Matches in SemOpenAlex for { <https://semopenalex.org/work/W2113361567> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2113361567 endingPage "1" @default.
- W2113361567 startingPage "1" @default.
- W2113361567 abstract "Background: Clinical and experimental findings suggest that Obsessive-Compulsive Disorder (OCD) is due to an abnormality of the cortico-striato-thalamo-cortical circuit. Bradykinesia and mental slowness can be present in patients with basal ganglia disorders affecting the cortico-striato-thalamo-cortical circuit. Aim of this study is to investigate whether bradykinesia and mental slowness are present in patients with OCD. Methods: Participants comprised 19 non-depressed anti-psychotic free patients with OCD. Bradykinesia was assessed with the motor section of the Unified Parkinson's Disease Rating Scale (UPDRS). Mental slowness was investigated with the WAIS-R and the Y-BOCS. Psychiatric evaluation was performed with: SCID-I, Y-BOCS, HAMD, HAM-A, and MMPI. Cognitive functions were assessed with the WAIS-R. Results: Bradykinesia and mental slowness were present respectively in the 39% and 89% of the patients. Bradykinesia was positively correlated to Y-BOCS mental slowness score (rho=0.48, p< 0.05), and inversely related to the WAIS-R Performance IQ score (rho=-0.65, p< 0.01). Patients with bradykinesia scored significantly lower in the Similarities and Digit symbol coding WAIS-R subscales as compared to non-bradykinetic patients. in our sample pathological doubt was not associated with IQ measures nor with bradykinesia. Twelve out of 19 patients (63%) showed impairments in the nonverbal function scores. Conclusions: The novel findings of this study is that bradykinesia can be present in patients with OCD, and it is correlated with mental slowness and nonverbal performance impairment. These preliminary data support the notion that dysfunction of basal ganglia is possibly present in OCD patients." @default.
- W2113361567 created "2016-06-24" @default.
- W2113361567 creator A5003438194 @default.
- W2113361567 creator A5010035939 @default.
- W2113361567 creator A5011405857 @default.
- W2113361567 creator A5019766683 @default.
- W2113361567 creator A5025525821 @default.
- W2113361567 creator A5027858233 @default.
- W2113361567 creator A5055565600 @default.
- W2113361567 creator A5086577999 @default.
- W2113361567 creator A5089513945 @default.
- W2113361567 date "2009-01-01" @default.
- W2113361567 modified "2023-09-24" @default.
- W2113361567 title "Bradykinesia and Mental Slowness in Patients with Obsessive-compulsive Disorder" @default.
- W2113361567 doi "https://doi.org/10.1016/s0924-9338(09)71268-4" @default.
- W2113361567 hasPublicationYear "2009" @default.
- W2113361567 type Work @default.
- W2113361567 sameAs 2113361567 @default.
- W2113361567 citedByCount "1" @default.
- W2113361567 crossrefType "journal-article" @default.
- W2113361567 hasAuthorship W2113361567A5003438194 @default.
- W2113361567 hasAuthorship W2113361567A5010035939 @default.
- W2113361567 hasAuthorship W2113361567A5011405857 @default.
- W2113361567 hasAuthorship W2113361567A5019766683 @default.
- W2113361567 hasAuthorship W2113361567A5025525821 @default.
- W2113361567 hasAuthorship W2113361567A5027858233 @default.
- W2113361567 hasAuthorship W2113361567A5055565600 @default.
- W2113361567 hasAuthorship W2113361567A5086577999 @default.
- W2113361567 hasAuthorship W2113361567A5089513945 @default.
- W2113361567 hasBestOaLocation W21133615671 @default.
- W2113361567 hasConcept C118552586 @default.
- W2113361567 hasConcept C11940443 @default.
- W2113361567 hasConcept C121332964 @default.
- W2113361567 hasConcept C138496976 @default.
- W2113361567 hasConcept C15744967 @default.
- W2113361567 hasConcept C169900460 @default.
- W2113361567 hasConcept C2777198177 @default.
- W2113361567 hasConcept C548259974 @default.
- W2113361567 hasConcept C62520636 @default.
- W2113361567 hasConcept C71924100 @default.
- W2113361567 hasConcept C83849319 @default.
- W2113361567 hasConcept C89798072 @default.
- W2113361567 hasConceptScore W2113361567C118552586 @default.
- W2113361567 hasConceptScore W2113361567C11940443 @default.
- W2113361567 hasConceptScore W2113361567C121332964 @default.
- W2113361567 hasConceptScore W2113361567C138496976 @default.
- W2113361567 hasConceptScore W2113361567C15744967 @default.
- W2113361567 hasConceptScore W2113361567C169900460 @default.
- W2113361567 hasConceptScore W2113361567C2777198177 @default.
- W2113361567 hasConceptScore W2113361567C548259974 @default.
- W2113361567 hasConceptScore W2113361567C62520636 @default.
- W2113361567 hasConceptScore W2113361567C71924100 @default.
- W2113361567 hasConceptScore W2113361567C83849319 @default.
- W2113361567 hasConceptScore W2113361567C89798072 @default.
- W2113361567 hasIssue "S1" @default.
- W2113361567 hasLocation W21133615671 @default.
- W2113361567 hasOpenAccess W2113361567 @default.
- W2113361567 hasPrimaryLocation W21133615671 @default.
- W2113361567 hasRelatedWork W2001312823 @default.
- W2113361567 hasRelatedWork W2352657732 @default.
- W2113361567 hasRelatedWork W2359087400 @default.
- W2113361567 hasRelatedWork W2374582240 @default.
- W2113361567 hasRelatedWork W2381669092 @default.
- W2113361567 hasRelatedWork W2387296384 @default.
- W2113361567 hasRelatedWork W2392788791 @default.
- W2113361567 hasRelatedWork W2460552153 @default.
- W2113361567 hasRelatedWork W2758937401 @default.
- W2113361567 hasRelatedWork W2891149965 @default.
- W2113361567 hasVolume "24" @default.
- W2113361567 isParatext "false" @default.
- W2113361567 isRetracted "false" @default.
- W2113361567 magId "2113361567" @default.
- W2113361567 workType "article" @default.