FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2113430775> ?p ?o ?g. }

• W2113430775 endingPage "1590" @default.
• W2113430775 startingPage "1581" @default.
• W2113430775 abstract "We used the budding yeast Saccharomyces cerevisiae to ask how elevated mutation rates affect the evolution of asexual eukaryotic populations. Mismatch repair defective and nonmutator strains were competed during adaptation to four laboratory environments (rich medium, low glucose, high salt, and a nonfermentable carbon source).In diploids, mutators have an advantage over nonmutators in all conditions, and mutators that win competitions are on average fitter than nonmutator winners. In contrast, haploid mutators have no advantage when competed against haploid nonmutators, and haploid mutator winners are less fit than nonmutator winners. The diploid mutator winners were all superior to their ancestors both in the condition they had adapted to, and in two of the other conditions. This phenotype was due to a mutation or class of mutations that confers a large growth advantage during the respiratory phase of yeast cultures that precedes stationary phase. This generalist mutation(s) was not selected in diploid nonmutator strains or in haploid strains, which adapt primarily by fixing specialist (condition-specific) mutations. In diploid mutators, such mutations also occur, and the majority accumulates after the fixation of the generalist mutation.We conclude that the advantage of mutators depends on ploidy and that diploid mutators can give rise to beneficial mutations that are inaccessible to nonmutators and haploid mutators." @default.
• W2113430775 created "2016-06-24" @default.
• W2113430775 creator A5020634412 @default.
• W2113430775 creator A5048267912 @default.
• W2113430775 creator A5051640845 @default.
• W2113430775 date "2006-08-01" @default.
• W2113430775 modified "2023-09-26" @default.
• W2113430775 title "Ploidy Controls the Success of Mutators and Nature of Mutations during Budding Yeast Evolution" @default.
• W2113430775 cites W1550165896 @default.
• W2113430775 cites W1566245339 @default.
• W2113430775 cites W1842944877 @default.
• W2113430775 cites W1875033836 @default.
• W2113430775 cites W1955582561 @default.
• W2113430775 cites W1967600116 @default.
• W2113430775 cites W1968917541 @default.
• W2113430775 cites W2003867855 @default.
• W2113430775 cites W2004227844 @default.
• W2113430775 cites W2015973401 @default.
• W2113430775 cites W2020667072 @default.
• W2113430775 cites W2046928699 @default.
• W2113430775 cites W2049718034 @default.
• W2113430775 cites W2054755820 @default.
• W2113430775 cites W2069780164 @default.
• W2113430775 cites W2079013905 @default.
• W2113430775 cites W2097423540 @default.
• W2113430775 cites W2099218800 @default.
• W2113430775 cites W2104263071 @default.
• W2113430775 cites W2104566573 @default.
• W2113430775 cites W2112239989 @default.
• W2113430775 cites W2112570446 @default.
• W2113430775 cites W2112945902 @default.
• W2113430775 cites W2114968751 @default.
• W2113430775 cites W2122340450 @default.
• W2113430775 cites W2127305172 @default.
• W2113430775 cites W2131055368 @default.
• W2113430775 cites W2132691934 @default.
• W2113430775 cites W2148803605 @default.
• W2113430775 cites W2162269532 @default.
• W2113430775 cites W2164832298 @default.
• W2113430775 cites W2181660414 @default.
• W2113430775 cites W2314489802 @default.
• W2113430775 cites W4242420451 @default.
• W2113430775 doi "https://doi.org/10.1016/j.cub.2006.06.070" @default.
• W2113430775 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16920619" @default.
• W2113430775 hasPublicationYear "2006" @default.
• W2113430775 type Work @default.
• W2113430775 sameAs 2113430775 @default.
• W2113430775 citedByCount "88" @default.
• W2113430775 countsByYear W21134307752012 @default.
• W2113430775 countsByYear W21134307752013 @default.
• W2113430775 countsByYear W21134307752014 @default.
• W2113430775 countsByYear W21134307752015 @default.
• W2113430775 countsByYear W21134307752016 @default.
• W2113430775 countsByYear W21134307752017 @default.
• W2113430775 countsByYear W21134307752018 @default.
• W2113430775 countsByYear W21134307752019 @default.
• W2113430775 countsByYear W21134307752020 @default.
• W2113430775 countsByYear W21134307752021 @default.
• W2113430775 countsByYear W21134307752022 @default.
• W2113430775 countsByYear W21134307752023 @default.
• W2113430775 crossrefType "journal-article" @default.
• W2113430775 hasAuthorship W2113430775A5020634412 @default.
• W2113430775 hasAuthorship W2113430775A5048267912 @default.
• W2113430775 hasAuthorship W2113430775A5051640845 @default.
• W2113430775 hasBestOaLocation W21134307751 @default.
• W2113430775 hasConcept C104317684 @default.
• W2113430775 hasConcept C127716648 @default.
• W2113430775 hasConcept C139807058 @default.
• W2113430775 hasConcept C143191323 @default.
• W2113430775 hasConcept C146249460 @default.
• W2113430775 hasConcept C169760540 @default.
• W2113430775 hasConcept C2777576037 @default.
• W2113430775 hasConcept C2779222958 @default.
• W2113430775 hasConcept C501734568 @default.
• W2113430775 hasConcept C54355233 @default.
• W2113430775 hasConcept C78458016 @default.
• W2113430775 hasConcept C86803240 @default.
• W2113430775 hasConcept C98638677 @default.
• W2113430775 hasConceptScore W2113430775C104317684 @default.
• W2113430775 hasConceptScore W2113430775C127716648 @default.
• W2113430775 hasConceptScore W2113430775C139807058 @default.
• W2113430775 hasConceptScore W2113430775C143191323 @default.
• W2113430775 hasConceptScore W2113430775C146249460 @default.
• W2113430775 hasConceptScore W2113430775C169760540 @default.
• W2113430775 hasConceptScore W2113430775C2777576037 @default.
• W2113430775 hasConceptScore W2113430775C2779222958 @default.
• W2113430775 hasConceptScore W2113430775C501734568 @default.
• W2113430775 hasConceptScore W2113430775C54355233 @default.
• W2113430775 hasConceptScore W2113430775C78458016 @default.
• W2113430775 hasConceptScore W2113430775C86803240 @default.
• W2113430775 hasConceptScore W2113430775C98638677 @default.
• W2113430775 hasIssue "16" @default.
• W2113430775 hasLocation W21134307751 @default.
• W2113430775 hasLocation W21134307752 @default.
• W2113430775 hasOpenAccess W2113430775 @default.
• W2113430775 hasPrimaryLocation W21134307751 @default.
• W2113430775 hasRelatedWork W1911318042 @default.
• W2113430775 hasRelatedWork W2011834904 @default.

• next