FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2113457051> ?p ?o ?g. }

• W2113457051 abstract "Recent investigations have made considerable progress in the understanding of tissue regeneration driven by mesenchymal stromal cells (MSCs). Data indicate the anatomical location of MSC as residing in the “perivascular” space of blood vessels dispersed across the whole body. This histological localization suggests that MSCs contribute to the formation of new blood vessels in vivo. Indeed, MSCs can release angiogenic factors and protease to facilitate blood vessel formation and in vitro are able to promote/support angiogenesis. However, the direct differentiation of MCSs into endothelial cells is still matter of debate. Most of the conflicting data might arise from the presence of multiple subtypes of cells with heterogeneous morph-functional features within the MSC cultures. According to this scenario, we hypothesize that the presence of the recently described Mesodermal Progenitor Cells (MPCs) within the MSCs cultures is responsible for their variable angiogenic potential. Indeed, MPCs are Nestin-positive CD31-positive cells exhibiting angiogenic potential that differentiate in MSC upon proper stimuli. The ISCT criteria do not account for the presence of MPC within MSC culture generating confusion in the interpretation of MSC angiogenic potential. In conclusion, the discovery of MPC gives new insight in defining MSC ancestors in human bone marrow, and indicates the tunica intima as a further, and previously overlooked, possible additional source of MSC." @default.
• W2113457051 created "2016-06-24" @default.
• W2113457051 creator A5013433148 @default.
• W2113457051 creator A5023355986 @default.
• W2113457051 date "2014-05-20" @default.
• W2113457051 modified "2023-10-14" @default.
• W2113457051 title "Are MSCs angiogenic cells? New insights on human nestin-positive bone marrow-derived multipotent cells" @default.
• W2113457051 cites W1215934946 @default.
• W2113457051 cites W178300840 @default.
• W2113457051 cites W1844685923 @default.
• W2113457051 cites W1875498845 @default.
• W2113457051 cites W1968628080 @default.
• W2113457051 cites W1969443349 @default.
• W2113457051 cites W1970007383 @default.
• W2113457051 cites W1970567133 @default.
• W2113457051 cites W1979155684 @default.
• W2113457051 cites W1986665957 @default.
• W2113457051 cites W1987145582 @default.
• W2113457051 cites W1988830115 @default.
• W2113457051 cites W1992112921 @default.
• W2113457051 cites W1992190771 @default.
• W2113457051 cites W1992434633 @default.
• W2113457051 cites W1993640536 @default.
• W2113457051 cites W1993799809 @default.
• W2113457051 cites W1994851401 @default.
• W2113457051 cites W1997309422 @default.
• W2113457051 cites W2000097208 @default.
• W2113457051 cites W2002320509 @default.
• W2113457051 cites W2006549340 @default.
• W2113457051 cites W2009804171 @default.
• W2113457051 cites W2010118713 @default.
• W2113457051 cites W2012857468 @default.
• W2113457051 cites W2015050458 @default.
• W2113457051 cites W2017950977 @default.
• W2113457051 cites W2018819246 @default.
• W2113457051 cites W2025371271 @default.
• W2113457051 cites W2025838486 @default.
• W2113457051 cites W2027284829 @default.
• W2113457051 cites W2028953197 @default.
• W2113457051 cites W2029599332 @default.
• W2113457051 cites W2030508161 @default.
• W2113457051 cites W2030620101 @default.
• W2113457051 cites W2030920153 @default.
• W2113457051 cites W2035582618 @default.
• W2113457051 cites W2036452348 @default.
• W2113457051 cites W2038961626 @default.
• W2113457051 cites W2041971960 @default.
• W2113457051 cites W2042078137 @default.
• W2113457051 cites W2045456080 @default.
• W2113457051 cites W2046020742 @default.
• W2113457051 cites W2047175022 @default.
• W2113457051 cites W2056510698 @default.
• W2113457051 cites W2061814847 @default.
• W2113457051 cites W2061968656 @default.
• W2113457051 cites W2074188863 @default.
• W2113457051 cites W2074196937 @default.
• W2113457051 cites W2078489918 @default.
• W2113457051 cites W2078501359 @default.
• W2113457051 cites W2079953735 @default.
• W2113457051 cites W2080091183 @default.
• W2113457051 cites W2080551937 @default.
• W2113457051 cites W2082472718 @default.
• W2113457051 cites W2085081174 @default.
• W2113457051 cites W2086793358 @default.
• W2113457051 cites W2087063516 @default.
• W2113457051 cites W2087353148 @default.
• W2113457051 cites W2088762182 @default.
• W2113457051 cites W2091581130 @default.
• W2113457051 cites W2094334540 @default.
• W2113457051 cites W2098400443 @default.
• W2113457051 cites W2106316818 @default.
• W2113457051 cites W2116888866 @default.
• W2113457051 cites W2118622683 @default.
• W2113457051 cites W2118939519 @default.
• W2113457051 cites W2126401208 @default.
• W2113457051 cites W2127300454 @default.
• W2113457051 cites W2127872440 @default.
• W2113457051 cites W2129477690 @default.
• W2113457051 cites W2134827504 @default.
• W2113457051 cites W2140948660 @default.
• W2113457051 cites W2144000430 @default.
• W2113457051 cites W2144224215 @default.
• W2113457051 cites W2144268541 @default.
• W2113457051 cites W2147691664 @default.
• W2113457051 cites W2150817988 @default.
• W2113457051 cites W2155044423 @default.
• W2113457051 cites W2159348812 @default.
• W2113457051 cites W2159999899 @default.
• W2113457051 cites W2165329996 @default.
• W2113457051 cites W2173497140 @default.
• W2113457051 cites W2400103088 @default.
• W2113457051 cites W2468281665 @default.
• W2113457051 cites W2605187236 @default.
• W2113457051 cites W4247628586 @default.
• W2113457051 cites W4292330637 @default.
• W2113457051 cites W1990163773 @default.
• W2113457051 doi "https://doi.org/10.3389/fcell.2014.00020" @default.
• W2113457051 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4207020" @default.
• W2113457051 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25364727" @default.
• W2113457051 hasPublicationYear "2014" @default.

• next