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- W2113840968 abstract "Glioblastoma has a poor prognosis, with few therapeutic options if it recurs. We report a case in which we were able to inhibit the growth of a recurrent glioblastoma by weekly single-dose administration of interferon-beta.A patient with recurrent glioblastoma after radiation and chemotherapy was treated with nimustine and interferon-beta. After 2 cycles of nimustine, the patient's leukocyte, neutrophil, and platelet counts showed grade 4 toxicity according to the National Cancer Institute's Common Toxicity Criteria. The patient was treated with a weekly single dose of interferon-beta at 6 x 10(6) IU. The tumor showed no remarkable changes after 18 months, and the patient's Karnofsky performance status remained at 50%.The administration of interferon-beta produced long-term control in one case of glioblastoma and may be an effective therapy." @default.
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- W2113840968 date "2011-01-01" @default.
- W2113840968 modified "2023-09-25" @default.
- W2113840968 title "Effectiveness of Interferon-Beta Therapy for Recurrent Glioblastoma: A Case Report" @default.
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- W2113840968 doi "https://doi.org/10.1177/030089161109700121" @default.
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