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• W2113313289 startingPage "228" @default.
• W2113313289 abstract "The balance between oxidation and antioxidation is believed to be critical in maintaining healthy biological systems. Under physiological conditions, the human antioxidative defense system including e.g., superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione (GSH) and others, allows the elimination of excess reactive oxygen species (ROS) including, among others superoxide anions (O 2 .- ), hydroxyl radicals (OH . ), alkoxyl radicals (RO . ) and peroxyradicals (ROO . ). However, our endogenous antioxidant defense systems are incomplete without exogenous originating reducing compounds such as vitamin C, vitamin E, carotenoids and polyphenols, playing an essential role in many antioxidant mechanisms in living organisms. Therefore, there is continuous demand for exogenous antioxidants in order to prevent oxidative stress, representing a disequilibrium redox state in favor of oxidation. However, high doses of isolated compounds may be toxic, owing to prooxidative effects at high concentrations or their potential to react with beneficial concentrations of ROS normally present at physiological conditions that are required for optimal cellular functioning. This review aims to examine the double-edged effects of dietary originating antioxidants with a focus on the most abundant compounds, especially polyphenols, vitamin C, vitamin E and carotenoids. Different approaches to enrich our body with exogenous antioxidants such as via synthetic antioxidants, diets rich in fruits and vegetables and taking supplements will be reviewed and experimental and epidemiological evidences discussed, highlighting that antioxidants at physiological doses are generally safe, exhibiting interesting health beneficial effects." @default.
• W2113313289 created "2016-06-24" @default.
• W2113313289 creator A5021428615 @default.
• W2113313289 creator A5081220483 @default.
• W2113313289 date "2010-01-01" @default.
• W2113313289 modified "2023-10-17" @default.
• W2113313289 title "Exogenous Antioxidants—Double-Edged Swords in Cellular Redox State: Health Beneficial Effects at Physiologic Doses versus Deleterious Effects at High Doses" @default.
• W2113313289 cites W1508194135 @default.
• W2113313289 cites W1525444530 @default.
• W2113313289 cites W1536161802 @default.
• W2113313289 cites W1539954440 @default.
• W2113313289 cites W1566419077 @default.
• W2113313289 cites W1734082729 @default.
• W2113313289 cites W1794856894 @default.
• W2113313289 cites W1826417692 @default.
• W2113313289 cites W1830431811 @default.
• W2113313289 cites W1844983325 @default.
• W2113313289 cites W1873241517 @default.
• W2113313289 cites W1912855510 @default.
• W2113313289 cites W1914622032 @default.
• W2113313289 cites W1934399226 @default.
• W2113313289 cites W1934614516 @default.
• W2113313289 cites W1956492339 @default.
• W2113313289 cites W1966114904 @default.
• W2113313289 cites W1967024416 @default.
• W2113313289 cites W1967322292 @default.
• W2113313289 cites W1973058491 @default.
• W2113313289 cites W1974125717 @default.
• W2113313289 cites W1977694127 @default.
• W2113313289 cites W1977817925 @default.
• W2113313289 cites W1979182110 @default.
• W2113313289 cites W1979422808 @default.
• W2113313289 cites W1980248989 @default.
• W2113313289 cites W1980790707 @default.
• W2113313289 cites W1981184057 @default.
• W2113313289 cites W1983676612 @default.
• W2113313289 cites W1983763398 @default.
• W2113313289 cites W1983975895 @default.
• W2113313289 cites W1984769982 @default.
• W2113313289 cites W1989391366 @default.
• W2113313289 cites W1992367553 @default.
• W2113313289 cites W1993269912 @default.
• W2113313289 cites W1994801797 @default.
• W2113313289 cites W1999141231 @default.
• W2113313289 cites W1999575328 @default.
• W2113313289 cites W1999635152 @default.
• W2113313289 cites W2000181213 @default.
• W2113313289 cites W2004794022 @default.
• W2113313289 cites W2005728324 @default.
• W2113313289 cites W2006733921 @default.
• W2113313289 cites W2007649442 @default.
• W2113313289 cites W2008541273 @default.
• W2113313289 cites W2012508579 @default.
• W2113313289 cites W2015671168 @default.
• W2113313289 cites W2023536393 @default.
• W2113313289 cites W2024627370 @default.
• W2113313289 cites W2027651810 @default.
• W2113313289 cites W2029124200 @default.
• W2113313289 cites W2029416355 @default.
• W2113313289 cites W2029928510 @default.
• W2113313289 cites W2032094068 @default.
• W2113313289 cites W2032955106 @default.
• W2113313289 cites W2039322367 @default.
• W2113313289 cites W2042031496 @default.
• W2113313289 cites W2042902935 @default.
• W2113313289 cites W2043363945 @default.
• W2113313289 cites W2043523758 @default.
• W2113313289 cites W2043876718 @default.
• W2113313289 cites W2046606445 @default.
• W2113313289 cites W2047447331 @default.
• W2113313289 cites W2052257773 @default.
• W2113313289 cites W2056266253 @default.
• W2113313289 cites W2056926634 @default.
• W2113313289 cites W2057453845 @default.
• W2113313289 cites W2059571578 @default.
• W2113313289 cites W2060075831 @default.
• W2113313289 cites W2060132479 @default.
• W2113313289 cites W2061142443 @default.
• W2113313289 cites W2062502442 @default.
• W2113313289 cites W2062721109 @default.
• W2113313289 cites W2066710019 @default.
• W2113313289 cites W2068529963 @default.
• W2113313289 cites W2069518712 @default.
• W2113313289 cites W2074802791 @default.
• W2113313289 cites W2076358165 @default.
• W2113313289 cites W2078166953 @default.
• W2113313289 cites W2080312876 @default.
• W2113313289 cites W2080647743 @default.
• W2113313289 cites W2082473468 @default.
• W2113313289 cites W2084220890 @default.
• W2113313289 cites W2086381409 @default.
• W2113313289 cites W2086498426 @default.
• W2113313289 cites W2086959952 @default.
• W2113313289 cites W2087257363 @default.
• W2113313289 cites W2089242037 @default.
• W2113313289 cites W2089522175 @default.
• W2113313289 cites W2091783295 @default.
• W2113313289 cites W2099680167 @default.

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