FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2113443314> ?p ?o ?g. }

• W2113443314 endingPage "1955" @default.
• W2113443314 startingPage "1955" @default.
• W2113443314 abstract "Reduction of gastric acid secretion by acid-suppressive therapy allows pathogen colonization from the upper gastrointestinal tract. The bacteria and viruses in the contaminated stomach have been identified as species from the oral cavity.To examine the association between the use of acid-suppressive drugs and occurrence of community-acquired pneumonia.Incident acid-suppressive drug users with at least 1 year of valid database history were identified from the Integrated Primary Care Information database between January 1, 1995, and December 31, 2002. Incidence rates for pneumonia were calculated for unexposed and exposed individuals. To reduce confounding by indication, a case-control analysis was conducted nested in a cohort of incident users of acid-suppressive drugs. Cases were all individuals with incident pneumonia during or after stopping use of acid-suppressive drugs. Up to 10 controls were matched to each case for practice, year of birth, sex, and index date. Conditional logistic regression was used to compare the risk of community-acquired pneumonia between use of proton pump inhibitors (PPIs) and H2-receptor antagonists.Community-acquired pneumonia defined as certain (proven by radiography or sputum culture) or probable (clinical symptoms consistent with pneumonia).The study population comprised 364,683 individuals who developed 5551 first occurrences of pneumonia during follow-up. The incidence rates of pneumonia in non-acid-suppressive drug users and acid-suppressive drug users were 0.6 and 2.45 per 100 person-years, respectively. The adjusted relative risk for pneumonia among persons currently using PPIs compared with those who stopped using PPIs was 1.89 (95% confidence interval, 1.36-2.62). Current users of H2-receptor antagonists had a 1.63-fold increased risk of pneumonia (95% confidence interval, 1.07-2.48) compared with those who stopped use. For current PPI users, a significant positive dose-response relationship was observed. For H2-receptor antagonist users, the variation in dose was restricted.Current use of gastric acid-suppressive therapy was associated with an increased risk of community-acquired pneumonia." @default.
• W2113443314 created "2016-06-24" @default.
• W2113443314 creator A5011711127 @default.
• W2113443314 creator A5026232773 @default.
• W2113443314 creator A5026522986 @default.
• W2113443314 creator A5029080795 @default.
• W2113443314 creator A5036713064 @default.
• W2113443314 creator A5064234349 @default.
• W2113443314 date "2004-10-27" @default.
• W2113443314 modified "2023-10-14" @default.
• W2113443314 title "Risk of Community-Acquired Pneumonia and Use of Gastric Acid–Suppressive Drugs" @default.
• W2113443314 cites W1906634571 @default.
• W2113443314 cites W1967286718 @default.
• W2113443314 cites W1973398570 @default.
• W2113443314 cites W1973590255 @default.
• W2113443314 cites W1975118460 @default.
• W2113443314 cites W1979583721 @default.
• W2113443314 cites W1989992353 @default.
• W2113443314 cites W1991996972 @default.
• W2113443314 cites W2000315885 @default.
• W2113443314 cites W2004125016 @default.
• W2113443314 cites W2007414499 @default.
• W2113443314 cites W2016854628 @default.
• W2113443314 cites W2037712857 @default.
• W2113443314 cites W2041693213 @default.
• W2113443314 cites W2045861148 @default.
• W2113443314 cites W2072784728 @default.
• W2113443314 cites W2077747080 @default.
• W2113443314 cites W2079267688 @default.
• W2113443314 cites W2081206641 @default.
• W2113443314 cites W2087916586 @default.
• W2113443314 cites W2098291219 @default.
• W2113443314 cites W2100084977 @default.
• W2113443314 cites W2135294786 @default.
• W2113443314 cites W2169245702 @default.
• W2113443314 cites W28670821 @default.
• W2113443314 cites W3143755808 @default.
• W2113443314 doi "https://doi.org/10.1001/jama.292.16.1955" @default.
• W2113443314 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15507580" @default.
• W2113443314 hasPublicationYear "2004" @default.
• W2113443314 type Work @default.
• W2113443314 sameAs 2113443314 @default.
• W2113443314 citedByCount "783" @default.
• W2113443314 countsByYear W21134433142012 @default.
• W2113443314 countsByYear W21134433142013 @default.
• W2113443314 countsByYear W21134433142014 @default.
• W2113443314 countsByYear W21134433142015 @default.
• W2113443314 countsByYear W21134433142016 @default.
• W2113443314 countsByYear W21134433142017 @default.
• W2113443314 countsByYear W21134433142018 @default.
• W2113443314 countsByYear W21134433142019 @default.
• W2113443314 countsByYear W21134433142020 @default.
• W2113443314 countsByYear W21134433142021 @default.
• W2113443314 countsByYear W21134433142022 @default.
• W2113443314 countsByYear W21134433142023 @default.
• W2113443314 crossrefType "journal-article" @default.
• W2113443314 hasAuthorship W2113443314A5011711127 @default.
• W2113443314 hasAuthorship W2113443314A5026232773 @default.
• W2113443314 hasAuthorship W2113443314A5026522986 @default.
• W2113443314 hasAuthorship W2113443314A5029080795 @default.
• W2113443314 hasAuthorship W2113443314A5036713064 @default.
• W2113443314 hasAuthorship W2113443314A5064234349 @default.
• W2113443314 hasBestOaLocation W21134433141 @default.
• W2113443314 hasConcept C120665830 @default.
• W2113443314 hasConcept C121332964 @default.
• W2113443314 hasConcept C126322002 @default.
• W2113443314 hasConcept C142724271 @default.
• W2113443314 hasConcept C156957248 @default.
• W2113443314 hasConcept C201903717 @default.
• W2113443314 hasConcept C2776102371 @default.
• W2113443314 hasConcept C2776301714 @default.
• W2113443314 hasConcept C2777914695 @default.
• W2113443314 hasConcept C2781069245 @default.
• W2113443314 hasConcept C2908647359 @default.
• W2113443314 hasConcept C61511704 @default.
• W2113443314 hasConcept C71924100 @default.
• W2113443314 hasConcept C99454951 @default.
• W2113443314 hasConceptScore W2113443314C120665830 @default.
• W2113443314 hasConceptScore W2113443314C121332964 @default.
• W2113443314 hasConceptScore W2113443314C126322002 @default.
• W2113443314 hasConceptScore W2113443314C142724271 @default.
• W2113443314 hasConceptScore W2113443314C156957248 @default.
• W2113443314 hasConceptScore W2113443314C201903717 @default.
• W2113443314 hasConceptScore W2113443314C2776102371 @default.
• W2113443314 hasConceptScore W2113443314C2776301714 @default.
• W2113443314 hasConceptScore W2113443314C2777914695 @default.
• W2113443314 hasConceptScore W2113443314C2781069245 @default.
• W2113443314 hasConceptScore W2113443314C2908647359 @default.
• W2113443314 hasConceptScore W2113443314C61511704 @default.
• W2113443314 hasConceptScore W2113443314C71924100 @default.
• W2113443314 hasConceptScore W2113443314C99454951 @default.
• W2113443314 hasIssue "16" @default.
• W2113443314 hasLocation W21134433141 @default.
• W2113443314 hasLocation W21134433142 @default.
• W2113443314 hasOpenAccess W2113443314 @default.
• W2113443314 hasPrimaryLocation W21134433141 @default.
• W2113443314 hasRelatedWork W2042282896 @default.
• W2113443314 hasRelatedWork W2088855007 @default.

• next