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• W2113287462 abstract "The prevalence of obstructive sleep apnea (OSA) is 3% to 7% in the general population [ [1] Barbe F. Duran-Cantolla J. Sanchez-de-la-Torre M. et al. Effect of continuous positive airway pressure on the incidence of hypertension and cardiovascular events in nonsleepy patients with obstructive sleep apnea: a randomized controlled trial. JAMA. 2012; 307: 2161-2168 Crossref PubMed Scopus (593) Google Scholar ]. OSA has been found to be associated with cardiovascular disease, leading to high rates of morbidity and mortality [ [2] Wang X. Ouyang Y. Wang Z. et al. Obstructive sleep apnea and risk of cardiovascular disease and all-cause mortality: a meta-analysis of prospective cohort studies. Int. J. Cardiol. 2013; 169: 207-214 Abstract Full Text Full Text PDF PubMed Scopus (206) Google Scholar ]. Dong et al. reported that moderate to severe OSA significantly increased cardiovascular risk, particularly the risk of stroke [ [3] Dong J.Y. Zhang Y.H. Qin L.Q. Obstructive sleep apnea and cardiovascular risk: meta-analysis of prospective cohort studies. Atherosclerosis. 2013; 229: 489-495 Abstract Full Text Full Text PDF PubMed Scopus (202) Google Scholar ]. Continuous positive airway pressure (CPAP) therapy can correct airway obstruction so to improve the quality of nighttime sleep in patients with OSA [ [1] Barbe F. Duran-Cantolla J. Sanchez-de-la-Torre M. et al. Effect of continuous positive airway pressure on the incidence of hypertension and cardiovascular events in nonsleepy patients with obstructive sleep apnea: a randomized controlled trial. JAMA. 2012; 307: 2161-2168 Crossref PubMed Scopus (593) Google Scholar ]. It is considered as the first-line therapy for severe OSA [ [4] Anandam A. Patil M. Akinnusi M. et al. Cardiovascular mortality in obstructive sleep apnoea treated with continuous positive airway pressure or oral appliance: an observational study. Respirology. 2013; 18: 1184-1190 Crossref PubMed Scopus (99) Google Scholar ]. However, the cardiovascular outcomes in patients undergoing CPAP therapy remain unclear. The purpose of this meta-analysis is to investigate the effects of CPAP therapy on the incidence of cardiovascular death and non-fatal cardiovascular events in patients with OSA, particularly in patients with moderate to severe OSA (apnea–hypopnea index, AHI ≥ 20)." @default.
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• W2113287462 date "2015-07-01" @default.
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• W2113287462 title "Continuous positive airway pressure treatment reduces cardiovascular death and non-fatal cardiovascular events in patients with obstructive sleep apnea: A meta-analysis of 11 studies" @default.
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• W2113287462 doi "https://doi.org/10.1016/j.ijcard.2015.05.003" @default.
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