Matches in SemOpenAlex for { <https://semopenalex.org/work/W2113962330> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2113962330 endingPage "53" @default.
- W2113962330 startingPage "51" @default.
- W2113962330 abstract "Two recent crystal structures of membrane attack complex/perforin (MACPF) domains found in the complement and perforin families unexpectedly reveal that some proteins of the immune system share a common core fold with their bacterial targets. Although a relationship between MACPF proteins and the previously characterized bacterial cholesterol-dependent cytolysins (CDCs) is not detectable by sequence analysis, the MACPF structures show that eukaryotic defense and bacterial CDC attack share a common mechanism of membrane insertion and pore formation. Two recent crystal structures of membrane attack complex/perforin (MACPF) domains found in the complement and perforin families unexpectedly reveal that some proteins of the immune system share a common core fold with their bacterial targets. Although a relationship between MACPF proteins and the previously characterized bacterial cholesterol-dependent cytolysins (CDCs) is not detectable by sequence analysis, the MACPF structures show that eukaryotic defense and bacterial CDC attack share a common mechanism of membrane insertion and pore formation." @default.
- W2113962330 created "2016-06-24" @default.
- W2113962330 creator A5013271893 @default.
- W2113962330 creator A5021508521 @default.
- W2113962330 date "2008-02-01" @default.
- W2113962330 modified "2023-09-24" @default.
- W2113962330 title "Friend or foe: the same fold for attack and defense" @default.
- W2113962330 cites W1818853492 @default.
- W2113962330 cites W1968109964 @default.
- W2113962330 cites W1970026235 @default.
- W2113962330 cites W1972222351 @default.
- W2113962330 cites W1980273151 @default.
- W2113962330 cites W1984421966 @default.
- W2113962330 cites W1990554391 @default.
- W2113962330 cites W2001276190 @default.
- W2113962330 cites W2009619778 @default.
- W2113962330 cites W2012479760 @default.
- W2113962330 cites W2018054206 @default.
- W2113962330 cites W2018628082 @default.
- W2113962330 cites W2072663421 @default.
- W2113962330 cites W2081335753 @default.
- W2113962330 cites W2089934202 @default.
- W2113962330 cites W2090821297 @default.
- W2113962330 cites W2094197540 @default.
- W2113962330 cites W2139089713 @default.
- W2113962330 cites W2140396902 @default.
- W2113962330 cites W315197452 @default.
- W2113962330 doi "https://doi.org/10.1016/j.it.2007.11.003" @default.
- W2113962330 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18248850" @default.
- W2113962330 hasPublicationYear "2008" @default.
- W2113962330 type Work @default.
- W2113962330 sameAs 2113962330 @default.
- W2113962330 citedByCount "19" @default.
- W2113962330 countsByYear W21139623302012 @default.
- W2113962330 countsByYear W21139623302013 @default.
- W2113962330 countsByYear W21139623302014 @default.
- W2113962330 countsByYear W21139623302016 @default.
- W2113962330 countsByYear W21139623302017 @default.
- W2113962330 countsByYear W21139623302020 @default.
- W2113962330 crossrefType "journal-article" @default.
- W2113962330 hasAuthorship W2113962330A5013271893 @default.
- W2113962330 hasAuthorship W2113962330A5021508521 @default.
- W2113962330 hasConcept C111684460 @default.
- W2113962330 hasConcept C167672396 @default.
- W2113962330 hasConcept C203014093 @default.
- W2113962330 hasConcept C2776062744 @default.
- W2113962330 hasConcept C79196540 @default.
- W2113962330 hasConcept C86803240 @default.
- W2113962330 hasConcept C8891405 @default.
- W2113962330 hasConcept C95444343 @default.
- W2113962330 hasConceptScore W2113962330C111684460 @default.
- W2113962330 hasConceptScore W2113962330C167672396 @default.
- W2113962330 hasConceptScore W2113962330C203014093 @default.
- W2113962330 hasConceptScore W2113962330C2776062744 @default.
- W2113962330 hasConceptScore W2113962330C79196540 @default.
- W2113962330 hasConceptScore W2113962330C86803240 @default.
- W2113962330 hasConceptScore W2113962330C8891405 @default.
- W2113962330 hasConceptScore W2113962330C95444343 @default.
- W2113962330 hasIssue "2" @default.
- W2113962330 hasLocation W21139623301 @default.
- W2113962330 hasLocation W21139623302 @default.
- W2113962330 hasOpenAccess W2113962330 @default.
- W2113962330 hasPrimaryLocation W21139623301 @default.
- W2113962330 hasRelatedWork W1980273151 @default.
- W2113962330 hasRelatedWork W2006089651 @default.
- W2113962330 hasRelatedWork W2008171369 @default.
- W2113962330 hasRelatedWork W2026099298 @default.
- W2113962330 hasRelatedWork W2048696783 @default.
- W2113962330 hasRelatedWork W2052703083 @default.
- W2113962330 hasRelatedWork W2113962330 @default.
- W2113962330 hasRelatedWork W2117667068 @default.
- W2113962330 hasRelatedWork W2387591265 @default.
- W2113962330 hasRelatedWork W2971131494 @default.
- W2113962330 hasVolume "29" @default.
- W2113962330 isParatext "false" @default.
- W2113962330 isRetracted "false" @default.
- W2113962330 magId "2113962330" @default.
- W2113962330 workType "article" @default.