FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2113692023> ?p ?o ?g. }

• W2113692023 abstract "Autoimmune hepatitis (AIH) has been reported to show considerable geographical variation in frequency and clinical manifestations. It is considered a rare cause of liver disease in India. The present study was undertaken to determine the incidence, clinical, biochemical and histological profile of AIH in this part of the world.Patients presenting with acute or chronic liver disease between January 1999 and June 2002 were evaluated prospectively. AIH was diagnosed using the international autoimmune hepatitis group criteria. Workup included clinical, biochemical, USG, viral markers, UGI endoscopy, AI markers (ANA, SMA, Anti-LKM, AMA, RF, p-ANCA) using indirect immunofluorescence and liver biopsy if possible.Forty-one of 2401 (1.70%) patients were diagnosed to have autoimmune liver disease. Out of these, 38 had autoimmune hepatitis and the rest 3 had primary biliary cirrhosis. The mean age of the patients of autoimmune hepatitis was 36.2 (15.9) years, 34 (89.4%) were females, and the duration of symptoms was 20.3 (20.5) months. Nineteen (50%) of them presented with chronic hepatitis, 13 (34.2%) as cirrhosis, 5 (13.1%) with acute hepatitis and 1 (2.6%) with cholestatic hepatitis. The presentations were jaundice in 21 (55.2%), pedal edema and hepatomegaly in 17 (44.7%), splenomegaly in 13 (34.2%), encephalopathy, abdominal pain in 9 (23.6%) and fever in 8 (21%). Twelve had esophageal varices and 3 had bled. Biochemical parameters were ALT 187 (360) U/L, AST 157 (193) U/L, ALP 246 (254) U/L, globulin 4.1 (1.6) g/dL, albumin 2.8 (0.9) g/dL, bilirubin 5.2 (7.4) mg/dL, prothrombin time 17 (7) sec and ESR 47 (17) sec. The autoimmune markers were SMA (24), ANA (15), both SMA and ANA (4), AMA (1), rheumatoid factor (2), pANCA (1), and Anti-LKM in none. Thirty (79%) patients had definite AIH and eight (21%) had probable AI hepatitis. Associated autoimmune diseases was seen in 15/38 (39.4%), diabetes 4, hypothyroidism 3, vitiligo 2, thrombocytopenia 2, rheumatoid arthritis 2, Sjogren's syndrome 1 and autoimmune polyglandular syndrome III in 1. Viral markers were positive in two patients, one presenting as acute hepatitis and HEV-IgM positive and another anti-HCV positive.In India, autoimmune hepatitis is uncommon and usually presents with chronic hepatitis or cirrhosis, acute hepatitis being less common. Age at presentation was earlier but clinical parameters and associated autoimmune diseases were similar to that reported from the west. Primary biliary cirrhosis is rare. Type II AIH was not observed." @default.
• W2113692023 created "2016-06-24" @default.
• W2113692023 creator A5029322376 @default.
• W2113692023 creator A5036064125 @default.
• W2113692023 creator A5045441660 @default.
• W2113692023 creator A5053031531 @default.
• W2113692023 date "2005-08-15" @default.
• W2113692023 modified "2023-10-14" @default.
• W2113692023 title "Autoimmune hepatitis in India: profile of an uncommon disease" @default.
• W2113692023 cites W111028579 @default.
• W2113692023 cites W1970955791 @default.
• W2113692023 cites W1985124259 @default.
• W2113692023 cites W1998891055 @default.
• W2113692023 cites W2004003332 @default.
• W2113692023 cites W2006381953 @default.
• W2113692023 cites W2016193783 @default.
• W2113692023 cites W2050642916 @default.
• W2113692023 cites W2051833434 @default.
• W2113692023 cites W2085337624 @default.
• W2113692023 cites W2132675308 @default.
• W2113692023 cites W2159954692 @default.
• W2113692023 cites W2170705556 @default.
• W2113692023 cites W2316240564 @default.
• W2113692023 cites W2394869810 @default.
• W2113692023 cites W2412096530 @default.
• W2113692023 doi "https://doi.org/10.1186/1471-230x-5-27" @default.
