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- W2113720004 abstract "ABSTRACT The present study demonstrates the efficacy of anidulafungin on mature Candida albicans biofilms in vivo . One hundred fifty-seven catheter fragments challenged with C. albicans were implanted subcutaneously in rats. After formation of biofilms, rats were treated with daily intraperitoneal injections of anidulafungin for 7 days. Catheters retrieved from treated animals showed reduced cell numbers compared to those retrieved from untreated and fluconazole-treated animals. Systemic administration of anidulafungin is promising for the treatment of mature C. albicans biofilms." @default.
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- W2113720004 date "2010-10-01" @default.
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- W2113720004 title "<i>In Vivo</i> Efficacy of Anidulafungin against Mature <i>Candida albicans</i> Biofilms in a Novel Rat Model of Catheter-Associated Candidiasis" @default.
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- W2113720004 doi "https://doi.org/10.1128/aac.00697-10" @default.
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