FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2113804893> ?p ?o ?g. }

• W2113804893 endingPage "514" @default.
• W2113804893 startingPage "507" @default.
• W2113804893 abstract "In Brief Objective: To evaluate the contribution of the liver to total circulatory reticuloendothelial system (RES) phagocytosis capacity in patients undergoing liver resection and to compare it with values in end-stage chronic liver disease. Summary Background Data: The mechanism whereby major liver resection is associated with a high incidence of infection is unknown. Significant impairment of RES phagocytosis has been described in liver failure, rendering such patients susceptible to infection; and we hypothesized that similar impairment might occur following major liver resection. Methods: A prospective study was conducted in which 99mTc-albumin microspheres blood clearance served as a parameter for RES phagocytosis and was studied together with indocyanine green blood clearance, actual liver volume measured by three-dimensional image analysis, and a clinical score of hepatic dysfunction in 17 patients undergoing liver resection and in 8 patients with end-stage chronic liver disease assessed for liver transplantation. Results: When expressed relative to volume unit of residual liver, microspheres clearance increased significantly in the immediate postoperative period (day 1) following major (0.009% versus 0.022% min−1mL−1, P < 0.001), but not minor liver resection. In contrast, the absolute rate of microsphere clearance decreased following major resection (15% min−1 versus 10% min−1, P < 0.001) and was comparable with the rate observed in end-stage chronic liver disease (9% min−1). This decrease in circulatory microspheres clearance after resection paralleled a decrease in indocyanine green clearance (R2 = 0.511, P = 0.006), and there was a trend for those with moderate liver dysfunction to have lower microspheres clearance rates (P = 0.068). Conclusion: Preservation of a minimum volume of functioning liver is a prerequisite for adequate RES phagocytosis capacity, and failure of this system may predispose patients undergoing major liver resection to infection as observed in clinical studies. This study investigated whether the ability of the reticuloendothelial system to clear 99Tc-albumin microspheres from the circulation was compromised by major liver resection. Reticuloendothelial cell system clearance was increased per unit volume of residual liver; however, total clearance was significantly reduced and was comparable with that of patients with end-stage chronic liver disease." @default.
• W2113804893 created "2016-06-24" @default.
• W2113804893 creator A5004534829 @default.
• W2113804893 creator A5017006323 @default.
• W2113804893 creator A5045833996 @default.
• W2113804893 creator A5061641578 @default.
• W2113804893 creator A5065648317 @default.
• W2113804893 creator A5067608267 @default.
• W2113804893 creator A5068413563 @default.
• W2113804893 creator A5086225597 @default.
• W2113804893 date "2006-04-01" @default.
• W2113804893 modified "2023-09-30" @default.
• W2113804893 title "The Adaptive Response of the Reticuloendothelial System to Major Liver Resection in Humans" @default.
• W2113804893 cites W1946566829 @default.
• W2113804893 cites W1963542213 @default.
• W2113804893 cites W1969810672 @default.
• W2113804893 cites W1979911089 @default.
• W2113804893 cites W1980369159 @default.
• W2113804893 cites W1982010030 @default.
• W2113804893 cites W1985807442 @default.
• W2113804893 cites W1986190356 @default.
• W2113804893 cites W1988005482 @default.
• W2113804893 cites W1991464867 @default.
• W2113804893 cites W2003451011 @default.
• W2113804893 cites W2016176612 @default.
• W2113804893 cites W2016608510 @default.
• W2113804893 cites W2025738183 @default.
• W2113804893 cites W2028067695 @default.
• W2113804893 cites W2029612554 @default.
• W2113804893 cites W2040187497 @default.
• W2113804893 cites W2044120253 @default.
• W2113804893 cites W2049505035 @default.
• W2113804893 cites W2050851266 @default.
• W2113804893 cites W2053909925 @default.
• W2113804893 cites W2057240098 @default.
• W2113804893 cites W2060123467 @default.
• W2113804893 cites W2078839914 @default.
• W2113804893 cites W2083592521 @default.
• W2113804893 cites W2090667112 @default.
• W2113804893 cites W2096286937 @default.
• W2113804893 cites W2103011157 @default.
• W2113804893 cites W2103036266 @default.
• W2113804893 cites W2126019624 @default.
• W2113804893 cites W2176377563 @default.
• W2113804893 cites W4236842068 @default.
• W2113804893 cites W4238798302 @default.
• W2113804893 doi "https://doi.org/10.1097/01.sla.0000205826.62911.a7" @default.
• W2113804893 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1448969" @default.
• W2113804893 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16552202" @default.
• W2113804893 hasPublicationYear "2006" @default.
• W2113804893 type Work @default.
• W2113804893 sameAs 2113804893 @default.
• W2113804893 citedByCount "52" @default.
• W2113804893 countsByYear W21138048932012 @default.
• W2113804893 countsByYear W21138048932013 @default.
• W2113804893 countsByYear W21138048932014 @default.
• W2113804893 countsByYear W21138048932015 @default.
• W2113804893 countsByYear W21138048932016 @default.
• W2113804893 countsByYear W21138048932017 @default.
• W2113804893 countsByYear W21138048932018 @default.
• W2113804893 countsByYear W21138048932019 @default.
• W2113804893 countsByYear W21138048932021 @default.
• W2113804893 countsByYear W21138048932022 @default.
• W2113804893 countsByYear W21138048932023 @default.
• W2113804893 crossrefType "journal-article" @default.
• W2113804893 hasAuthorship W2113804893A5004534829 @default.
• W2113804893 hasAuthorship W2113804893A5017006323 @default.
• W2113804893 hasAuthorship W2113804893A5045833996 @default.
• W2113804893 hasAuthorship W2113804893A5061641578 @default.
• W2113804893 hasAuthorship W2113804893A5065648317 @default.
• W2113804893 hasAuthorship W2113804893A5067608267 @default.
• W2113804893 hasAuthorship W2113804893A5068413563 @default.
• W2113804893 hasAuthorship W2113804893A5086225597 @default.
• W2113804893 hasBestOaLocation W21138048932 @default.
• W2113804893 hasConcept C126322002 @default.
• W2113804893 hasConcept C126894567 @default.
• W2113804893 hasConcept C141071460 @default.
• W2113804893 hasConcept C142724271 @default.
• W2113804893 hasConcept C19702531 @default.
• W2113804893 hasConcept C2776125364 @default.
• W2113804893 hasConcept C2777075537 @default.
• W2113804893 hasConcept C2777214474 @default.
• W2113804893 hasConcept C2779102576 @default.
• W2113804893 hasConcept C2779609443 @default.
• W2113804893 hasConcept C2781065829 @default.
• W2113804893 hasConcept C2911091166 @default.
• W2113804893 hasConcept C71924100 @default.
• W2113804893 hasConcept C90924648 @default.
• W2113804893 hasConceptScore W2113804893C126322002 @default.
• W2113804893 hasConceptScore W2113804893C126894567 @default.
• W2113804893 hasConceptScore W2113804893C141071460 @default.
• W2113804893 hasConceptScore W2113804893C142724271 @default.
• W2113804893 hasConceptScore W2113804893C19702531 @default.
• W2113804893 hasConceptScore W2113804893C2776125364 @default.
• W2113804893 hasConceptScore W2113804893C2777075537 @default.
• W2113804893 hasConceptScore W2113804893C2777214474 @default.
• W2113804893 hasConceptScore W2113804893C2779102576 @default.
• W2113804893 hasConceptScore W2113804893C2779609443 @default.

• next