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- W2113450022 abstract "Conventional UV phototherapy of psoriasis is one of the safest and most effective treatments for severe psoriasis. Targeted UV phototherapy can also be used to treat localized psoriasis, and this approach offers clearing with fewer treatments as higher doses can be used initially on the psoriasis than can be used on normal skin. A non-laser localized phototherapy system capable of emitting either UVA or a narrow band (290-315nm) of UVB was tested in patients with localized psoriasis. 10 patients with less than 10% affected body surface area were enrolled, and 7 completed the study receiving UVB treatments 2-5 times per week to all lesions. Because this was our first experience with this new device, we used a conservative dose of only 2-4 MED to avoid any potential for blistering. Efficacy was assessed by measuring the thickness, scaling and erythema of target plaques, complemented by photography of the lesions. Generally, excellent improvement (>90% clearing) was seen after between 12 and 25 treatments in all 7 subjects. No blistering or burning occurred; 3 subjects experienced mild, well-tolerated erythema at multiple sessions. Localized, non-laser, narrow band UVB phototherapy appears to be an effective and well-tolerated treatment for psoriasis. The lack of burning or blistering in this study suggests our dosing protocol may be too conservative for patients desiring rapid improvement; further study of more aggressive UV dosing is warranted which may further reduce the number of treatment sessions required." @default.
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- W2113450022 date "2004-03-01" @default.
- W2113450022 modified "2023-09-26" @default.
- W2113450022 title "Non-laser targeted UV treatment for localized psoriasis" @default.
- W2113450022 doi "https://doi.org/10.1016/j.jaad.2003.10.522" @default.
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