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• W2113776805 abstract "Recent clinical and biometrical studies strongly support the classical findings of an inherited component in schizophrenia, and are now being used to try to define the phenotype. Linkage studies have generated conflicting data, possibly due to the necessary assumptions that have to be made regarding phenotype definition, the model of inheritance and the degree of penetrance of the supposed gene. Alternative approaches, such as sib-pair analysis overcome some but not all these difficulties, and cytogenetic abnormalities may yet outline regions of the genome for closer scrutiny. The relationship between genes involved in the development of the brain, and the dysplastic features suggested by neuropathologica and neuroimaging studies of the brains of schizophrenics, is one of the most potentially productive areas for research. Elucidation of the nature of the genetic component will help to clarify whether it acts independently or synergistically with the foetal environment in producing the neurodevelopmental ..." @default.
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• W2113776805 date "1989-01-01" @default.
• W2113776805 modified "2023-09-24" @default.
• W2113776805 title "Schizophrenia Research: attempting to integrate genetics, neurodevelopment and nosology" @default.
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• W2113776805 doi "https://doi.org/10.3109/09540268909089421" @default.
• W2113776805 hasPublicationYear "1989" @default.
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