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• W2113681631 abstract "This paper presents a novel application of magnetic particles for biosensing, called label-acquired magnetorotation (LAM). This method is based on a combination of the traditional sandwich assay format with the asynchronous magnetic bead rotation (AMBR) method. In label-acquired magnetorotation, an analyte facilitates the binding of a magnetic label bead to a nonmagnetic solid phase sphere, forming a sandwich complex. The sandwich complex is then placed in a rotating magnetic field, where the rotational frequency of the sandwich complex is a function of the amount of analyte attached to the surface of the sphere. Here, we use streptavidin-coated beads and biotin-coated particles as analyte mimics, to be replaced by proteins and other biological targets in future work. We show this sensing method to have a dynamic range of two orders of magnitude." @default.
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• W2113681631 date "2011-02-01" @default.
• W2113681631 modified "2023-09-28" @default.
• W2113681631 title "Label-acquired magnetorotation for biosensing: An asynchronous rotation assay" @default.
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• W2113681631 doi "https://doi.org/10.1016/j.jmmm.2010.09.014" @default.
• W2113681631 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3480196" @default.
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