FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2113451030> ?p ?o ?g. }

• W2113451030 endingPage "321" @default.
• W2113451030 startingPage "317" @default.
• W2113451030 abstract "The D allele of the ACE I/D gene variant is associated with higher tissue and serum ACE activity. Previously, studies have suggested an association between the D allele with the microvascular complications of diabetes. The aim of this study was to explore the impact of this genotype in relation to clinically manifest peripheral neuropathy (PN) in a cohort of subjects with type 2 diabetes mellitus (type 2 DM). Five hundred and seventy-two Caucasian subjects (230 females, 342 males) with type 2 DM were recruited from the diabetes clinic at University College London Hospitals NHS Trust. Clinically manifest PN was determined from a standardized clinical examination. The ACE I/D genotype distribution was in Hardy–Weinberg equilibrium. In the whole group, no significant association was seen between genotype and PN; however, when stratified by sex, the D allele was associated with PN in females but not in males. The odds ratio (OR) for PN in the D allele carriers compared to those homozygous for the I allele was significantly higher in females [OR 2.93 (1.09–7.63), P=.027] but not in males [OR 1.2 (0.61–2.36), P=.60]. The presence of the D allele is associated with increased risk of peripheral neuropathy in females but not in male subjects with type 2 DM, suggesting a role for the renin–angiotensin system in the development of PN." @default.
• W2113451030 created "2016-06-24" @default.
• W2113451030 creator A5048801731 @default.
• W2113451030 creator A5064235722 @default.
• W2113451030 creator A5065433592 @default.
• W2113451030 creator A5081623247 @default.
• W2113451030 creator A5089717198 @default.
• W2113451030 date "2006-09-01" @default.
• W2113451030 modified "2023-10-16" @default.
• W2113451030 title "A common variant in the ACE gene is associated with peripheral neuropathy in women with type 2 diabetes mellitus" @default.
• W2113451030 cites W1970930841 @default.
• W2113451030 cites W1983442180 @default.
• W2113451030 cites W1985249011 @default.
• W2113451030 cites W1993216454 @default.
• W2113451030 cites W2004164169 @default.
• W2113451030 cites W2015757639 @default.
• W2113451030 cites W2032302835 @default.
• W2113451030 cites W2046806081 @default.
• W2113451030 cites W2051839369 @default.
• W2113451030 cites W2056731899 @default.
• W2113451030 cites W2057586575 @default.
• W2113451030 cites W2068359901 @default.
• W2113451030 cites W2077991668 @default.
• W2113451030 cites W2083698504 @default.
• W2113451030 cites W2086273061 @default.
• W2113451030 cites W2087584879 @default.
• W2113451030 cites W2100021456 @default.
• W2113451030 cites W2128217343 @default.
• W2113451030 cites W2130003438 @default.
• W2113451030 cites W2133150758 @default.
• W2113451030 cites W2153372656 @default.
• W2113451030 cites W2167128829 @default.
• W2113451030 cites W2312400976 @default.
• W2113451030 cites W2417157802 @default.
• W2113451030 cites W2769264260 @default.
• W2113451030 cites W4243861699 @default.
• W2113451030 cites W4245809230 @default.
• W2113451030 doi "https://doi.org/10.1016/j.jdiacomp.2005.07.010" @default.
• W2113451030 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16949519" @default.
• W2113451030 hasPublicationYear "2006" @default.
• W2113451030 type Work @default.
• W2113451030 sameAs 2113451030 @default.
• W2113451030 citedByCount "23" @default.
• W2113451030 countsByYear W21134510302012 @default.
• W2113451030 countsByYear W21134510302013 @default.
• W2113451030 countsByYear W21134510302014 @default.
• W2113451030 countsByYear W21134510302015 @default.
• W2113451030 countsByYear W21134510302016 @default.
• W2113451030 countsByYear W21134510302019 @default.
• W2113451030 countsByYear W21134510302020 @default.
• W2113451030 countsByYear W21134510302023 @default.
• W2113451030 crossrefType "journal-article" @default.
• W2113451030 hasAuthorship W2113451030A5048801731 @default.
• W2113451030 hasAuthorship W2113451030A5064235722 @default.
• W2113451030 hasAuthorship W2113451030A5065433592 @default.
• W2113451030 hasAuthorship W2113451030A5081623247 @default.
• W2113451030 hasAuthorship W2113451030A5089717198 @default.
• W2113451030 hasConcept C104317684 @default.
• W2113451030 hasConcept C126322002 @default.
• W2113451030 hasConcept C134018914 @default.
• W2113451030 hasConcept C135763542 @default.
• W2113451030 hasConcept C156957248 @default.
• W2113451030 hasConcept C180754005 @default.
• W2113451030 hasConcept C2777180221 @default.
• W2113451030 hasConcept C2779901536 @default.
• W2113451030 hasConcept C2910068830 @default.
• W2113451030 hasConcept C54355233 @default.
• W2113451030 hasConcept C555293320 @default.
• W2113451030 hasConcept C71924100 @default.
• W2113451030 hasConcept C72563966 @default.
• W2113451030 hasConcept C86803240 @default.
• W2113451030 hasConcept C90924648 @default.
• W2113451030 hasConceptScore W2113451030C104317684 @default.
• W2113451030 hasConceptScore W2113451030C126322002 @default.
• W2113451030 hasConceptScore W2113451030C134018914 @default.
• W2113451030 hasConceptScore W2113451030C135763542 @default.
• W2113451030 hasConceptScore W2113451030C156957248 @default.
• W2113451030 hasConceptScore W2113451030C180754005 @default.
• W2113451030 hasConceptScore W2113451030C2777180221 @default.
• W2113451030 hasConceptScore W2113451030C2779901536 @default.
• W2113451030 hasConceptScore W2113451030C2910068830 @default.
• W2113451030 hasConceptScore W2113451030C54355233 @default.
• W2113451030 hasConceptScore W2113451030C555293320 @default.
• W2113451030 hasConceptScore W2113451030C71924100 @default.
• W2113451030 hasConceptScore W2113451030C72563966 @default.
• W2113451030 hasConceptScore W2113451030C86803240 @default.
• W2113451030 hasConceptScore W2113451030C90924648 @default.
• W2113451030 hasIssue "5" @default.
• W2113451030 hasLocation W21134510301 @default.
• W2113451030 hasLocation W21134510302 @default.
• W2113451030 hasOpenAccess W2113451030 @default.
• W2113451030 hasPrimaryLocation W21134510301 @default.
• W2113451030 hasRelatedWork W2036624756 @default.
• W2113451030 hasRelatedWork W2068429843 @default.
• W2113451030 hasRelatedWork W2134373856 @default.
• W2113451030 hasRelatedWork W2261335360 @default.
• W2113451030 hasRelatedWork W2347271704 @default.
• W2113451030 hasRelatedWork W2372977423 @default.

• next