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- W2113886817 abstract "THE response of the male frog (Rana pipiens) to gonadotropins is by now well known (1, 2, 3). This highly useful reaction forms the basis of the widely used male frog diagnostic test for pregnancy. It is less well known that these amphibia will also react with great constancy to adrenalin(4). Except for the report of Greenblatt (5) and a few diverse endocrinologic observations made as control studies in the course of pregnancy diagnostic work, very little is known about the male frog in regard to the pathways and mechanisms by which an injected substance is absorbed, disseminated and evokes the release of motile sperm. The relationship of the adrenalin reaction to the gonadotropic response is also unknown. The suggestion made by Greenblatt et al. that adrenalin and gonadotropin act through the pituitary cannot be confirmed by us (6). Several excellent anatomic studies are available which provide a relatively clear picture of the genito-urinary and endocrine systems of the male frog (7, 8). Even in this better established field of morphology, however, doubt still exists as to whether a functioning adrenal gland is present in the Rana pipiens (9). Nests of apparent adrenal cortical cells but no medullary cells are found dispersed along the ventral surface of the kidneys, but attempts at elucidating their function have proven inconclusive. The widespread use of male frogs is based, then, largely on a few scattered observations." @default.
- W2113886817 created "2016-06-24" @default.
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- W2113886817 date "1952-03-01" @default.
- W2113886817 modified "2023-09-25" @default.
- W2113886817 title "STUDIES ON THE MECHANISM OF THE SPERMATIC RELEASE OF THE MALE NORTH AMERICAN FROG (RANA PIPIENS): REACTION TO VARIOUS HORMONES*" @default.
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- W2113886817 doi "https://doi.org/10.1210/jcem-12-3-354" @default.
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