FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2113815624> ?p ?o ?g. }

• W2113815624 endingPage "150" @default.
• W2113815624 startingPage "143" @default.
• W2113815624 abstract "BACKGROUND AND PURPOSE: Analysis of specific features in the brain of patients with holoprosencephaly (HPE) may clarify normal and abnormal brain development and help predict outcomes for specific children. We assessed sulcal and gyral patterns of cerebral cortex in patients with HPE and developed a method of grading brain development. METHODS: Neuroimaging studies (75 MR imaging, 21 CT) of 96 patients with HPE were retrospectively reviewed, with specific attention paid to the cerebral cortex. Thickness of cortex, width of gyri, and depth of sulci were assessed subjectively and by measurement. The angle between lines drawn tangential to the sylvian fissures (“sylvian angle”) was measured in each patient with HPE and in 20 control patients. RESULTS: Thickness of cortex was normal in all 96 patients. Gyral shape and width and sulcal depth were normal in 80 patients. Twelve patients, all with very severe HPE and microcephaly, had reduced sulcal depth, diffusely in eight and limited to the anteromedial cortex in four with lobar HPE. Four patients had subcortical heterotopia, located anterior to the interhemispheric fissure, associated with shallow sulci in the overlying cortex. Sylvian fissures were displaced further anteriorly and medially as HPE became more severe, until, in the most severe cases, no sylvian fissures could be identified. Sylvian angle measurements corresponded closely with severity of HPE, being largest in the most severe and smallest in the least severe cases. All patients with HPE had sylvian angles significantly larger than the mean of 15° measured in the control patients. CONCLUSION: The only true malformations of cortical development were subcortical heterotopia. However, diffuse and focal abnormal sulci were observed. We propose our sylvian angle measurement of extent of frontal lobe development as an objective means of quantifying the severity of HPE." @default.
• W2113815624 created "2016-06-24" @default.
• W2113815624 creator A5013333842 @default.
• W2113815624 creator A5018703759 @default.
• W2113815624 creator A5038583289 @default.
• W2113815624 creator A5076301593 @default.
• W2113815624 creator A5076632414 @default.
• W2113815624 date "2002-01-01" @default.
• W2113815624 modified "2023-09-24" @default.
• W2113815624 title "Analysis of the cerebral cortex in holoprosencephaly with attention to the sylvian fissures." @default.
• W2113815624 cites W1532683920 @default.
• W2113815624 cites W1759401885 @default.
• W2113815624 cites W1911924729 @default.
• W2113815624 cites W1964311739 @default.
• W2113815624 cites W197001706 @default.
• W2113815624 cites W1988183526 @default.
• W2113815624 cites W1999340818 @default.
• W2113815624 cites W2000988068 @default.
• W2113815624 cites W2032408124 @default.
• W2113815624 cites W2068861805 @default.
• W2113815624 cites W2076401949 @default.
• W2113815624 cites W2081071953 @default.
• W2113815624 cites W2113214429 @default.
• W2113815624 cites W2119245177 @default.
• W2113815624 cites W2139681743 @default.
• W2113815624 cites W2160488751 @default.
• W2113815624 cites W2164853195 @default.
• W2113815624 cites W2412834413 @default.
• W2113815624 cites W3020958355 @default.
• W2113815624 cites W577064011 @default.
• W2113815624 cites W594349589 @default.
• W2113815624 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7975520" @default.
• W2113815624 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11827887" @default.
• W2113815624 hasPublicationYear "2002" @default.
• W2113815624 type Work @default.
• W2113815624 sameAs 2113815624 @default.
• W2113815624 citedByCount "15" @default.
• W2113815624 countsByYear W21138156242014 @default.
• W2113815624 countsByYear W21138156242018 @default.
• W2113815624 crossrefType "journal-article" @default.
• W2113815624 hasAuthorship W2113815624A5013333842 @default.
• W2113815624 hasAuthorship W2113815624A5018703759 @default.
• W2113815624 hasAuthorship W2113815624A5038583289 @default.
• W2113815624 hasAuthorship W2113815624A5076301593 @default.
• W2113815624 hasAuthorship W2113815624A5076632414 @default.
• W2113815624 hasConcept C105702510 @default.
• W2113815624 hasConcept C118552586 @default.
• W2113815624 hasConcept C126322002 @default.
• W2113815624 hasConcept C15744967 @default.
• W2113815624 hasConcept C169760540 @default.
• W2113815624 hasConcept C172680121 @default.
• W2113815624 hasConcept C2776395126 @default.
• W2113815624 hasConcept C2777348757 @default.
• W2113815624 hasConcept C2779234561 @default.
• W2113815624 hasConcept C2781041448 @default.
• W2113815624 hasConcept C2781374659 @default.
• W2113815624 hasConcept C54355233 @default.
• W2113815624 hasConcept C58693492 @default.
• W2113815624 hasConcept C71924100 @default.
• W2113815624 hasConcept C86803240 @default.
• W2113815624 hasConceptScore W2113815624C105702510 @default.
• W2113815624 hasConceptScore W2113815624C118552586 @default.
• W2113815624 hasConceptScore W2113815624C126322002 @default.
• W2113815624 hasConceptScore W2113815624C15744967 @default.
• W2113815624 hasConceptScore W2113815624C169760540 @default.
• W2113815624 hasConceptScore W2113815624C172680121 @default.
• W2113815624 hasConceptScore W2113815624C2776395126 @default.
• W2113815624 hasConceptScore W2113815624C2777348757 @default.
• W2113815624 hasConceptScore W2113815624C2779234561 @default.
• W2113815624 hasConceptScore W2113815624C2781041448 @default.
• W2113815624 hasConceptScore W2113815624C2781374659 @default.
• W2113815624 hasConceptScore W2113815624C54355233 @default.
• W2113815624 hasConceptScore W2113815624C58693492 @default.
• W2113815624 hasConceptScore W2113815624C71924100 @default.
• W2113815624 hasConceptScore W2113815624C86803240 @default.
• W2113815624 hasIssue "1" @default.
• W2113815624 hasLocation W21138156241 @default.
• W2113815624 hasOpenAccess W2113815624 @default.
• W2113815624 hasPrimaryLocation W21138156241 @default.
• W2113815624 hasRelatedWork W134395724 @default.
• W2113815624 hasRelatedWork W1532683920 @default.
• W2113815624 hasRelatedWork W1759401885 @default.
• W2113815624 hasRelatedWork W1911924729 @default.
• W2113815624 hasRelatedWork W1972001067 @default.
• W2113815624 hasRelatedWork W1998844725 @default.
• W2113815624 hasRelatedWork W1999340818 @default.
• W2113815624 hasRelatedWork W2010614235 @default.
• W2113815624 hasRelatedWork W2011231507 @default.
• W2113815624 hasRelatedWork W2035548394 @default.
• W2113815624 hasRelatedWork W2042080745 @default.
• W2113815624 hasRelatedWork W2043283250 @default.
• W2113815624 hasRelatedWork W2051391931 @default.
• W2113815624 hasRelatedWork W2060331223 @default.
• W2113815624 hasRelatedWork W2080030928 @default.
• W2113815624 hasRelatedWork W2081071953 @default.
• W2113815624 hasRelatedWork W2113214429 @default.
• W2113815624 hasRelatedWork W2119245177 @default.
• W2113815624 hasRelatedWork W2124324375 @default.

• next