• W2113692023 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1236920" @default.
• W2113692023 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16098234" @default.
• W2113692023 hasPublicationYear "2005" @default.
• W2113692023 type Work @default.
• W2113692023 sameAs 2113692023 @default.
• W2113692023 citedByCount "60" @default.
• W2113692023 countsByYear W21136920232012 @default.
• W2113692023 countsByYear W21136920232013 @default.
• W2113692023 countsByYear W21136920232014 @default.
• W2113692023 countsByYear W21136920232015 @default.
• W2113692023 countsByYear W21136920232016 @default.
• W2113692023 countsByYear W21136920232017 @default.
• W2113692023 countsByYear W21136920232018 @default.
• W2113692023 countsByYear W21136920232019 @default.
• W2113692023 countsByYear W21136920232020 @default.
• W2113692023 countsByYear W21136920232022 @default.
• W2113692023 countsByYear W21136920232023 @default.
• W2113692023 crossrefType "journal-article" @default.
• W2113692023 hasAuthorship W2113692023A5029322376 @default.
• W2113692023 hasAuthorship W2113692023A5036064125 @default.
• W2113692023 hasAuthorship W2113692023A5045441660 @default.
• W2113692023 hasAuthorship W2113692023A5053031531 @default.
• W2113692023 hasBestOaLocation W21136920231 @default.
• W2113692023 hasConcept C126322002 @default.
• W2113692023 hasConcept C2775934546 @default.
• W2113692023 hasConcept C2776029263 @default.
• W2113692023 hasConcept C2777072776 @default.
• W2113692023 hasConcept C2777075537 @default.
• W2113692023 hasConcept C2777203481 @default.
• W2113692023 hasConcept C2777214474 @default.
• W2113692023 hasConcept C2777766500 @default.
• W2113692023 hasConcept C2779102576 @default.
• W2113692023 hasConcept C41260117 @default.
• W2113692023 hasConcept C71924100 @default.
• W2113692023 hasConcept C90924648 @default.
• W2113692023 hasConceptScore W2113692023C126322002 @default.
• W2113692023 hasConceptScore W2113692023C2775934546 @default.
• W2113692023 hasConceptScore W2113692023C2776029263 @default.
• W2113692023 hasConceptScore W2113692023C2777072776 @default.
• W2113692023 hasConceptScore W2113692023C2777075537 @default.
• W2113692023 hasConceptScore W2113692023C2777203481 @default.
• W2113692023 hasConceptScore W2113692023C2777214474 @default.
• W2113692023 hasConceptScore W2113692023C2777766500 @default.
• W2113692023 hasConceptScore W2113692023C2779102576 @default.
• W2113692023 hasConceptScore W2113692023C41260117 @default.
• W2113692023 hasConceptScore W2113692023C71924100 @default.
• W2113692023 hasConceptScore W2113692023C90924648 @default.
• W2113692023 hasIssue "1" @default.
• W2113692023 hasLocation W21136920231 @default.
• W2113692023 hasLocation W21136920232 @default.
• W2113692023 hasLocation W21136920233 @default.
• W2113692023 hasLocation W21136920234 @default.
• W2113692023 hasOpenAccess W2113692023 @default.
• W2113692023 hasPrimaryLocation W21136920231 @default.
• W2113692023 hasRelatedWork W1944240859 @default.
• W2113692023 hasRelatedWork W1980748566 @default.
• W2113692023 hasRelatedWork W2045185220 @default.
• W2113692023 hasRelatedWork W2077232892 @default.
• W2113692023 hasRelatedWork W2083138014 @default.
• W2113692023 hasRelatedWork W2083834978 @default.
• W2113692023 hasRelatedWork W2087058456 @default.
• W2113692023 hasRelatedWork W2350922131 @default.
• W2113692023 hasRelatedWork W2370683147 @default.
• W2113692023 hasRelatedWork W3172481002 @default.
• W2113692023 hasVolume "5" @default.
• W2113692023 isParatext "false" @default.
• W2113692023 isRetracted "false" @default.
• W2113692023 magId "2113692023" @default.
• W2113692023 workType "article" @default.