FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2113644992> ?p ?o ?g. }

• W2113644992 endingPage "528" @default.
• W2113644992 startingPage "507" @default.
• W2113644992 abstract "1. A study was made of functional and structural changes during degeneration of end-plates in the rat diaphragm after phrenic nerve section at two levels. 2. For 8–10 hr after cutting the nerve in the neck, all end-plates retain the ability to transmit impulses. During the following 8–10 hr, an increasing number of end-plates lose this ability so that after a total of about 20 hr, no end-plates can transmit. 3. Transmission failure occurs abruptly at most end-plates. This failure is usually accompanied by cessation of spontaneous miniature end-plate potentials (min.e.p.p.s), though in a few cases min.e.p.p.s persist after junctional transmission has failed. Several degenerating junctions were observed where the frequency of min.e.p.p.s was very low, suggesting an intermediate stage in min.e.p.p. failure. 4. The time of junctional failure depends on the length of the degenerating nerve stump. For each additional centimetre of nerve, failure is delayed about 45 min. 5. Changes in ultrastructure of nerve endings closely parallel those of function. For about 8–12 hr after cutting the nerve, nearly all end-plates appear normal. During the period when transmission is failing, some end-plates are clearly undergoing structural break-down. By the time functional failure is complete, all end-plates appear grossly abnormal. 6. During degeneration, the contents of the axoplasm undergo disruption and the nerve terminal breaks up into small fragments. In contrast, the Schwann cell appears to become very active and its processes extend into the synaptic cleft to surround fragments of the nerve terminal. Ultimately, the Schwann cell completely replaces the axon at the end-plate. 7. Increasing the length of the peripheral nerve stump delays the onset of structural break-down. Disruption of end-plates near the site of nerve entry into the muscle occurs before those farther away. 8. It is suggested that end-plate degeneration is triggered by a signal which passes from the site of injury to the nerve terminal. The duration of the period after transection when end-plates appear to be normal would then reflect the time required for this signal to travel the length of the isolated nerve stump." @default.
• W2113644992 created "2016-06-24" @default.
• W2113644992 creator A5035781296 @default.
• W2113644992 creator A5050435295 @default.
• W2113644992 date "1970-04-01" @default.
• W2113644992 modified "2023-10-11" @default.
• W2113644992 title "On the degeneration of rat neuromuscular junctions after nerve section" @default.
• W2113644992 cites W1618384257 @default.
• W2113644992 cites W1622099522 @default.
• W2113644992 cites W180971502 @default.
• W2113644992 cites W1967715375 @default.
• W2113644992 cites W1968225522 @default.
• W2113644992 cites W1980961330 @default.
• W2113644992 cites W1981527965 @default.
• W2113644992 cites W1994002190 @default.
• W2113644992 cites W1996647513 @default.
• W2113644992 cites W2000647233 @default.
• W2113644992 cites W2006036013 @default.
• W2113644992 cites W2007864835 @default.
• W2113644992 cites W2024400136 @default.
• W2113644992 cites W2028891320 @default.
• W2113644992 cites W2038346963 @default.
• W2113644992 cites W2043742761 @default.
• W2113644992 cites W2046317880 @default.
• W2113644992 cites W2060604409 @default.
• W2113644992 cites W2062070852 @default.
• W2113644992 cites W2069028571 @default.
• W2113644992 cites W2077885742 @default.
• W2113644992 cites W2102492718 @default.
• W2113644992 cites W2154619058 @default.
• W2113644992 cites W2170755191 @default.
• W2113644992 cites W2284497297 @default.
• W2113644992 cites W2287605586 @default.
• W2113644992 cites W2398180298 @default.
• W2113644992 cites W2412610319 @default.
• W2113644992 cites W2413338887 @default.
• W2113644992 cites W2413353058 @default.
• W2113644992 cites W2414452718 @default.
• W2113644992 cites W2414773323 @default.
• W2113644992 cites W2417422631 @default.
• W2113644992 cites W252400416 @default.
• W2113644992 doi "https://doi.org/10.1113/jphysiol.1970.sp009076" @default.
• W2113644992 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1348721" @default.
• W2113644992 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5499034" @default.
• W2113644992 hasPublicationYear "1970" @default.
• W2113644992 type Work @default.
• W2113644992 sameAs 2113644992 @default.
• W2113644992 citedByCount "396" @default.
• W2113644992 countsByYear W21136449922012 @default.
• W2113644992 countsByYear W21136449922013 @default.
• W2113644992 countsByYear W21136449922014 @default.
• W2113644992 countsByYear W21136449922015 @default.
• W2113644992 countsByYear W21136449922016 @default.
• W2113644992 countsByYear W21136449922017 @default.
• W2113644992 countsByYear W21136449922018 @default.
• W2113644992 countsByYear W21136449922019 @default.
• W2113644992 countsByYear W21136449922020 @default.
• W2113644992 countsByYear W21136449922021 @default.
• W2113644992 countsByYear W21136449922022 @default.
• W2113644992 crossrefType "journal-article" @default.
• W2113644992 hasAuthorship W2113644992A5035781296 @default.
• W2113644992 hasAuthorship W2113644992A5050435295 @default.
• W2113644992 hasBestOaLocation W21136449922 @default.
• W2113644992 hasConcept C105702510 @default.
• W2113644992 hasConcept C126322002 @default.
• W2113644992 hasConcept C142724271 @default.
• W2113644992 hasConcept C169760540 @default.
• W2113644992 hasConcept C185592680 @default.
• W2113644992 hasConcept C194575858 @default.
• W2113644992 hasConcept C2777099253 @default.
• W2113644992 hasConcept C2777240379 @default.
• W2113644992 hasConcept C2779354088 @default.
• W2113644992 hasConcept C2779530196 @default.
• W2113644992 hasConcept C2909516373 @default.
• W2113644992 hasConcept C3020341438 @default.
• W2113644992 hasConcept C534529494 @default.
• W2113644992 hasConcept C71924100 @default.
• W2113644992 hasConcept C86803240 @default.
• W2113644992 hasConceptScore W2113644992C105702510 @default.
• W2113644992 hasConceptScore W2113644992C126322002 @default.
• W2113644992 hasConceptScore W2113644992C142724271 @default.
• W2113644992 hasConceptScore W2113644992C169760540 @default.
• W2113644992 hasConceptScore W2113644992C185592680 @default.
• W2113644992 hasConceptScore W2113644992C194575858 @default.
• W2113644992 hasConceptScore W2113644992C2777099253 @default.
• W2113644992 hasConceptScore W2113644992C2777240379 @default.
• W2113644992 hasConceptScore W2113644992C2779354088 @default.
• W2113644992 hasConceptScore W2113644992C2779530196 @default.
• W2113644992 hasConceptScore W2113644992C2909516373 @default.
• W2113644992 hasConceptScore W2113644992C3020341438 @default.
• W2113644992 hasConceptScore W2113644992C534529494 @default.
• W2113644992 hasConceptScore W2113644992C71924100 @default.
• W2113644992 hasConceptScore W2113644992C86803240 @default.
• W2113644992 hasIssue "2" @default.
• W2113644992 hasLocation W21136449921 @default.
• W2113644992 hasLocation W21136449922 @default.
• W2113644992 hasLocation W21136449923 @default.
• W2113644992 hasOpenAccess W2113644992 @default.

• next