D for the alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid (AMPA), kainate and N-methyl-D-aspartic acid (NMDA) subtypes, respectively. Paired whole-cell patch-clamp recordings indicated that pyramidal neurons provide intracortical glutamatergic inputs onto IS interneurons. Most connections had high probabilities of response and exhibited frequency-dependent paired pulse depression. Comparison of the amplitude distribution of paired responses suggested that most of these connections consisted of multiple functional release sites. Finally, two discrete subpopulations of IS cells could be identified based on the duration of the initial burst of action potentials and the differential expression of calretinin and choline acetyltransferase." @default.
• W2113257084 created "2016-06-24" @default.
• W2113257084 creator A5014239283 @default.
• W2113257084 creator A5019891892 @default.
• W2113257084 creator A5051755979 @default.
• W2113257084 creator A5053471168 @default.
• W2113257084 creator A5057419092 @default.
• W2113257084 creator A5074586431 @default.
• W2113257084 date "1998-12-01" @default.
• W2113257084 modified "2023-10-18" @default.
• W2113257084 title "Properties of bipolar VIPergic interneurons and their excitation by pyramidal neurons in the rat neocortex" @default.
• W2113257084 cites W1508710284 @default.
• W2113257084 cites W1511174464 @default.
• W2113257084 cites W1518098954 @default.
• W2113257084 cites W1572972152 @default.
• W2113257084 cites W1577757039 @default.
• W2113257084 cites W1587291620 @default.
• W2113257084 cites W1588326218 @default.
• W2113257084 cites W1605336512 @default.
• W2113257084 cites W1784965721 @default.
• W2113257084 cites W1927932324 @default.
• W2113257084 cites W1948270772 @default.
• W2113257084 cites W1963945272 @default.
• W2113257084 cites W1965911542 @default.
• W2113257084 cites W1966644204 @default.
• W2113257084 cites W1967706364 @default.
• W2113257084 cites W1971405760 @default.
• W2113257084 cites W1972182945 @default.
• W2113257084 cites W1974424738 @default.
• W2113257084 cites W1976763631 @default.
• W2113257084 cites W1982231538 @default.
• W2113257084 cites W1983477206 @default.
• W2113257084 cites W1983668127 @default.
• W2113257084 cites W1984049384 @default.
• W2113257084 cites W1985658748 @default.
• W2113257084 cites W1996108053 @default.
• W2113257084 cites W1997862361 @default.
• W2113257084 cites W2012529293 @default.
• W2113257084 cites W2013427111 @default.
• W2113257084 cites W2013966508 @default.
• W2113257084 cites W2023182720 @default.
• W2113257084 cites W2023654689 @default.
• W2113257084 cites W2031538300 @default.
• W2113257084 cites W2032350393 @default.
• W2113257084 cites W2037593266 @default.
• W2113257084 cites W2038054975 @default.
• W2113257084 cites W2041512062 @default.
• W2113257084 cites W2041848975 @default.
• W2113257084 cites W2046281188 @default.
• W2113257084 cites W2046868433 @default.
• W2113257084 cites W2053794249 @default.
• W2113257084 cites W2059392118 @default.
• W2113257084 cites W2060941733 @default.
• W2113257084 cites W2061854524 @default.
• W2113257084 cites W2065169750 @default.
• W2113257084 cites W2067334833 @default.
• W2113257084 cites W2068961574 @default.
• W2113257084 cites W2079026774 @default.
• W2113257084 cites W2091640515 @default.
• W2113257084 cites W2093427801 @default.
• W2113257084 cites W2095561971 @default.
• W2113257084 cites W2100327381 @default.
• W2113257084 cites W2108119444 @default.
• W2113257084 cites W2110534885 @default.
• W2113257084 cites W2139973055 @default.
• W2113257084 cites W2161729720 @default.
• W2113257084 cites W2166901944 @default.
• W2113257084 cites W2323067478 @default.
• W2113257084 cites W2414752808 @default.
• W2113257084 cites W4294216491 @default.
• W2113257084 cites W642033537 @default.
• W2113257084 cites W2185212694 @default.
• W2113257084 doi "https://doi.org/10.1046/j.1460-9568.1998.00367.x" @default.
• W2113257084 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9875341" @default.
• W2113257084 hasPublicationYear "1998" @default.
• W2113257084 type Work @default.
• W2113257084 sameAs 2113257084 @default.
• W2113257084 citedByCount "153" @default.
• W2113257084 countsByYear W21132570842012 @default.
• W2113257084 countsByYear W21132570842013 @default.
• W2113257084 countsByYear W21132570842014 @default.
• W2113257084 countsByYear W21132570842015 @default.
• W2113257084 countsByYear W21132570842016 @default.
• W2113257084 countsByYear W21132570842017 @default.
• W2113257084 countsByYear W21132570842018 @default.
• W2113257084 countsByYear W21132570842019 @default.
• W2113257084 countsByYear W21132570842020 @default.
• W2113257084 countsByYear W21132570842021 @default.
• W2113257084 countsByYear W21132570842022 @default.
• W2113257084 countsByYear W21132570842023 @default.
• W2113257084 crossrefType "journal-article" @default.
• W2113257084 hasAuthorship W2113257084A5014239283 @default.
• W2113257084 hasAuthorship W2113257084A5019891892 @default.
• W2113257084 hasAuthorship W2113257084A5051755979 @default.
• W2113257084 hasAuthorship W2113257084A5053471168 @default.
• W2113257084 hasAuthorship W2113257084A5057419092 @default.
• W2113257084 hasAuthorship W2113257084A5074586431 @default.
• W2113257084 hasConcept C112592302 @default.

• next