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- W2113328122 abstract "The cellular immune response to respiratory syncytial virus (RSV) infection was examined in infants aged 1–21 months who were hospitalized because of RSV infection or non-RSV-related illness. RSV- or control-stimulated peripheral blood mononuclear cells were examined to determine RSV-specific intracellular T helper-1 (Th1) and T helper- 2 (Th2) cytokine expression, chemokine messenger RNA (mRNA) expression, and cell surface markers. Patients hospitalized because of RSV infection had increased numbers of CD16+ and CD56bright cells and had RSV-specific increases in Th1 (interleukin [IL]-2 and interferon-γ) and Th2 (IL-4 and IL-6) cytokines and CC chemokines (macrophage inflammatory protein [MIP]-1α, MIP-1β, and RANTES [regulated on activation, normally T cell expressed and secreted]) mRNA expression. The results suggest that RSV infection induces both Th1 and Th2 cytokine expression and CC chemokine expression." @default.
- W2113328122 created "2016-06-24" @default.
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- W2113328122 date "2002-05-15" @default.
- W2113328122 modified "2023-09-23" @default.
- W2113328122 title "Peripheral Blood Mononuclear Cells from Infants Hospitalized Because of Respiratory Syncytial Virus Infection Express T Helper–1 and T Helper–2 Cytokines and CC Chemokine Messenger RNA" @default.
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- W2113328122 doi "https://doi.org/10.1086/340505" @default.
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