FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2113554225> ?p ?o ?g. }

• W2113554225 endingPage "494" @default.
• W2113554225 startingPage "485" @default.
• W2113554225 abstract "SORs (superoxide reductases) are enzymes involved in bacterial resistance to reactive oxygen species, catalysing the reduction of superoxide anions to hydrogen peroxide. So far three structural classes have been identified. Class I enzymes have two iron-centre-containing domains. Most studies have focused on the catalytic iron site (centre II), yet the role of centre I is poorly understood. The possible roles of this iron site were approached by an integrated study using both classical and fast kinetic measurements, as well as direct electrochemistry. A new heterometallic form of the protein with a zinc-substituted centre I, maintaining the iron active-site centre II, was obtained, resulting in a stable derivative useful for comparison with the native all-iron from. Second-order rate constants for the electron transfer between reduced rubredoxin and the different SOR forms were determined to be 2.8 × 10⁷ M⁻¹ · s⁻¹ and 1.3 × 10⁶ M⁻¹ · s⁻¹ for SORFe(IIII)-Fe(II) and for SORFe(IIII)-Fe(III) forms respectively, and 3.2 × 10⁶ M⁻¹ · s⁻¹ for the SORZn(II)-Fe(III) form. The results obtained seem to indicate that centre I transfers electrons from the putative physiological donor rubredoxin to the catalytic active iron site (intramolecular process). In addition, electrochemical results show that conformational changes are associated with the redox state of centre I, which may enable a faster catalytic response towards superoxide anion. The apparent rate constants calculated for the SOR-mediated electron transfer also support this observation." @default.
• W2113554225 created "2016-06-24" @default.
• W2113554225 creator A5000898785 @default.
• W2113554225 creator A5008724378 @default.
• W2113554225 creator A5021553442 @default.
• W2113554225 creator A5059685097 @default.
• W2113554225 creator A5063411002 @default.
• W2113554225 creator A5072830803 @default.
• W2113554225 creator A5079736054 @default.
• W2113554225 date "2011-08-26" @default.
• W2113554225 modified "2023-10-14" @default.
• W2113554225 title "New spectroscopic and electrochemical insights on a class I superoxide reductase: evidence for an intramolecular electron-transfer pathway" @default.
• W2113554225 cites W1536139694 @default.
• W2113554225 cites W1563233722 @default.
• W2113554225 cites W1564233804 @default.
• W2113554225 cites W1675570769 @default.
• W2113554225 cites W1775749144 @default.
• W2113554225 cites W1967700647 @default.
• W2113554225 cites W1984994687 @default.
• W2113554225 cites W1996366886 @default.
• W2113554225 cites W1997295152 @default.
• W2113554225 cites W2007260948 @default.
• W2113554225 cites W2017508549 @default.
• W2113554225 cites W2018690840 @default.
• W2113554225 cites W2020052486 @default.
• W2113554225 cites W2021326856 @default.
• W2113554225 cites W2021680732 @default.
• W2113554225 cites W2022523144 @default.
• W2113554225 cites W2023721519 @default.
• W2113554225 cites W2023800563 @default.
• W2113554225 cites W2044891596 @default.
• W2113554225 cites W2045226846 @default.
• W2113554225 cites W2049299424 @default.
• W2113554225 cites W2057951054 @default.
• W2113554225 cites W2068156885 @default.
• W2113554225 cites W2069192355 @default.
• W2113554225 cites W2076143128 @default.
• W2113554225 cites W2088161991 @default.
• W2113554225 cites W2089280502 @default.
• W2113554225 cites W2092747452 @default.
• W2113554225 cites W2092861686 @default.
• W2113554225 cites W2105117767 @default.
• W2113554225 cites W2128667586 @default.
• W2113554225 cites W2144814857 @default.
• W2113554225 cites W2147108293 @default.
• W2113554225 cites W2148939303 @default.
• W2113554225 cites W2150179989 @default.
• W2113554225 cites W2152922502 @default.
• W2113554225 cites W2156699734 @default.
• W2113554225 cites W2159079299 @default.
• W2113554225 cites W2963223636 @default.
• W2113554225 cites W4247418485 @default.
• W2113554225 cites W4249659676 @default.
• W2113554225 doi "https://doi.org/10.1042/bj20110836" @default.
• W2113554225 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21682694" @default.
• W2113554225 hasPublicationYear "2011" @default.
• W2113554225 type Work @default.
• W2113554225 sameAs 2113554225 @default.
• W2113554225 citedByCount "16" @default.
• W2113554225 countsByYear W21135542252012 @default.
• W2113554225 countsByYear W21135542252013 @default.
• W2113554225 countsByYear W21135542252016 @default.
• W2113554225 countsByYear W21135542252017 @default.
• W2113554225 countsByYear W21135542252018 @default.
• W2113554225 countsByYear W21135542252019 @default.
• W2113554225 countsByYear W21135542252021 @default.
• W2113554225 countsByYear W21135542252022 @default.
• W2113554225 crossrefType "journal-article" @default.
• W2113554225 hasAuthorship W2113554225A5000898785 @default.
• W2113554225 hasAuthorship W2113554225A5008724378 @default.
• W2113554225 hasAuthorship W2113554225A5021553442 @default.
• W2113554225 hasAuthorship W2113554225A5059685097 @default.
• W2113554225 hasAuthorship W2113554225A5063411002 @default.
• W2113554225 hasAuthorship W2113554225A5072830803 @default.
• W2113554225 hasAuthorship W2113554225A5079736054 @default.
• W2113554225 hasBestOaLocation W21135542252 @default.
• W2113554225 hasConcept C121332964 @default.
• W2113554225 hasConcept C123669783 @default.
• W2113554225 hasConcept C142677202 @default.
• W2113554225 hasConcept C147789679 @default.
• W2113554225 hasConcept C148898269 @default.
• W2113554225 hasConcept C161790260 @default.
• W2113554225 hasConcept C17525397 @default.
• W2113554225 hasConcept C179104552 @default.
• W2113554225 hasConcept C181199279 @default.
• W2113554225 hasConcept C185592680 @default.
• W2113554225 hasConcept C24840226 @default.
• W2113554225 hasConcept C2780795997 @default.
• W2113554225 hasConcept C52859227 @default.
• W2113554225 hasConcept C55493867 @default.
• W2113554225 hasConcept C55904794 @default.
• W2113554225 hasConcept C62520636 @default.
• W2113554225 hasConcept C71240020 @default.
• W2113554225 hasConcept C75079739 @default.
• W2113554225 hasConcept C75473681 @default.
• W2113554225 hasConcept C8010536 @default.
• W2113554225 hasConcept C93391505 @default.
• W2113554225 hasConceptScore W2113554225C121332964 @default.

• next