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- W2113780413 abstract "Sampling substrate specificity: An enlarged coenzyme A analogue, acetyl-3′′-O-benzyl-CoA, has been synthesised from D-pantethine by using the enzymes DPCK and PPAT. The analogue was evaluated to determine if it is a selective cosubstrate for the histone acetyltransferase PCAF mutant Q581A so as to allow it to be used to identify the non-histone substrates of this enzyme. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article." @default.
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- W2113780413 date "2010-09-06" @default.
- W2113780413 modified "2023-10-16" @default.
- W2113780413 title "Complementary PCAF-Coenzyme A Mutagenesis: Chemoenzymatic Synthesis of a Novel Enlarged Coenzyme A Analogue and Evaluation of Its Biological Activity" @default.
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- W2113780413 doi "https://doi.org/10.1002/cbic.201000286" @default.
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