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- W2113453791 abstract "During the 1990s major changes occurred in medical practice, clinical guidelines, and national recommendations in the US, paralleling the rise in multiple births. Our objective was to quantify infant mortality risks using national vital statistics data. The study population included all live births of 20 weeks gestation or more from the 1995-2000 US Birth Cohort Linked Birth/Infant Death Data Sets. This included 23,674,816 live births (LBs) and 157,358 infant deaths (IDs). Infant mortality rates (IMRs) were deaths per 1,000 LBs. Adjusted odds ratios (AORs) and 95% confidence intervals were calculated to evaluate the change in risk between 1995-97 and 1998-00 by plurality and compared to the change for singletons. The IMR decreased from 6.03 to 5.68 for singletons, 29.00 to 27.22 for twins, 63.58 to 56.33 for triplets, but increased from 80.54 to 94.01 for quadruplets and quintuplets. The risk of infant mortality decreased significantly overall and for births less than 25 weeks, respectively, for singletons (AOR 0.96, 0.95-0.97 and AOR 0.93, 0.90-0.96), twins (AOR 0.95, 0.93-0.98 and AOR 0.86, 0.80-0.93), and triplets (AOR 0.89, 0.81-0.97 and AOR 0.71, 0.57-0.89). At weeks 25-28, only triplets had a significant decrease (AOR 0.79, 0.66-0.96). At weeks 29-32, only twins had a significant decrease (AOR 0.89, 0.81-0.98). Beyond 32 weeks, only singletons had a decrease (weeks 33-36, AOR 0.89, 0.86-0.92; weeks 37-40, AOR 0.94, 0.92-0.96; and over 40 weeks, AOR 0.93, 0.90-0.97). Compared to singletons, very premature triplets experienced the greatest risk reduction (less than 25 weeks, AOR/AOR 0.76, 0.61-0.96, and 25-28 weeks, AOR/AOR 0.80, 0.66-0.97). The medical advances in the 1990s have improved infant survival rates for nearly all children, particularly those born at less than 28 weeks gestation. Improved survival at increasing earlier gestations, though, has important implications for subsequent physical and mental disabilities." @default.
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- W2113453791 date "2005-12-01" @default.
- W2113453791 modified "2023-10-18" @default.
- W2113453791 title "Plurality and contemporary infant mortality risks" @default.
- W2113453791 doi "https://doi.org/10.1016/j.ajog.2005.10.399" @default.
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