FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2113807798> ?p ?o ?g. }

• W2113807798 endingPage "424" @default.
• W2113807798 startingPage "415" @default.
• W2113807798 abstract "To establish the feasibility of magnetoliposome tumor targeting with an extracorporeal magnet.Animal experiments were performed in compliance with Institut National de la Santé Et de la Recherche Médicale animal protection guidelines and were approved by local government authorities. Magnetophoresis was used to measure the velocity of magnetoliposomes constituted of polyethylene glycol-lipids and anionic maghemite nanocrystals in a calibrated magnetic field in vitro. For in vivo studies, 38 male Swiss nude mice bearing a PC3 human prostate carcinoma tumor in each flank received an intravenous injection of magnetoliposomes (n = 27), saline (n = 9), or nonencapsulated superparamagnetic particles (n = 2) after a small magnet with a magnetic field of 0.3 T and a field gradient of 11 T/m was fixed to the skin above one tumor. The animals were examined at magnetic resonance (MR) imaging with eight different sequences, iron doses (13 mice), and magnet-application durations (12 mice). Their excised tumors were then stained with Perls Prussian blue and hematoxylin-eosin and were examined histologically. With use of the paired Student t test, signal intensity, tumor surface enhancement, and number of stained cells were compared between the control and magnet-exposed tumors to determine significant differences (P </= .01).The mean magnetoliposome velocity ranged from 10 to 40 mum/sec when the magnetic field equaled 0.13 T and the field gradient equaled 25 T/m. At T1-weighted three-dimensional spoiled gradient-echo MR imaging in vivo, the tumor exposed to the magnet showed strong negative enhancement, -52%, compared with the -7% enhancement of the other tumor. Maximal enhancement occurred after 3 hours of magnet application. After 24 hours of magnet application, intracapillary iron particle accumulation was observed in the targeted tumors only.Magnetic targeting of sterically stabilized magnetoliposomes after they are intravenously injected is feasible in vivo." @default.
• W2113807798 created "2016-06-24" @default.
• W2113807798 creator A5004877313 @default.
• W2113807798 creator A5004991950 @default.
• W2113807798 creator A5030301155 @default.
• W2113807798 creator A5034456156 @default.
• W2113807798 creator A5048556415 @default.
• W2113807798 creator A5048859922 @default.
• W2113807798 creator A5055178926 @default.
• W2113807798 creator A5074173045 @default.
• W2113807798 date "2006-05-01" @default.
• W2113807798 modified "2023-10-12" @default.
• W2113807798 title "Magnetic Targeting of Magnetoliposomes to Solid Tumors with MR Imaging Monitoring in Mice: Feasibility" @default.
• W2113807798 cites W1534320818 @default.
• W2113807798 cites W1583485697 @default.
• W2113807798 cites W1593844282 @default.
• W2113807798 cites W1964095798 @default.
• W2113807798 cites W1972767425 @default.
• W2113807798 cites W1973774460 @default.
• W2113807798 cites W1980145883 @default.
• W2113807798 cites W1981350889 @default.
• W2113807798 cites W1981777363 @default.
• W2113807798 cites W1982470760 @default.
• W2113807798 cites W1992105143 @default.
• W2113807798 cites W1993706573 @default.
• W2113807798 cites W1997581080 @default.
• W2113807798 cites W2004695587 @default.
• W2113807798 cites W2009344870 @default.
• W2113807798 cites W2014721045 @default.
• W2113807798 cites W2015371492 @default.
• W2113807798 cites W2015682585 @default.
• W2113807798 cites W2018693859 @default.
• W2113807798 cites W2021377736 @default.
• W2113807798 cites W2025798968 @default.
• W2113807798 cites W2029501392 @default.
• W2113807798 cites W2037458039 @default.
• W2113807798 cites W2041941824 @default.
• W2113807798 cites W2045570929 @default.
• W2113807798 cites W2049774596 @default.
• W2113807798 cites W2057396158 @default.
• W2113807798 cites W2061672022 @default.
• W2113807798 cites W2066499693 @default.
• W2113807798 cites W2070342688 @default.
• W2113807798 cites W2071958270 @default.
• W2113807798 cites W2073960983 @default.
• W2113807798 cites W2082717426 @default.
• W2113807798 cites W2082931862 @default.
• W2113807798 cites W2094692367 @default.
• W2113807798 cites W2104631267 @default.
• W2113807798 cites W2106558810 @default.
• W2113807798 cites W2113180620 @default.
• W2113807798 cites W2118878458 @default.
• W2113807798 cites W2153856380 @default.
• W2113807798 cites W2163560737 @default.
• W2113807798 cites W2169532237 @default.
• W2113807798 cites W4238556044 @default.
• W2113807798 doi "https://doi.org/10.1148/radiol.2392042110" @default.
• W2113807798 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16549622" @default.
• W2113807798 hasPublicationYear "2006" @default.
• W2113807798 type Work @default.
• W2113807798 sameAs 2113807798 @default.
• W2113807798 citedByCount "134" @default.
• W2113807798 countsByYear W21138077982012 @default.
• W2113807798 countsByYear W21138077982013 @default.
• W2113807798 countsByYear W21138077982014 @default.
• W2113807798 countsByYear W21138077982015 @default.
• W2113807798 countsByYear W21138077982016 @default.
• W2113807798 countsByYear W21138077982017 @default.
• W2113807798 countsByYear W21138077982018 @default.
• W2113807798 countsByYear W21138077982019 @default.
• W2113807798 countsByYear W21138077982020 @default.
• W2113807798 countsByYear W21138077982021 @default.
• W2113807798 countsByYear W21138077982022 @default.
• W2113807798 countsByYear W21138077982023 @default.
• W2113807798 crossrefType "journal-article" @default.
• W2113807798 hasAuthorship W2113807798A5004877313 @default.
• W2113807798 hasAuthorship W2113807798A5004991950 @default.
• W2113807798 hasAuthorship W2113807798A5030301155 @default.
• W2113807798 hasAuthorship W2113807798A5034456156 @default.
• W2113807798 hasAuthorship W2113807798A5048556415 @default.
• W2113807798 hasAuthorship W2113807798A5048859922 @default.
• W2113807798 hasAuthorship W2113807798A5055178926 @default.
• W2113807798 hasAuthorship W2113807798A5074173045 @default.
• W2113807798 hasConcept C121332964 @default.
• W2113807798 hasConcept C125473707 @default.
• W2113807798 hasConcept C126838900 @default.
• W2113807798 hasConcept C136229726 @default.
• W2113807798 hasConcept C142724271 @default.
• W2113807798 hasConcept C143409427 @default.
• W2113807798 hasConcept C147789679 @default.
• W2113807798 hasConcept C150903083 @default.
• W2113807798 hasConcept C16389437 @default.
• W2113807798 hasConcept C17525397 @default.
• W2113807798 hasConcept C185592680 @default.
• W2113807798 hasConcept C207001950 @default.
• W2113807798 hasConcept C2779064266 @default.
• W2113807798 hasConcept C2989005 @default.
• W2113807798 hasConcept C46141821 @default.

• next