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- W2113703309 abstract "Fourth-instar larvae of Aedes aegypti synthesize two types of hexamerins, Hexamerin-1 (AaHex-1) and Hexamerin-2 (AaHex-2), whose subunits are distinguished by different methionine and aromatic amino acid contents. In early female pupae only the methionine-rich AaHex-1γ subunit accumulates to two-fold higher levels than in males. To investigate the relationship between hexamerin structure and the roles of Hex-1 and Hex-2 during mosquito development and reproduction, we have cloned and sequenced cDNAs encoding the AaHex-2α, -2β and AaHex-1γ subunits. Comparison with other insect hexamerins revealed that the Aedes Hex-1 and Hex-2 proteins belong, respectively, to the two hexamerin subfamilies previously defined for brachyceran Diptera. Probes specific for the Hex-2α and Hex-1γ transcripts showed that expression of both genes follows the same developmental timetable. However, greater Hex-1γ mRNA accumulation may contribute to the higher levels of Hex-1γ protein in early female pupae." @default.
- W2113703309 created "2016-06-24" @default.
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- W2113703309 date "1999-02-01" @default.
- W2113703309 modified "2023-10-17" @default.
- W2113703309 title "Molecular cloning and expression of two hexamerin cDNAs from the mosquito, Aedes aegypti" @default.
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- W2113703309 doi "https://doi.org/10.1046/j.1365-2583.1999.810055.x" @default.
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